1 Result for "

Cl - currents

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Cl - currents" in MCE Product Catalog:

Cat. No.: HY-100686
CAS No.: 152273-12-6
Purity:  99.85%
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

U93631 is a GABAA receptor inhibitor targeting the picrotoxin (HY-101391) site, which exhibits higher inhibitory potency in receptors lacking α subunits. U93631 blocks GABA-induced chloride currents, exerts a mild initial stimulatory effect on activated currents, but its activity decreases in β2T246F mutant receptors. U93631 can serve as a ligand for the convulsant site of GABAA receptors in relevant studies .
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