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PDT

" in MedChemExpress (MCE) Product Catalog:

58

Inhibitors & Agonists

5

Fluorescent Dye

1

Biochemical Assay Reagents

2

Peptides

5

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Products

1

Isotope-Labeled Compounds

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0988
    R-Phycoerythrin

    R-PE

    		 Fluorescent Dye Apoptosis Cancer
    R-Phycoerythrin is found in Heterosiphonia japonica. R-Phycoerythrin is an orange-red fluorescent probe with α, β, and γ subunits. R-Phycoerythrin can be used in photodynamic therapy (PDT) to induce apoptosis in tumor cells. R-Phycoerythrin can be used in fluorescence microscopy, flow cytometry, and immunofluorescence analysis (Ex: 495 nm).
    R-Phycoerythrin
  • HY-128973
    Pyropheophorbide-a
    3 Publications Verification

    		 Reactive Oxygen Species (ROS) Cancer
    Pyropheophorbide-a (Ppa) is a photosensitizer used in photodynamic therapy (PDT) for tumors. Pyropheophorbide-a exhibits phototoxic effects on tumor cells, such as cervical cancer cells, and also has anti-lipogenesis activity. Pyropheophorbide-a shows potential for research in the fields of cancer and age-related macular degeneration (AMD). Pyropheophorbide-a derivatives also demonstrate inhibitory activity against tumor cells .
    Pyropheophorbide-a
  • HY-19204
    Zinc phthalocyanine

    ZnPc

    		 Ligands for Target Protein for PROTAC Reactive Oxygen Species (ROS) Apoptosis Caspase Cancer
    Zinc phthalocyanine (ZnPc) is commonly applied in industry (catalysts, photoconductors) and biomedical (photodynamic therapy, PDT). Zinc phthalocyanine can be used to photooxidise cyclohexane and is promising for research of solar-cell applications .
    Zinc phthalocyanine
  • HY-16488
    Temoporfin
    10+ Cited Publications

    m-THPC; KW2345

    		 Reactive Oxygen Species (ROS) Cancer
    Temoporfin (m-THPC), a reduced porphyrin, is a potent second-generation photosensitizer. Temoporfin can be used in the research of photodynamic therapy (PDT) for head and neck cancers .
    Temoporfin
  • HY-P2213
    GPLGIAGQ

    		MMP Apoptosis Cancer
    GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT) .
    GPLGIAGQ
  • HY-N2575
    Hypocrellin A
    2 Publications Verification

    		 PKC Bacterial Parasite HIV VSV VEGFR Bcl-2 Family Apoptosis Infection Metabolic Disease Cancer
    Hypocrellin A is a PKC inhibitor that exerts antidiabetic activity by reversing the effects of high glucose on endothelin (ET-1) expression. Hypocrellin A is also a photosensitizer for photodynamic therapy (PDT) with anticancer, antibacterial and antiviral activities, especially against human immunodeficiency virus (HIV). In addition, Hypocrellin-A also possesses anti-Leishmania activity (IC50=0.27 μg/ml) .
    Hypocrellin A
  • HY-16045
    Hexaminolevulinate hydrochloride

    Hexyl 5-aminolevulinate hydrochloride; P-1206; 5-Aminolevulinic acid hexyl ester hydrochloride

    		 Fluorescent Dye Cancer
    Hexaminolevulinate (Hexyl 5-aminolevulinate) hydrochloride, a porphyrin precursor, is a photosensitiser that can be used in photodynamic therapy (PDT) for certain tumor. Hexaminolevulinate hydrochloride can improve the visualisation of bladder tumours .
    Hexaminolevulinate hydrochloride
  • HY-137473
    Methyl pyropheophorbide-a
    2 Publications Verification

    Pyropheophorbide-a methyl ester

    		 Apoptosis Cancer
    Methyl pyropheophorbide-a (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Methyl pyropheophorbide-a has photodynamic activity and can induce apoptosis and inhibit tumor growth .
    Methyl pyropheophorbide-a
  • HY-13722
    HPPH
    3 Publications Verification

    Photochlor

    		 Reactive Oxygen Species (ROS) Cancer
    HPPH (Photochlor) is a second generation photosensitizer, which acts as a photodynamic therapy (PDT) agent.
    HPPH
  • HY-16477
    Talaporfin sodium
    4 Publications Verification

    ME2906; Mono-L-aspartyl chlorin e6; NPe6

    		 Photosensitizer Cancer
    Talaporfin (ME2906) sodium is a chlorin based photosensitizer. Talaporfin sodium can be used for the research of various cancers by using photodynamic therapy (PDT) .
    Talaporfin sodium
  • HY-A0169A
    Methyl aminolevulinate hydrochloride
    1 Publications Verification

    		 Reactive Oxygen Species (ROS) Photosensitizer Cancer
    Methyl aminolevulinate hydrochloride is a sensitizer used in photodynamic therapy (PDT). Methyl aminolevulinate hydrochloride penetrates the skin and induces the production of photoactive porphyrins including protoporphyrin IX in cells; upon exposure to appropriate light, it generates ROS, which triggers cellular oxidation and cell death. Methyl aminolevulinate hydrochloride acts as a photo-damage reversing agent through epidermal reconstruction, cytokine-mediated activation of dermal fibroblasts, elastin breakdown, new collagen formation, and compression of dilated capillaries. Methyl aminolevulinate hydrochloride reduces the expression of the proliferation marker Ki-67 and the early skin carcinogenesis marker TP53. Methyl aminolevulinate hydrochloride delays the onset of ultraviolet-induced skin tumors and reduces tumor burden in hairless mice. Methyl aminolevulinate hydrochloride is applicable to research related to actinic keratosis and basal cell carcinoma .
    Methyl aminolevulinate hydrochloride
  • HY-N6743
    Cercosporin

    CGP049090

    		 PKC Cancer
    Cercosporin is produced by a plant pathogen, Pseudocercosporella capsellae. Cercosporin is a potent photosensitizer with a short activation wavelength, mostly suitable for superficial photodynamic therapy (PDT) treatments, especially when it is necessary to avoid perforations . Cercosporin contains the perylenequinone structural features necessary to PKC activity with an IC50 of 0.6-1.3 μM .
    Cercosporin
  • HY-U00128
    PPA-904

    		Parasite Infection Inflammation/Immunology
    PPA-904 is a specific phenothiazine photosensitizer in photodynamic research (PDT) research, especially topical application for cutaneous leishmaniasis in vivo .
    PPA-904
  • HY-W130236
    Methylene Violet 3RAX

    		Cholinesterase (ChE) Cancer
    Methylene Violet 3RAX is a phenazine dye to stain the mitochondria of cells. Methylene Violet 3RAX can change the molecular structure of DNA, undermine the module of DNA, and induce the generation of the reactive singlet oxygen. Methylene Violet 3RAX shows inhibition for human erythrocyte AChE and human plasma BChE with an Kis of 1.58, 0.51 μM, respectively. Methylene Violet 3RAX has the potential for the research of potential photosensitizers for mitochondrial targeting action in PDT (photodynamic therapy) .
    Methylene Violet 3RAX
  • HY-137475
    Chlorin e6 trimethyl ester
    1 Publications Verification

    		 Reactive Oxygen Species (ROS) Cancer
    Chlorin e6 trimethyl ester, a methyl pheophorbide-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT) .
    Chlorin e6 trimethyl ester
  • HY-W854659
    Chlorin e6 trisodium
    15+ Cited Publications

    Ce6 trisodium

    		 Photosensitizer Cancer
    Chlorin e6 Ce6 (trisodium) is a water-soluble derivative of chlorophyll, belonging to the chlorin class of photosensitizers with an absorption wavelength range of 600-670 nm. Chlorin e6 trisodium emits characteristic red fluorescence upon light excitation, enabling real-time identification of tumor boundaries and progression. Chlorin e6 trisodium can be used for the study of photodynamic therapy (PDT) of cancers (bladder cancer) and fluorescence diagnosis of neoplastic lesions .
    Chlorin e6 trisodium
  • HY-151486
    GLUT1-IN-1

    		GLUT Cancer
    GLUT1-IN-1 is a glucose transporter 1 (GLUT1) inhibitor and has a GLUT1-specific inactivation ability. GLUT1-IN-1 exhibits concentration-dependent cytotoxicity for HeLa, A549 and HepG2 cells with IC50 values of 5.49 μM, 11.14 μM, and 8.73 μM, respectively. GLUT1-IN-1 can be used for the research of photodynamic therapy (PDT) and severals cancer .
    GLUT1-IN-1
  • HY-137474
    Purpurin 18 methyl ester

    		Photosensitizer Cancer
    Purpurin 18 methyl ester, a chlorophyll-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT). Purpurin 18 methyl ester has photodynamic activity to induce cancer cell death .
    Purpurin 18 methyl ester
  • HY-P2213A
    GPLGIAGQ TFA

    		MMP Apoptosis Cancer
    GPLGIAGQ TFA, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ TFA can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT) .
    GPLGIAGQ TFA
  • HY-N10611
    Elsinochrome A

    		Reactive Oxygen Species (ROS) Apoptosis Autophagy Fungal Fluorescent Dye Infection Cancer
    Elsinochrome A is a perylene quinone photosensitizer, and can generate reactive oxygen species (ROS) to induce apoptosis and autophagy under light excitation. Elsinochrome A also shows antifungal activity against C. albicans biofilm through photodynamic antimicrobial chemotherapy (PACT). Elsinochrome A can be used for research of photodynamic therapy (PDT) (Ex: 460 nm) .
    Elsinochrome A
  • HY-137473R
    Methyl pyropheophorbide-a (Standard)

    Pyropheophorbide-a methyl ester (Standard)

    		 Apoptosis Reference Standards Cancer
    Methyl pyropheophorbide-a (Standard) is the analytical standard of Methyl pyropheophorbide-a. This product is intended for research and analytical applications. Methyl pyropheophorbide-a (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Methyl pyropheophorbide-a has photodynamic activity and can induce apoptosis and inhibit tumor growth .
    Methyl pyropheophorbide-a (Standard)
  • HY-16488R
    Temoporfin (Standard)

    m-THPC (Standard); KW2345 (Standard)

    		 Reactive Oxygen Species (ROS) Reference Standards Cancer
    Temoporfin (Standard) is the analytical standard of Temoporfin. This product is intended for research and analytical applications. Temoporfin (m-THPC), a reduced porphyrin, is a potent second-generation photosensitizer. Temoporfin can be used in the research of photodynamic therapy (PDT) for head and neck cancers .
    Temoporfin (Standard)
  • HY-116525
    Octaethylporphyrin

    		Reactive Oxygen Species (ROS) Cancer
    Octaethylporphyrin is a porphyrin derivative. Octaethylporphyrin is a photodynamic therapy (PDT) agent .
    Octaethylporphyrin
  • HY-157470
    PPO-IN-6

    		Protoporphyrinogen IX oxidase Cancer
    PPO-IN-6 is a protoporphyrinogen oxidase (PPO) inhibitor that blocks the production of heme and chlorophyll. Pop-in-6 can be used IN the detection and research of cancer and other diseases .
    PPO-IN-6
  • HY-W035145
    Tris2,2′-bipyridineruthenium(II) hexafluorophosphate

    		Drug Intermediate Others
    Tris(2,2′-bipyridine)ruthenium(II)hexafluorophosphate can be used to prepare Ru(II)-containing photodynamic therapy (PDT) photosensitizers .
    Tris2,2′-bipyridineruthenium(II) hexafluorophosphate
  • HY-179415
    DHFR-IN-24

    		Dihydrofolate reductase (DHFR) Bacterial Infection
    DHFR-IN-24, a benzothiazole derivative, is a dihydrofolate reductase (DHFR) inhibitor. DHFR-IN-24 has intrinsic antibacterial activity against both Gram-positive and Gram-negative strains. DHFR-IN-24 synergistically combines DHFR inhibition with photodynamic therapy (PDT) for enhanced antibacterial activity against multidrug-resistant pathogens .
    DHFR-IN-24
  • HY-147690
    Photosensitizer-2

    		Photosensitizer Cancer
    Photosensitizer-2 (compound 1) is a organic D-π-A sensitizer against phototoxicity. Photosensitizer-2 contains an acrylic acid moiety that exerts high levels of phototoxicity. Photosensitizer-2 shows antitumor activity against HeLa cells, with IC50 values of 20.9 ± 4.5 μM (dark) and 0.046 ± 0.012 μM (irradiation), respectively .
    Photosensitizer-2
  • HY-157943
    Hexyl 5-aminolevulinate

    HAL

    		 Fluorescent Dye Cancer
    Hexyl 5-aminolevulinate (HAL) is a photosensitizer, and can increase the efficiency of PDT due to the high lipophilicity. Hexyl 5-aminolevulinate can be used for research of photodynamic therapy (PDT) .
    Hexyl 5-aminolevulinate
  • HY-162824
    Antitumor photosensitizer-6

    		Apoptosis Cancer
    Antitumor photosensitizer-6 (Compound Ru2) shows synergetic type I/II photosensitization and photocatalytic activity upon 595 nm light excitation. Ru2 induces intracellular redox imbalance and affects the biosynthetic and metabolic processes, leading to cell apoptosis. Antitumor photosensitizer-6 can be used for research of photodynamic therapy (PDT) .
    Antitumor photosensitizer-6
  • HY-155003
    TPEQM-DMA

    		Fluorescent Dye Cancer
    TPEQM-DMA is a NIR-II photosensitizer. TPEQM-DMA accumulates in cancerous mitochondria, and inhibits cancer cell growth. TPEQM-DMA has potent type-I phototherapeutic efficacy to overcome the intrinsic pitfalls of PDT in combating hypoxic tumors .
    TPEQM-DMA
  • HY-176724
    ZnPc-O3-JQ1

    		Epigenetic Reader Domain Reactive Oxygen Species (ROS) HIF/HIF Prolyl-Hydroxylase Cancer
    ZnPc-O3-JQ1 is a light-triggered BRD4 degrader. Under illumination, ZnPc-O3-JQ1 generates reactive oxygen species (ROS) that degrades BRD4. The degradation of BRD4 results in downregulation of HIF-1α, thereby counteracting the photodynamic therapy (PDT) resistance induced by tumor hypoxia. ZnPc-O3-JQ1 exhibits both Type I and Type II PDT mechanisms. The structure of ZnPc-O3-JQ1 consists of three parts: BRD4 ligand (HY-78695); Linker (HY-W040165); Photosensitizer (HY-176725) .
    ZnPc-O3-JQ1
  • HY-149778
    Antifungal agent 87

    		Fungal Infection
    Antifungal agent 87(10) acts as a highly potent PDT antimycotic photosensitizer (PDT-IC50 = 1 nM for T. rubrum) .
    Antifungal agent 87
  • HY-168854
    TBC-1

    		Photosensitizer Reactive Oxygen Species (ROS) Cancer
    TBC-1 is a chlorophyll-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT). TBC-1 efficiently generats Type-I ROS and endoplasmic reticulum targeting ability. TBC-1 shows biocompatibility and PDT efficiency in vitro under both normoxia and hypoxia .
    TBC-1
  • HY-D1673
    Tetrabromorhodamine 123 bromide

    		Fluorescent Dye Cancer
    Tetrabromorhodamine 123 (TBR) bromide is a photosensitizer. Tetrabromorhodamine 123 bromide can be used for the research of photo dynamic therapy (PDT) and cancer .
    Tetrabromorhodamine 123 bromide
  • HY-16477A
    Talaporfin

    ME2906 free acid; Mono-L-aspartyl chlorin e6 free acid; NPe6 free acid

    		 Photosensitizer Cancer
    Talaporfin sodium, can be used in intraoperative photodynamic therapy (PDT) with a 664-nm semiconductor laser, was evaluated for efficacy and safety in treating primary malignant parenchymal brain tumors .
    Talaporfin
  • HY-168097
    Ferroptosis inducer-6

    		Ferroptosis Reactive Oxygen Species (ROS) Cancer
    Ferroptosis inducer 6 (6d) is a ferroptosis inducer with high potency for type I/-II photodynamic therapy by inducing ROS generation, oxidative stress and mitochondrial damage. Ferroptosis inducer 6 has anti-tumor activity .
    Ferroptosis inducer-6
  • HY-13547
    ADPM06

    		Apoptosis Cancer
    ADPM06, a lead candidate azadipyrromethene, is a novel nonporphyrin photodynamic therapeutic (PDT) agent. ADPM06 exhibits IC50 values in the micro-molar range in human tumor cells and induces apoptosis .
    ADPM06
  • HY-168261
    CQ-ER

    		Ferroptosis Cancer
    CQ-ER is a Coumarin (HY-N0709)-Quinazolinone based endoplasmic reticulum (ER)-targeted photosensitizer. CQ-ER can cause ferroptosis, thereby enhancing photodynamic therapy (PDT) .
    CQ-ER
  • HY-157051
    [Ru(DIP)2TAP]Cl2

    		Photosensitizer Cancer
    [Ru(DIP)2TAP]Cl2, Ruthenium(II) polypyridyl compound, is a photosensitizer. [Ru(DIP)2TAP]Cl2 can be used for the research of photodynamic therapy (PDT) .
    [Ru(DIP)2TAP]Cl2
  • HY-151940
    Mal-Pc

    		Reactive Oxygen Species (ROS) Cancer
    Mal-Pc is a versatile molecular photosensitizer designed based phthalocyanine and maleimides. Mal-Pc can react with GSH to deplete GSH and reduce aggregation, thereby improving ROS (Reactive Oxygen Species)-mediated effect of photodynamic therapy (PDT) in cancer cells .
    Mal-Pc
  • HY-19873
    SL-052

    		Photosensitizer Cancer
    SL-052 is a hypocrellin-based photosensitizer that has recently shown promising results in clinical and preclinical testing for cancer photodynamic therapy (PDT). SL-052 is encapsulated in biodegradable polylactic-co-glycolic acid (PLGA) polymer nanoparticles optimized using single emulsion solvent evaporation technology. The SL-052-PLGA nanoparticles were more effective in PDT treatment of subcutaneous SCCVII squamous cell carcinoma compared to polyvinylpyrrolidone (PVP)-based and standard liposomal SL-052 formulations. A longer time interval between drug injection and tumor illumination can improve tumor cure rates, and SL-052-PLGA nanoparticles showed the best therapeutic effect among all SL-052 formulations.
    SL-052
  • HY-W769206
    Talaporfin-13C4,15N

    ME2906 free acid-13C4,15N; Mono-L-aspartyl chlorin e6 free acid-13C4,15N; NPe6 free acid-13C4,15N

    		 Isotope-Labeled Compounds Photosensitizer Cancer
    Talaporfin- 13C4, 15N (ME2906 (free acid)- 13C4, 15N) is the 13C- and 15N-labeled Talaporfin (HY-16477A). Talaporfin sodium, can be used in intraoperative photodynamic therapy (PDT) with a 664-nm semiconductor laser, was evaluated for efficacy and safety in treating primary malignant parenchymal brain tumors .
    Talaporfin-13C4,15N
  • HY-D2620
    CAR-2

    		Photosensitizer Reactive Oxygen Species (ROS) Ferroptosis Cancer
    CAR-2 is a BODIPY-based photosensitizer that induces ferroptosis in photodynamic therapy (PDT) by targeting the endoplasmic reticulum (ER) and lipid droplets (LDs). CAR-2 exhibits phototoxicity in breast cancer cells with IC50 of 0.01-0.02 μM. CAR-2 exhibits antitumor efficacy in 4T1 xenograft mouse models .
    CAR-2
  • HY-128973R
    Pyropheophorbide-a (Standard)

    		Reactive Oxygen Species (ROS) Reference Standards Cancer
    Pyropheophorbide-a (Standard) is the analytical standard of Pyropheophorbide-a. This product is intended for research and analytical applications. Pyropheophorbide-a (Ppa) is a photosensitizer used in photodynamic therapy (PDT) for tumors. Pyropheophorbide-a exhibits phototoxic effects on tumor cells, such as cervical cancer cells, and also has anti-lipogenesis activity. Pyropheophorbide-a shows potential for research in the fields of cancer and age-related macular degeneration (AMD). Pyropheophorbide-a derivatives also demonstrate inhibitory activity against tumor cells .
    Pyropheophorbide-a (Standard)
  • HY-162944
    NA-Ir

    		Ferroptosis Mitochondrial Metabolism STING Autophagy Cancer
    NA-Ir is a Ferroptosis inducer. NA-Ir targets mitochondrial DNA (mtDNA) and activates the cGAS-STING pathway to induce ferritinophagy (Autophagy), while also generating reactive oxygen species (ROS) through photodynamic therapy (PDT), depleting glutathione (GSH), and downregulating glutathione peroxidase 4 (GPX4), thereby triggering lipid peroxidation and Ferroptosis. NA-Ir exhibits higher anticancer activity under light exposure and selectively inhibits cancer cells with high H2S levels .
    NA-Ir
  • HY-161668
    Ru-Poma

    		Ligands for E3 Ligase Ferroptosis Cancer
    Ru-Poma is a Ru(II)-based photosensitizer, which attenuates Cisplatin (HY-17394)-resistant tumor through photodynamic therapy (PDT). Ru-Poma photodegrades CRBN through a Pomalidomide (HY-10984) moiety. Ru-Poma induces ferroptosis, through an increase in lipid peroxide, downregulation of GPX4 and GAPDH expression. Ru-Poma exhibits cytotoxicity in A549, with IC50 of 18.46 μM and 0.37 μM in dark and upon irradiation, respectively .
    Ru-Poma
  • HY-175214
    Antitumor photosensitizer-9

    		Reactive Oxygen Species (ROS) Photosensitizer Cancer
    Antitumor photosensitizer-9 is a near-infrared Photosensitizer (PS) with a high singlet oxygen production rate (relative rate = 1.79). Antitumor photosensitizer-9 exhibits strong phototoxicity against various cancer cells and induces ROS generation under light irradiation. Antitumor photosensitizer-9 inhibits tumor growth in vivo and exhibits excellent anticancer photodynamic therapy (PDT) efficacy at low drug and light doses. Antitumor photosensitizer-9 can be used in photodynamic therapy research .
    Antitumor photosensitizer-9
  • HY-157053
    [Ru(dppn)2phen](PF6)2

    		Biochemical Assay Reagents Cancer
    [Ru(dppn)2phen](PF6)2 (compound 4) is a polypyridylruthenium compound used in photodynamic therapy (PDT). [Ru(dppn)2phen](PF6)2 is normally nontoxic under dark conditions and induces mitochondrial respiratory damage upon light exposure. [Ru(dppn)2phen](PF6)2 exhibits high levels of singlet oxygen quantum yield and phototoxicity against cancer cells .
    [Ru(dppn)2phen](PF6)2
  • HY-N2575R
    Hypocrellin A (Standard)

    		Reference Standards PKC Bacterial Parasite HIV VSV VEGFR Bcl-2 Family Apoptosis Infection Metabolic Disease Cancer
    Hypocrellin A (Standard) is the analytical standard of Hypocrellin A. This product is intended for research and analytical applications. Hypocrellin A is a PKC inhibitor that exerts antidiabetic activity by reversing the effects of high glucose on endothelin (ET-1) expression. Hypocrellin A is also a photosensitizer for photodynamic therapy (PDT) with anticancer, antibacterial and antiviral activities, especially against human immunodeficiency virus (HIV). In addition, Hypocrellin-A also possesses anti-Leishmania activity (IC50=0.27 μg/ml)[1][2][3][4][5][6][7][8][9].
    Hypocrellin A (Standard)
  • HY-163691
    Antitumor agent-163

    		Carbonic Anhydrase Cancer
    Antitumor agent-163 (Compound 3) is a photosensitizer used in Molecular-Targeted Photodynamic Therapy (MT-PDT) targeting carbonic anhydrase IX (CAIX). Antitumor agent-163 inactivates CAIX protein via singlet oxygen under 540 nm wavelength light, without affecting internal standard proteins such as α-tubulin, β-actin, and proliferating cell nuclear antigen (PCNA). Antitumor agent-163 induces cell membrane damage, inhibits cell viability (IC50 is 0.2 and 0.05 μM for A549 and U87MG). Antitumor agent-163 exhibits antitumor efficacy in mouse model .
    Antitumor agent-163

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