2 Results for "

IMR90 fibroblasts

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "IMR90 fibroblasts" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-12303
CAS No.: 300586-90-7
Purity:  99.56%
Target:  

Oct3/4 TET Protein

Research Areas:  

Cancer

OAC1 is a potent Oct4 activator. OAC1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. OAC1 activates OCT4 through upregulation of HOXB4 expression. OAC1 increases transcription of the Oct4-Nanog-Sox2 triad and TET1. OAC1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time .
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Cat. No.: HY-175806
CAS No.: 1372792-51-2
Research Areas:  

Cancer

CS47 is a Thioredoxin Reductase 1 (TRXR1) inhibitor and ferroptosis inducer. CS47 binds non-covalently to sites between the FAD and NADPH pockets of TRXR1. CS47 drives glutathione depletion, lipid reactive oxygen species accumulation, HMOX1-dependent iron overload, and selective cytotoxicity in lung cancer cells. CS47 can be used for the research of lung cancer .
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