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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
75 Results for "
Caspase Substrate
" in MedChemExpress (MCE) Product Catalog:
Products (75)
75 Results for "Caspase Substrate" in MCE Product Catalog:
25
24
5
5 Cited Publications
Cat. No.: HY-P1003
CAS No.: 169332-61-0
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4
4 Cited Publications
Cat. No.: HY-P2377
CAS No.: 219137-85-6
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3
3 Cited Publications
Cat. No.: HY-P1093
CAS No.: 210345-03-2
2
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2
2 Cited Publications
Cat. No.: HY-P2615A
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1
1 Cited Publications
Cat. No.: HY-N4183
CAS No.: 72357-31-4
Category:
Flavonoids Leguminosae Flavones Phenols Polyphenols Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer
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1
1 Cited Publications
Cat. No.: HY-172158
CAS No.: 140481-05-6
Research Areas:
ALKBH5-IN-5 is a highly selective ALKBH5 (IC50 = 0.62 μM, Kd = 804 nM). ALKBH5-IN-5 disrupts ALKBH5 binding to m 6A-RNA and 6mA-DNA substrates. ALKBH5-IN-5 promotes differentiation, induces apoptosis, cause G2-M phase arrest and exerts strong antiproliferative effects in cancer cells. ALKBH5-IN-5 reduces TACC3 and MYC protein levels and increases cleaved caspase-3 levels. ALKBH5-IN-5 exerts antitumor activity in tumor xenograft mice models. ALKBH5-IN-5 can be used for the research of acute myeloid leukemia .
1
1 Cited Publications
Cat. No.: HY-P1169
CAS No.: 211990-57-7
1
1 Cited Publications
Cat. No.: HY-P5983
CAS No.: 210345-01-0
Cat. No.: HY-P1986
CAS No.: 1135416-11-3
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Cardiovascular Disease Neurological Disease Inflammation/Immunology
SYM 2081 is a kainate receptor agonist. SYM 2081 is a substrate of EAAT1 (Km of 54 μM). SYM 2081 inhibits EAAT2-mediated glutamate transport (Kb is 3.4 μM in Xenopus oocytes), modulates Apoptotic signaling pathways (increases Bcl-2 and decreases Bax/caspase-3 expression). SYM 2081 exhibits neuroprotective activity. SYM 2081 can be used in the study of hypoxic-ischemic brain damage and inflammatory or neuropathic pain .
Cat. No.: HY-P4547
CAS No.: 189275-74-9
Synonyms: AC-WEHD-AMC
Cat. No.: HY-D1652
CAS No.: 292633-16-0
Ac-LEHD-AMC is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm). Caspase-9 can induce hydrolysis of Ac-LEHD-AMC, resulting in the release of AMC fluorophore and its fluorescence can be used to quantify caspase-9 activity .
Cat. No.: HY-P2065
CAS No.: 219137-97-0
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Cat. No.: HY-P10244F
Cat. No.: HY-P2091
CAS No.: 149231-66-3
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Cat. No.: HY-P2617A
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Cat. No.: HY-P5348
CAS No.: 921771-40-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
