294 Results for "

Tryptophan

" in MedChemExpress (MCE) Product Catalog:
Products (294)

294 Results for "Tryptophan" in MCE Product Catalog:

30
30 Publications Verification
Cat. No.: HY-104026
CAS No.: 2922-83-0
Purity:  99.93%
L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.
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27
27 Cited Publications
Cat. No.: HY-B1368
CAS No.: 7424-00-2
Synonyms: 4-Chloro-DL-phenylalanine; PCPA; CP-10188
Research Areas:  

Neurological Disease Cancer

Fenclonine is a selective and irreversible tryptophan hydroxylase inhibitor, which is a rate-limiting enzyme in the biosynthesis of serotonin. Fenclonine can be used in carcinoid syndrome research .
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27
27 Cited Publications
Cat. No.: HY-W772850
CAS No.: 23633-07-0
Synonyms: 4-Chloro-DL-phenylalanine hydrochloride; PCPA hydrochloride; CP-10188 hydrochloride
Research Areas:  

Neurological Disease Cancer

Fenclonine hydrochloride is a selective and irreversible tryptophan hydroxylase inhibitor, which is a rate-limiting enzyme in the biosynthesis of serotonin. Fenclonine hydrochloride can be used in carcinoid syndrome research .
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17
17 Cited Publications
Cat. No.: HY-N0623
CAS No.: 73-22-3
Synonyms: Tryptophan; Tryptophane
L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels .
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16
16 Cited Publications
Cat. No.: HY-113099
CAS No.: 1821-52-9
Purity:  99.99%
Synonyms: Indole-3-lactic acid
Indolelactic acid (Indole-3-lactic acid) is a tryptophan (Trp) catabolite in Azotobacter vinelandii cultures. Indolelactic acid has anti-inflammation and potential anti-viral activity .
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14
14 Cited Publications
Cat. No.: HY-13642
CAS No.: 48208-26-0
Purity:  99.93%
Synonyms: N-Phthalyl-L-Tryptophan
Target:  

DNA Methyltransferase

Research Areas:  

Inflammation/Immunology Cancer

RG108 (N-Phthalyl-L-tryptophan) is a non-nucleoside DNA methyltransferases (DNMTs) inhibitor (IC50=115 nM) that blocks the DNMTs active site. RG108 (N-Phthalyl-L-tryptophan) causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences .
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11
11 Cited Publications
Cat. No.: HY-16724
CAS No.: 110117-83-4
Synonyms: 1-Methyl-D-Tryptophan; NLG-8189
Research Areas:  

Cancer

Indoximod (1-Methyl-D-tryptophan) is an orally active indoleamine 2,3-dioxygenase (IDO) pathway inhibitor. Indoximod acts as a Trp mimetic in regulating mTOR. Indoximod is an immunometabolic adjuvant used for the research of cancer .
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11
11 Cited Publications
Cat. No.: HY-100806
CAS No.: 492-27-3
Purity:  99.21%
Synonyms: Quinurenic acid
Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8.
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11
11 Cited Publications
Cat. No.: HY-107512
CAS No.: 2439-02-3
Purity:  99.79%
Kynurenic acid sodium, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid sodium is also an agonist of GPR35/CXCR8.
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7
7 Cited Publications
Cat. No.: HY-100807
CAS No.: 89-00-9
Purity:  99.85%
Quinolinic acid, an endogenous metabolite of tryptophan, is a N-methyl-D-aspartate receptor (NMDA receptor) agonist. Quinolinic acid increases glutamate efflux, induces the generation of ROS, activates nitric oxide synthase, produces excessive NO, leading to calcium ion influx and neuronal apoptosis .
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6
6 Cited Publications
Cat. No.: HY-15849
CAS No.: 945976-43-2
Purity:  98.02%
LP-533401 is a Tryptophan hydroxylase 1 inhibitor that regulates serotonin production in the gut.
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6
6 Cited Publications
Cat. No.: HY-15849A
CAS No.: 1040526-12-2
Purity:  98.02%
LP-533401 hydrochloride is a tryptophan hydroxylase 1 inhibitor that regulates serotonin production in the gut.
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5
5 Cited Publications
Cat. No.: HY-77839
CAS No.: 152-58-9
Synonyms: 11-Deoxycortisol; cortexolone; Reichstein's substance S
Cortodoxone (11-Deoxycortisol; cortexolone) is a glucocorticoid steroid hormone and also is a glucocorticoid antagonist. Cortodoxone increases tryptophan oxygenase (TO) activity and induces the secretion of corticosterone. Cortodoxone regulates T cell proliferation and activation .
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5
5 Cited Publications
Cat. No.: HY-13055A
CAS No.: 1033805-22-9
Purity:  99.79%
Synonyms: LX1032; LX1606
Research Areas:  

Neurological Disease Cancer

Telotristat ethyl (LX1032) is a novel, orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.
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5
5 Cited Publications
Cat. No.: HY-13055
CAS No.: 1137608-69-5
Purity:  99.89%
Synonyms: LX1606 Hippurate
Research Areas:  

Neurological Disease Cancer

Telotristat etiprate (LX1606 Hippurate) is a novel, orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.
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5
5 Cited Publications
Cat. No.: HY-101456
CAS No.: 14173-40-1
Purity:  99.89%
Synonyms: 4-Chloro-DL-phenylalanine methyl ester hydrochloride
PCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride), a reversible tryptophan hydroxylase inhibitor, is a serotonin (5-HT) synthesis inhibitor. PCPA methyl ester hydrochloride crosses the blood brain barrier and reduces 5-HT central availability .
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3
3 Cited Publications
Cat. No.: HY-N0623S
CAS No.: 62595-11-3
Synonyms: Tryptophan-d5; Tryptophane-d5
L-Tryptophan-d5 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .
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3
3 Cited Publications
Cat. No.: HY-W028393
CAS No.: 392-12-1
Indole-3-pyruvic acid, a keto analogue of tryptophan, is an orally active AHR agonist. Indole-3-pyruvic acid has antioxidant properties, and can be used in the research of inflammation, anxiety .
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2
2 Cited Publications
Cat. No.: HY-108681
CAS No.: 163239-22-3
Purity:  99.54%
680C91 is an orally active, selective tryptophan 2,3-dioxygenase (TDO) inhibitor with a Ki of 51 nM. TDO is the key enzyme of tryptophan catabolism. 680C91 can be used for the research of cancer immunotherapy and Alzheimer’s Disease .
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2
2 Cited Publications
Cat. No.: HY-N0623R
CAS No.: 73-22-3
Synonyms: Tryptophan (standard); Tryptophane (standard)
L-Tryptophan (standard) is the analytical standard of L-Tryptophan. L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels .
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