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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
63 Results for "
Biotransformation
" in MedChemExpress (MCE) Product Catalog:
Products (63)
63 Results for "Biotransformation" in MCE Product Catalog:
2
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Cholesterol oxidase, Microorganism (ChOx, Microorganism) (EC 1.1.3.6) is a cholesterol oxidase identified from bacterial sources. Cholesterol oxidase, Microorganism catalyzes the oxidation of cholesterol to 4-cholesten-3-one, while simultaneously reducing oxygen to hydrogen peroxide. Cholesterol oxidase, Microorganism retains its enzymatic activity and exhibits improved catalytic efficiency upon immobilization. Cholesterol oxidase, Microorganism is applicable for cholesterol detection, steroid biotransformation, and research on tuberculosis-related diseases .
Cat. No.: HY-W015590
CAS No.: 614-75-5
Category:
Monophenols Ketones, Aldehydes, Acids Disease markers Endocrine diseases Phenols Nervous System Disorder Endogenous metabolite
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Cat. No.: HY-P2816
CAS No.: 37278-89-0
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Xylanase is an enzyme targeting 1,4-β-D-xylan that randomly cleaves the β-1,4 backbone of xylan, a complex polysaccharide in plant cell walls. Xylanase finds applications in the food, feed and industrial sectors, including pulp and paper processing, baking, animal feed improvement, and biotransformation of waste .
Cat. No.: HY-173351
CAS No.: 2901806-51-5
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G-6599 is a covalent molecular glue degrader targeting SMARCA2/SMARCA4, with DC50 values of 0.017 nM and 0.057 nM against SMARCA2 and SMARCA4 in SW1573 cells, respectively. G-6599 exhibits proteome selectivity for SMARCA2, SMARCA4, and PBRM1. G-6599 induces the assembly of the SMARCA2-FBXO22 ternary complex, enabling ubiquitination and proteasomal degradation of both proteins via the ubiquitin-proteasome pathway without the need for biotransformation. G-6599 shows antiproliferative effects in relevant cancer cell models. G-6599 can be used for research on androgen-dependent prostate cancer and SMARCA4-mutant non-small cell lung cancer .
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Diaphorase, Recombinant microorganisms can be obtained from anaerobic sludge organisms. Diaphorase catalyzes biotransformation of hexahydro-1,3, 5-trinitro-1,3, 5-triazine (RDX) by denitrification .
Synonyms: BIA 3-202
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Nebicapone (BIA 3-202), a reversible catechol-O-methyltransferase (COMT) inhibitor, is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to 3-O-methyl-DOPA by inhibition of COMT, and it is potential for the treatment of Parkinson's disease .
Cat. No.: HY-W013058
CAS No.: 84852-53-9
Synonyms: DBDPE; 1,2-Bis(perbromophenyl)ethane
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Decabromodiphenyl ethane (DBDPE) is a brominated flame retardant. Decabromodiphenyl ethane induces ROS-related cytotoxicity and apoptosis in human hepatoma cells, causes hepatocyte damage through oxidative stress, endoplasmic reticulum stress and decreased CYP3A expression, and accumulates and undergoes biotransformation in animal tissues. Decabromodiphenyl ethane can be used to study the environmental toxicology and biological effects of brominated flame retardants .
Cat. No.: HY-W004301
CAS No.: 112-54-9
Cat. No.: HY-N7921
CAS No.: 1006683-97-1
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β-N-Acetylhexosaminidase, Porcine kidney is a glycosidase with transglycosylation activity, used to generate health-beneficial human milk oligosaccharides, and it effectively interacts with low molecular weight sugar alcohols (such as glycerol, erythritol, and xylitol). The enzyme exhibits optimal activity at pH 5 and 40 °C, and shows high thermal stability (up to 55°C) when bound to the cell wall. β-N-Acetylhexosaminidase holds promise for applications in the biotransformation of Chitin (HY-126389) and research in the food health sector .
Cat. No.: HY-W102516
CAS No.: 1162-56-7
Synonyms: Δ6-Progesterone
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Cat. No.: HY-W153159
CAS No.: 13062-76-5
Category:
Alkaloids Monophenols Other Alkaloids Phenols Plants Gramineae Extract Hordeum distichon L.
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Cat. No.: HY-N16639
CAS No.: 105330-51-6
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Cat. No.: HY-N11677
CAS No.: 1035154-52-9
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Cholesterol oxidase, rhodococcus sp (ChOx, rhodococcus sp) (EC 1.1.3.6) is a cholesterol oxidase identified from bacterial sources. Cholesterol oxidase, rhodococcus sp catalyzes the oxidation of cholesterol to 4-cholesten-3-one, while simultaneously reducing oxygen to hydrogen peroxide. Cholesterol oxidase, rhodococcus sp retains its enzymatic activity and exhibits improved catalytic efficiency upon immobilization. Cholesterol oxidase, rhodococcus sp is applicable for cholesterol detection, steroid biotransformation, and research on tuberculosis-related diseases .
Cat. No.: HY-154916
CAS No.: 139958-51-3
Synonyms: 13-DMT; 13-O-Demethyl FK 506
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13-O-Desmethyl tacrolimus (13-DMT; 13-O-Demethyl FK 506) is the major metabolite of Tacrolimus (HY-13756) formed via cytochrome P450 3A-mediated biotransformation. The ratio of 13-O-Desmethyl tacrolimus to Tacrolimus serves as a biomarker for myelotoxicity and hepatotoxicity .
Cat. No.: HY-W153897
CAS No.: 370-98-9
Category:
Alkaloids Human Gut Microbiota Metabolites Other Alkaloids Acacia auriculiformis A.Cunn. ex Benth Leguminosae Extract Plants Endogenous metabolite
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Cat. No.: HY-N8911
CAS No.: 121927-96-6
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Cat. No.: HY-123340
CAS No.: 56784-39-5
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Ozolinone is a diuretic metabolite formed by biotransformation of the diuretic elkapin in mammals and exerts a potent diuretic effect in a variety of species .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
