89 Results for "

Traditional Chinese medicine

" in MedChemExpress (MCE) Product Catalog:
Products (89)

89 Results for "Traditional Chinese medicine" in MCE Product Catalog:

11
Physcion
Physcion
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11 Publications Verification
Cat. No.: HY-N0108
CAS No.: 521-61-9
Synonyms: Parietin; Rheochrysidin
Category:  

Polygonaceae Marine natural products Plants Biological Pesticide Research Agricultural Research Infection Quinones Microorganisms Anthraquinones Rheum officinale Baill. Phenols Polyphenols Disease Research Fields Inflammation/Immunology Marine microorganism Cancer

Target:  

Bacterial Toll-like Receptor (TLR) NF-κB Apoptosis Autophagy Antibiotic

Physcion (Parietin), an anthraquinone derivative derived from the traditional Chinese medicine rhubarb, is an effective oral active 6-phosphogluconate dehydrogenase inhibitor with blood-brain barrier permeability, with IC50 and Kd values of 38.5 μM and 26.0 μM, respectively. Additionally, Physcion is an inhibitor of the <>bTLR4/NF-κB signaling pathway, exhibiting anti-inflammatory, antibacterial, and anticancer effects, and can induce Apoptosis and Autophagy in cancer cells .
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8
Homoplantaginin
Homoplantaginin
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8 Cited Publications
Cat. No.: HY-N1949
CAS No.: 17680-84-1
Category:  

Flavonoids Flavones Labiatae Cassia Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Free Radical Scavengers TNF Receptor NF-κB

Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia with antiinflammatory and antioxidant properties. Homoplantaginin could inhibit TNF-α and IL-6 mRNA expression, IKKβ and NF-κB phosphorylation.
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7
Oroxin B
Oroxin B
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7 Cited Publications
Cat. No.: HY-N1435
CAS No.: 114482-86-9
Category:  

Flavonoids Flavones Phenols Polyphenols Plants Bignoniaceae Oroxylum indicum (Linn.) Bentham ex Kurz Disease Research Fields Cancer

Target:  

Apoptosis PI3K PTEN Autophagy

Oroxin B (OB) is a BBB-permeable flavonoid isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent. Oroxin B (OB) possesses obvious inhibitory effect and induces early apoptosis rather than late apoptosis on liver cancer cells through upregulation of PTEN, down regulation of COX-2, VEGF, PI3K, and p-AKT. Oroxin B (OB) selectively induces tumor-suppressive ER stress in malignant lymphoma cells .
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5
Mogroside V
Mogroside V
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5 Cited Publications
Cat. No.: HY-N0502
CAS No.: 88901-36-4
Category:  

Triterpenes Terpenoids Cucurbitaceae Metabolic Disease Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Disease Research Fields Sweeteners Food Research

Target:  

Reactive Oxygen Species (ROS)

Mogroside V is a the major active constituent of a traditional Chinese medicine Siraitiae Fructus. Mogroside V reduces the intracellular reactive oxygen species (ROS) levels and enhances mitochondrial function. Mogroside V has anti-oxidative, anti-diabetic and anti-carcinogenic effects. Mogroside V can be used for diabetic diseases research .
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5
Nicotiflorin
Nicotiflorin
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5 Cited Publications
Cat. No.: HY-N1475
CAS No.: 17650-84-9
Category:  

Flavonols Flavonoids Carthamus tinctorius L. Phenols Polyphenols Plants Compositae

Target:  

Others

Nicotiflorin is a flavonoid glycoside extracted from a traditional Chinese medicine Carthamus tinctorius. Nicotiflorin shows potent antiglycation activity and neuroprotection effects.
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4
Danthron
Danthron
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4 Cited Publications
Cat. No.: HY-B0923
CAS No.: 117-10-2
Synonyms: Dantron; Chrysazin; 1,8-Dihydroxyanthraquinone
Category:  

Quinones Labiatae Anthraquinones Samanea saman (Jacq.) Merr. Phenols Polyphenols Plants Disease Research Fields Cancer

Target:  

AMPK Autophagy Bacterial Virus Protease

Danthron is a natural product extracted from the traditional Chinese medicine Salvia miltiorrhiza Bunge. Danthron functions in regulating glucose and lipid metabolism by activating AMPK.
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4
Muscone
Muscone
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4 Cited Publications
Cat. No.: HY-N0633
CAS No.: 541-91-3
Category:  

Cardiovascular Disease Animals Ketones, Aldehydes, Acids Disease Research Fields

Target:  

Environmental Pollutants TNF Receptor P-glycoprotein NF-κB NOD-like Receptor (NLR) Interleukin Related

Muscone is the main active monomer of traditional Chinese medicine musk. Muscone inhibits NF-κB and NLRP3 inflammasome activation. Muscone remarkably decreases the levels of inflammatory cytokines (IL-1β, TNF-α and IL-6), and ultimately improves cardiac function and survival rate .
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4
Anemarrhenasaponin I
Anemarrhenasaponin I
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4 Cited Publications
Cat. No.: HY-N4213
CAS No.: 163047-21-0
Category:  

Cardiovascular Disease Liliaceae Anemarrhena asphodeloides Bunge Plants Disease Research Fields Steroids

Target:  

Others

Anemarrhenasaponin I, a traditional Chinese medicine, shows remarkable inhibiting effect on platelet aggregation.
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3
Ajugol
Ajugol
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3 Cited Publications
Cat. No.: HY-N0914
CAS No.: 52949-83-4
Category:  

Erythrophleum fordii Oliv. Iridoids Labiatae Terpenoids Other Diseases Scrophulariaceae Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey Disease Research Fields

Target:  

Parasite Autophagy Interleukin Related Reactive Oxygen Species (ROS) mTOR

Ajugol is an orally active iridoid glycoside found in the traditional Chinese medicine Leonurus japonicus. Ajugol is an autophagy activator. Ajugol activates TFEB-mediated autophagy and lysosomal biogenesis. Ajugol also has anti-inflammatory effects. Ajugol has great potential in the research of asthma, non-alcoholic fatty liver disease (NAFLD), and osteoarthritis .
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3
Safflower yellow
Safflower yellow
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3 Cited Publications
Cat. No.: HY-N0938
CAS No.: 1401-20-3
Category:  

Natural Products Carthamus tinctorius L. Other Diseases Plants Compositae Disease Research Fields

Target:  

Fluorescent Dye

Safflower yellow is extracted from the flowers of the plant safflower (Carthamus tinctorius) and as the traditional Chinese medicine it has been extensively used for the treatment of cardio cerebrovascular diseases.
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2
Anisodamine
Anisodamine
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2 Cited Publications
Cat. No.: HY-N0584
CAS No.: 55869-99-3
Synonyms: 6-Hydroxyhyoscyamine
Category:  

Alkaloids Neurological Disease Other Alkaloids Anisodus tanguticus (Maxinowicz) Pascher Plants Solanaceae Disease Research Fields

Target:  

mAChR

Anisodamine (6-Hydroxyhyoscyamine), a belladonna alkaloid, is a non-subtype-selective muscarinic, and also a nicotinic cholinoceptor antagonist. Anisodamine employs in traditional Chinese medicine for many ailments, mainly to improve the microcirculation in states of shock, and also in organophosphate poisoning .
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2
Nicotiflorin (Standard)
Nicotiflorin (Standard)
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2 Cited Publications
Cat. No.: HY-N1475R
CAS No.: 17650-84-9
Category:  

Flavonols Flavonoids Carthamus tinctorius L. Phenols Polyphenols Plants Compositae

Target:  

Reference Standards Others

Nicotiflorin (Standard) is the analytical standard of Nicotiflorin. This product is intended for research and analytical applications. Nicotiflorin is a flavonoid glycoside extracted from a traditional Chinese medicine Carthamus tinctorius. Nicotiflorin shows potent antiglycation activity and neuroprotection effects.
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1
Benzoylaconine
Benzoylaconine
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1 Cited Publications
Cat. No.: HY-N0217
CAS No.: 466-24-0
Synonyms: Benzoylaconitine; Isaconitine; Pikraconitin
Category:  

Alkaloids Other Alkaloids Ranunculaceae Other Diseases  Aconitum carmichaeli Debx. Plants Disease Research Fields

Target:  

Angiotensin-converting Enzyme (ACE) Reactive Oxygen Species (ROS) Toll-like Receptor (TLR) NF-κB COX NO Synthase p38 MAPK P-glycoprotein

Benzoylaconine (Benzoylaconitine) is an orally active monoester alkaloid found in the traditional Chinese medicine Aconitum carmichaelii. Benzoylaconine is an ACE2 agonist (EC50: 1.5 μM) with antihypertensive and anti-heart failure effects. Benzoylaconine inhibits TLR-induced MAPK and NF-κB pathways to exert anti-inflammatory effects. Benzoylaconine upregulates the protein levels of P-gp, MRP2, and has anti-tumor effects .
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1
Cyclovirobuxine D
Cyclovirobuxine D
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1 Cited Publications
Cat. No.: HY-N0107
CAS No.: 860-79-7
Category:  

Cardiovascular Disease Alkaloids Buxaceae Other Alkaloids Plants Disease Research Fields Buxus microphylla S.et Z.var. Sinica Rehd.et Wils.

Target:  

Apoptosis Autophagy mTOR Akt

Cyclovirobuxine D (CVB-D) is the main active component of the traditional Chinese medicine Buxus microphylla. Cyclovirobuxine D induces autophagy and attenuates the phosphorylation of Akt and mTOR . Cyclovirobuxine D inhibits cell proliferation of gastric cancer cells through suppression of cell cycle progression and inducement of mitochondria-mediated apoptosis . Cyclovirobuxine D is beneficial for heart failure induced by myocardial infarction .
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Darutoside
Darutoside
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1 Cited Publications
Cat. No.: HY-N6028
CAS No.: 59219-65-7
Category:  

Terpenoids Diterpenoids Plants Compositae Disease Research Fields Tephrosia candida DC. Inflammation/Immunology

Target:  

COX NF-κB Interleukin Related TNF Receptor

Darutoside is an orally effective diterpene compound with significant anti-inflammatory, analgesic, wound healing promotion, and immunomodulatory activities. Darutoside reduces edema and pain responses by inhibiting the expression of COX-2 and the migration of inflammatory cells. It regulates macrophage polarization towards the M2 type by inhibiting the NF-κB pathway, alleviating inflammation and promoting wound healing. Through multi-target regulation of metabolic networks, Darutoside significantly alleviates acute gouty arthritis .
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1
Smilagenin
Smilagenin
0 Images
1 Cited Publications
Cat. No.: HY-106353
CAS No.: 126-18-1
Purity:  ≥98.0%
Category:  

Pelargonium hortorum Bailey Liliaceae Neurological Disease Anemarrhena asphodeloides Bunge Plants Disease Research Fields Geraniaceae Steroids

Target:  

mAChR Endogenous Metabolite

Smilagenin (SMI) is a small-molecule steroidal sapogenin from Anemarrhena asphodeloides and Pelargonium hortorum widely used in traditional Chinese medicine for treating chronic neurodegeneration diseases . Smilagenin (SMI) improves memory of aged rats by increasing the muscarinic receptor subtype 1 (M1)-receptor density . Smilagenin (SMI) attenuates Aβ(25-35)-induced neurodegenerationvia stimulating the gene expression of brain-derived neurotrophic factor, may represents a novel therapeutic strategy for AD .
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Guaiol
Guaiol
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1 Cited Publications
Cat. No.: HY-N3980
CAS No.: 489-86-1
Synonyms: Champacol; Guaiac alcohol
Category:  

Infection Terpenoids Sesquiterpenes Distemonanthus benthamianus Baill. Plants Compositae Disease Research Fields

Target:  

Autophagy RAD51

Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions [4]
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Skimmin
Skimmin
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1 Cited Publications
Cat. No.: HY-N2263
CAS No.: 93-39-0
Synonyms: Umbelliferone glucoside
Category:  

Polygalaceae Polygala japonica Houtt. Coumarins Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology

Target:  

Interleukin Related TGF-β Receptor TNF Receptor Parasite

Skimmin (Umbelliferone glucoside) is a major pharmacologically active and orally active molecule present in Hydrangea paniculata, a medical herb used in traditional Chinese medicine as an anti-inflammatory agent. Skimmin has renal protective activity. Skimmin can improve creatinine clearance, and reduce plasma creatinine, and kidney injuries. Skimmin has good anti-amoebic activity against the HM1:IMMS strain of Entamoeba histolytica. Skimmin has anti-cancer and neuroprotective activities. Skimmin reduces cardiac fibrosis as well as decreasing TNF-α, IL-6, IL1β, and TGFβ1 in cardiac tissues. Skimmin can be studied in research for diabetes and diabetes-related diseases .
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Sennoside C
Sennoside C
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1 Cited Publications
Cat. No.: HY-N1972
CAS No.: 37271-16-2
Category:  

Quinones Leguminosae Anthraquinones Other Diseases Phenols Polyphenols Plants Cassia angustifolia Disease Research Fields

Target:  

Others

Sennoside C is an orally active component of the traditional Chinese medicine Sennae Folium. Sennoside C can bind to human lysozyme and inhibit its amyloid fibrosis (IC50: 186.20 μM). Sennoside C has certain purgative activity. Sennoside C can be used in the research of diarrhea and anti-amyloid related diseases .
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Glaucocalyxin B
Glaucocalyxin B
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1 Cited Publications
Cat. No.: HY-N2113
CAS No.: 80508-81-2
Category:  

Labiatae Terpenoids Sesquiterpenes Plants Glycyrrhiza lepidota Pursh Disease Research Fields Cancer

Target:  

Autophagy

Glaucocalyxin B is an ent kaurane diterpenoid isolated from the Chinese traditional medicine Rabdosia japonica with anticancer and antitumor activity; decreases the growth of HL-60 cells with an IC50 of approximately 5.86 μM at 24 h.
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