97 Results for "

PTH

" in MedChemExpress (MCE) Product Catalog:
Products (97)

97 Results for "PTH" in MCE Product Catalog:

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14
14 Publications Verification
Cat. No.: HY-P0059
CAS No.: 52232-67-4
Synonyms: Human parathyroid hormone-(1-34); hPTH (1-34)
Research Areas:  

Others Cancer

Teriparatide (Human parathyroid hormone-(1-34)) is a PTH1 receptor agonist. Teriparatide (Human parathyroid hormone-(1-34)) can be used for osteoporosis research .
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3
3 Cited Publications
Cat. No.: HY-17613
CAS No.: 870964-67-3
Synonyms: KHK7580
Target:  

CaSR

Research Areas:  

Metabolic Disease

Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .
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3
3 Cited Publications
Cat. No.: HY-P1252
CAS No.: 12583-68-5
Research Areas:  

Metabolic Disease

Parathyroid Hormone (1-34), bovine is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis .
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2
2 Cited Publications
Cat. No.: HY-P1955A
CAS No.: 1334237-71-6
Synonyms: Velcalcetide hydrochloride; AMG 416 hydrochloride; KAI-4169 hydrochloride
Target:  

CaSR

Research Areas:  

Endocrinology

Etelcalcetide hydrochloride (AMG 416 hydrochloride; KAI-4169 hydrochloride) is a synthetic calcimimetic as an activator of the calcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis, which is promising for research in the field of secondary hyperparathyroidism and chronic kidney disease .
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1
1 Cited Publications
Cat. No.: HY-P1852
CAS No.: 277302-47-3
Target:  

Adenylate Cyclase PTHR

Research Areas:  

Neurological Disease

TIP 39, Tuberoinfundibular Neuropeptide is an endogenous PTH2 receptor agonist and antihypertensive agent. TIP 39, Tuberoinfundibular Neuropeptide selectively activates the PTH2 receptor with no activity on the PTH1 receptor, stimulates cAMP production, activates adenylate cyclase, and elevates intracellular calcium levels via mobilization from intracellular stores. TIP 39, Tuberoinfundibular Neuropeptide is highly conserved in humans, mice, and rats. TIP 39, Tuberoinfundibular Neuropeptide is applicable to research related to nociception and inflammation-induced pain .
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1
1 Cited Publications
Cat. No.: HY-P71060
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PTH; Preproparathyroid Hormone; Parathyroid Hormone; Parathyroid Hormone 1; Parathormone; Prepro-PTH; Parathyrin; FIH1; PTH1
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-100856
CAS No.: 1613373-33-3
Purity:  99.67%
Target:  

PTHR

Research Areas:  

Endocrinology

PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1), with no effect on PTH type 2 receptor.
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Cat. No.: HY-P4385
CAS No.: 129622-68-0
Target:  

PTHR

Research Areas:  

Metabolic Disease

(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) is a potent PTH-1R antagonist and does not display any partial agonist activity .
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Cat. No.: HY-P2426
CAS No.: 118102-98-0
Research Areas:  

Metabolic Disease

(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) is a potent and competitive antagonist of parathyroid hormone (PTH), with a Ki of 69 nM in bovine renal cortical membrane. (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) can be used for growth and development regulation .
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Cat. No.: HY-P4821
CAS No.: 83139-29-1
Research Areas:  

Metabolic Disease Cancer

PTH (1-34) amide human is a type 1 PTH/PTHrP receptor agonist. PTH (1-34) amide human activates adenylate cyclase and phospholipase C pathways, thereby mediating mineral ion homeostasis and bone metabolism regulation. PTH (1-34) amide human increases serum calcium, decreases serum phosphorus, regulates renal excretion, while inducing the inhibition of endogenous PTH (1-84) and the increase of 1,25-dihydroxyvitamin D2 and bone resorption. PTH (1-34) amide human stimulates phosphatidylcholine hydrolysis via phospholipase D mediation, and its hypercalcemic effect is inhibited by human PTH-(7-84). PTH (1-34) amide human can be used in the research of diseases related to humoral hypercalcemia of malignancy .
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Cat. No.: HY-P4823
CAS No.: 136799-54-7
Target:  

Adenylate Cyclase PTHR

Research Areas:  

Metabolic Disease

PTH (1-37) human is an adenylate cyclase stimulator and a normocalcemic regulator. PTH (1-37) human participates in cAMP-dependent signal transduction to affect the proliferation of skeletal tissue cells and bone metabolism. PTH (1-37) human induces cyclic adenosine monophosphate responses in human primary osteoblast-like cells and is also widely used in osteoporosis-related research .
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Cat. No.: HY-P10909
CAS No.: 2925554-87-4
Synonyms: MBX 2109
Target:  

PTHR Drug Intermediate

Research Areas:  

Endocrinology

Canvuparatide (MBX 2109) is a PTH analog prodrug that releases the biologically active peptide through temperature- and pH-controlled intramolecular cyclization. The peptide released by Canvuparatide binds to and activates the PTH1 receptor, stimulating dose-dependent cAMP accumulation. Canvuparatide can be used in research on hypoparathyroidism .
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Cat. No.: HY-P10277
CAS No.: 2222514-07-8
Synonyms: Transcon PTH; ACP-014
Target:  

Inhibitory Antibodies

Research Areas:  

Endocrinology

Palopegteriparatide (Transcon PTH) is a prodrug of parathyroid hormone PTH 1-34, which can maintain normal and stable calcium concentrations without the need for calcium and active vitamin D replacement. Palopegteriparatide can be used in research on hypoparathyroidism .
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Cat. No.: HY-P4825
CAS No.: 78232-94-7
Target:  

Inhibitory Antibodies

Research Areas:  

Others

pTH (1-38) (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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Cat. No.: HY-P3075
CAS No.: 112540-82-6
Synonyms: PTHrP (1-34)
pTH-Related Protein (1-34) (human,mouse,rat) (pTHrP (1-34)) is a parathyroid hormone-related protein fragment. Binding of pTH-Related Protein (1-34) (human,mouse,rat) to PTH1R triggers cAMP/PKA and PKC signaling, PI3K-mediated Akt and ERK1/2 phosphorylation, NADPH oxidase-dependent ROS generation, and TGF-beta1 and p47phox expression. pTH-Related Protein (1-34) (human,mouse,rat) induces fibronectin upregulation, osteoblast differentiation, osteoclastic bone resorption, bone formation, eNOS/NO-mediated vasodilation, and sensitization of type II pneumocytes to ultraviolet-induced apoptosis (apoptosis) via caspase 3. pTH-Related Protein (1-34) (human,mouse,rat) can be used in research on diabetic nephropathy, breast cancer, acute lung injury, humoral hypercalcemia of malignancy, osteoporosis, and cartilage degeneration .
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Cat. No.: HY-P4697A
Research Areas:  

Endocrinology

pTH (44-68) (human) TFA is a fragment of human parathyroid hormone (pTH) that lacks the adenylate cyclase-stimulating activity of intact pTH. pTH (44-68) (human) TFA can be used to study the mechanism of action of pTH .
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Cat. No.: HY-P10078
CAS No.: 90880-43-6
Research Areas:  

Endocrinology

pTH (39-84) (human) is the C-terminal fragment of parathyroid hormone (PTH). pTH (39-84) (human) increases Apoptosis. pTH (39-84) (human) can stimulate osteoclast formation .
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Cat. No.: HY-P1418A
Research Areas:  

Endocrinology

DPC-AJ1951 TFA, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). And characterized the activity of DPC-AJ1951 TFA in ex vivo and in vivo assays of bone resorption .
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Cat. No.: HY-17613R
CAS No.: 870964-67-3
Synonyms: KHK7580 (Standard)
Research Areas:  

Metabolic Disease

Evocalcet (Standard) is the analytical standard of Evocalcet. This product is intended for research and analytical applications. Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .
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Cat. No.: HY-P1955
CAS No.: 1262780-97-1
Synonyms: Velcalcetide; AMG 416; KAI-4169
Target:  

CaSR

Research Areas:  

Metabolic Disease

Etelcalcetide (AMG 416; KAI-4169) is a synthetic calcimimetic as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis, which is promising for research in the field of secondary hyperparathyroidism and chronic kidney disease .
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