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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
46 Results for "
J2
" in MedChemExpress (MCE) Product Catalog:
Products (46)
46 Results for "J2" in MCE Product Catalog:
6
HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof. HSP27 inhibitor J2 (J2) remarkably enhances the antiproliferative activity of 17-AAG and sensitizes cisplatin-induced lung cancer cell growth inhibition [2].
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6 Publications Verification
Cat. No.: HY-N0319
CAS No.: 115841-09-3
Category:
Labiatae Ketones, Aldehydes, Acids Samanea saman (Jacq.) Merr. Phenols Polyphenols Plants Disease Research Fields Cancer
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4
4 Cited Publications
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GSK-J2 is an isomer of GSK-J1 that does not have any specific activity. GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A.
3
3 Cited Publications
Synonyms: 15d-PGJ2; 15-Deoxy-Δ12,14-PGJ2
Category:
Neurological Disease Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology
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2
2 Cited Publications
Cat. No.: HY-N0515
CAS No.: 945619-74-9
1
1 Cited Publications
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LKY-047, a Decursin derivative, is a potent and selective reversible competitive cytochrome P45022J2 (CYP2J2) inhibitor with an IC50 of 1.7 μM. LKY-047 is inactive against other human P450s, such as CYPs 1A2, 2A6, 2B6, 2C8, 2C9, 2C19, 2D6, 2E1, and 3A .
1
1 Cited Publications
Synonyms: 15d-PGJ2-d4; 15-Deoxy-Δ12,14-PGJ2-d4
1
1
Synonyms: PGJ2
Cat. No.: HY-175443
CAS No.: 2034182-75-5
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AMPA-IN-3 is an AMPA receptor inhibitor. AMPA-IN-3 inhibits TARP J2-dependent AMPA receptor activity with a pIC50 value of 10.7. A AMPA-IN-3 can be used for the research of neurological disease .
Cat. No.: HY-N6744
CAS No.: 50335-03-0
Synonyms: Δ12-PGJ2
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Cat. No.: HY-125737
Synonyms: 15-Deoxy-Δ12,14-PGJ2 Glutathione
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15-deoxy-Δ12,14-Prostaglandin J2 glutathione (15-deoxy-Δ12,14-PGJ2 glutathione) is a non-enzymatic adduct formed from 15-deoxy-Δ12,14-PGJ2 and glutathione. The biological properties of this compound have not been characterized.
Cat. No.: HY-N0515R
CAS No.: 945619-74-9
Cat. No.: HY-176243
CAS No.: 1947405-90-4
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15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester is a derivate of 15-Deoxy-Δ-12,14-prostaglandin J2 (HY-108568). 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. 15-Deoxy-Δ-12,14-prostaglandin J2 is a selective PPARγ (EC50 of 2 µM) and a covalent PPARδ agonist. 15-Deoxy-Δ-12,14-prostaglandin J2 promotes efficient differentiation of C3H10T1/2 fibroblasts to adipocytes with an EC50 of 7 μM [2] .
Cat. No.: HY-113366S
CAS No.: 2738376-80-0
Cat. No.: HY-15648H
CAS No.: 1797983-32-4
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GSK-J5 hydrochloride is a cell-permeable?ester derivative of?GSK J2 (HY-15648A), inactive. GSK-J5 hydrochloride is also an?isomer of GSK-J4 (HY-15648B) and often used as a negative group .
Cat. No.: HY-15648I
CAS No.: 2108665-15-0
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GSK-J2 sodium is the sodium form of GSK-J2 (HY-15648A). GSK-J2 is an isomer of GSK-J1, and does not have any specific activity. GSK-J1 (HY-15648) is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A .
Cat. No.: HY-123897
CAS No.: 89595-70-0
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
