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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
ASCT2
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "ASCT2" in MCE Product Catalog:
34
34 Publications Verification
V-9302 is a competitive antagonist of transmembrane glutamine flux. V-9302 selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) not ASCT1. V-9302 inhibits ASCT2-mediated glutamine uptake (IC50=9.6 μM) in HEK-293 cells .
34
34 Publications Verification
V-9302 hydrochloride is a competitive antagonist of transmembrane glutamine flux. V-9302 hydrochloride selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) not ASCT1. V-9302 hydrochloride inhibits ASCT2-mediated glutamine uptake (IC50=9.6 µM) in HEK-293 cells .
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7 Cited Publications
Cat. No.: HY-W011391
CAS No.: 67953-08-6
GPNA hydrochloride is a well known substrate of the enzyme γ-glutamyltransferase (GGT). GPNA hydrochloride is a specific glutamine (Gln) transporter ASCT2 inhibitor. GPNA hydrochloride also inhibit Na +-dependent carriers, such as SNAT family (SNAT1/2/4/5), and the Na +-independent leucine transporters LAT1/2. GPNA reversibly induces apoptosis in A549 cells .
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4 Cited Publications
Cat. No.: HY-N0327
CAS No.: 129277-38-9
Category:
Natural Products Campanulaceae Metabolic Disease Codonopsis pilosula (Franch.) Nannf. Plants Disease Research Fields
Target:
Cat. No.: HY-P99654
CAS No.: 2245205-37-0
Synonyms: INT-001
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Research Areas:
Cat. No.: HY-165740
CAS No.: 65988-71-8
Synonyms: Disialoganglioside GD2
Ganglioside GD2 (Disialoganglioside GD2) is a tumor-associated antigen. Ganglioside GD2 shows limited expression in normal tissues but is overexpressed in multiple tumor types, and thus can serve as a target in cancer. Ganglioside GD2 is associated with tumor development and malignant phenotypes, and its mechanism of action relies on enhancing cell proliferation, motility, migration, adhesion and invasion, with specific effects depending on the tumor type [2].
Cat. No.: HY-163199
CAS No.: 3032651-29-6
ASCT2-IN-2 (compound 25e) is an ASCT2 inhibitor with IC50 of 5.14 μM. ASCT2-IN-2 regulates amino acid metabolism as well as mTOR signaling and thereby induces cell apoptosis. ASCT2-IN-2 inhibits tumor growth .
Cat. No.: HY-144354S
CAS No.: 51494-04-3
Cat. No.: HY-34611
CAS No.: 25691-37-6
Synonyms: N-Boc-L-2,4-diaminobutyric acid; Boc-Dab-OH
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Cat. No.: HY-RS13056
Target:
Research Areas:
SLC1A5 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC1A5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
SN40 is a potent amino acid transport (AAT) inhibitor with Kis of 7.29 μM, 2.42 μM, 2.94 μM, 5.55 μM, 24.43 μM and 5.55 μM for rat ASCT2, human ASCT2, EAAT1, EAAT2, EAAC1 and EAAT5, respectively. SN40 can be used for researching anticancer .
SN40 hydrochloride is a potent amino acid transport (AAT) inhibitor with Kis of 7.29 μM, 2.42 μM, 2.94 μM, 5.55 μM, 24.43 μM and 5.55 μM for rat ASCT2, human ASCT2, EAAT1, EAAT2, EAAC1 and EAAT5, respectively. SN40 hydrochloride can be used for researching anticancer .
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Cat. No.: HY-P703196
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ASCT2; M7V1; RDR; RDRC
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Source:
Cat. No.: HY-14889
CAS No.: 222727-43-7
Research Areas:
Fluciclovine is an amino acid analogue that can enter cells by targeting the amino acid transporters on the cell surface (mainly ASCT2 and LAT1). After being labeled with ¹⁸F, ¹⁸F-fluciclovine can be used as an imaging agent for positron emission tomography (PET) for prostate diagnosis imaging .
Cat. No.: HY-RS23273
Target:
Research Areas:
Slc1a5 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc1a5 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16831
Target:
Research Areas:
Slc1a5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc1a5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P704158
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Neutral amino acid transporter B(0); SLC1A5; ATB(0); Baboon M7 virus receptor; RD114/simian type D retrovirus receptor; Sodium-dependent neutral amino acid transporter type 2; Solute carrier family 1 member5; ASCT2; M7V1; RDR; RDRC; AAAT; ASCT2M7VS1; M7V1ATBO; R16; RD114; RDRCFLJ31068
Cat. No.: HY-P81435
Synonyms: SLC1A5 ; ASCT2; M7V1, RDR, RDRC; Neutral amino acid transporter B(0); ATB(0); Baboon M7 virus receptor; RD114/simian type D retrovirus receptor; Sodium-dependent neutral amino acid transporter type 2; Solute carrier family 1 member 5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
