817 Results for "

biologically active

" in MedChemExpress (MCE) Product Catalog:
Products (817)

817 Results for "biologically active" in MCE Product Catalog:

43
Niclosamide
Niclosamide
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43 Publications Verification
Referencia número: HY-B0497
No. CAS: 50-65-7
Synonyms: BAY2353
Target:  

Environmental Pollutants Antibiotic Parasite STAT

Áreas de investigación:  

Infection Cancer

Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research . Niclosamide is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells . Niclosamide has biological activities against cancer, inhibits DNA replication in Vero E6 cells .
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43
Niclosamide olamine
Niclosamide olamine
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43 Publications Verification
Referencia número: HY-B0497C
No. CAS: 1420-04-8
Synonyms: BAY2353 olamine
Target:  

Environmental Pollutants Antibiotic STAT Parasite

Áreas de investigación:  

Infection Cancer

Niclosamide (BAY2353) olamine is an orally active antihelminthic agent used in parasitic infection research . Niclosamide olamin is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells . Niclosamide olamin has biological activities against cancer, and inhibits DNA replication in Vero E6 cells .
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17
Arctigenin
Arctigenin
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17 Cited Publications
Referencia número: HY-N0035
No. CAS: 7770-78-7
Synonyms: (-)-Arctigenin
Category:  

Neurological Disease Anti-aging Lignans Metabolic Disease Plants Compositae Caesalpinia magnifoliolata Metc. Endogenous metabolite Infection Human Gut Microbiota Metabolites Phenylpropanoids Disease Research Fields Inflammation/Immunology Cancer

Target:  

MMP Influenza Virus Autophagy Apoptosis

Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions .
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14
[6]-Gingerol
[6]-Gingerol
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14 Cited Publications
Referencia número: HY-14615
No. CAS: 23513-14-6
Pureza:  99.68%
Synonyms: (S)-(+)-[6]Gingerol
Category:  

Zingiber officinale Roscoe Monophenols Phenols Plants Disease Research Fields Cancer Zingiberaceae

Target:  

AMPK Apoptosis

[6]-Gingerol is an active compound isolated from Ginger (Zingiber officinale), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.
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14
L-Thyroxine
L-Thyroxine
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14 Cited Publications
Referencia número: HY-18341
No. CAS: 51-48-9
Synonyms: Levothyroxine; T4
Category:  

Endocrine diseases Endogenous metabolite Immune System Disorder Monophenols Ketones, Aldehydes, Acids Disease markers Phenols Nervous System Disorder Disease Research Fields Endocrinology

Target:  

Thyroid Hormone Receptor Endogenous Metabolite

L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .
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13
Shogaol
Shogaol
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13 Cited Publications
Referencia número: HY-14616
No. CAS: 555-66-8
Pureza:  99.63%
Synonyms: [6]-Shogaol; 6-Shogaol
Category:  

Zingiber officinale Roscoe Monophenols Phenols Plants Disease Research Fields Cancer Zingiberaceae

Target:  

Autophagy

Shogaol ([6]-Shogaol), an active compound isolated from Ginger (Zingiber officinale Rosc), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.
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13
L-Thyroxine sodium
L-Thyroxine sodium
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13 Cited Publications
Referencia número: HY-18341B
No. CAS: 55-03-8
Synonyms: Levothyroxine sodium; T4 sodium
Category:  

Natural Products Endogenous metabolite Disease Research Fields Endocrinology Cancer

Target:  

Thyroid Hormone Receptor Endogenous Metabolite

L-Thyroxine sodium (Levothyroxine sodium) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .
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13
L-Thyroxine sodium salt pentahydrate
L-Thyroxine sodium salt pentahydrate
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13 Cited Publications
Referencia número: HY-18341A
No. CAS: 6106-07-6
Synonyms: Sodium levothyroxine pentahydrate
Category:  

Natural Products Endogenous metabolite Disease Research Fields Endocrinology Cancer

Target:  

Thyroid Hormone Receptor Endogenous Metabolite

L-Thyroxine sodium salt pentahydrate (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .
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12
L-Cysteine
L-Cysteine
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12 Cited Publications
Referencia número: HY-Y0337
No. CAS: 52-90-4
Synonyms: Cysteine
Category:  

Human Gut Microbiota Metabolites Microorganisms Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields

Target:  

Environmental Pollutants Endogenous Metabolite

L-Cysteine (Cysteine) is an orally active conditionally essential amino acid with hypoglycemic effects, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine promotes the proliferation and differentiation of neural stem cells via the CBS/H2S pathway. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans. L-Cysteine can be used as an anorectic agent .
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12
L-Cysteine hydrochloride
L-Cysteine hydrochloride
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12 Cited Publications
Referencia número: HY-Y0337A
No. CAS: 52-89-1
Category:  

Anti-aging Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

L-Cysteine hydrochloride is an orally active conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) .
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12
L-Cysteine hydrochloride hydrate
L-Cysteine hydrochloride hydrate
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12 Cited Publications
Referencia número: HY-W016715
No. CAS: 7048-04-6
Category:  

Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite NF-κB Insulin Receptor

L-Cysteine hydrochloride hydrate is an orally active and essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride hydrate regulates CBS/H2S pathway, inhibits NF-κB activation and insulin and ghrelin secretion. L-Cysteine hydrochloride hydrate reduces blood sugar, vascular inflammation markers and appetite. L-Cysteine hydrochloride hydrate induces kidney damage. L-Cysteine hydrochloride hydrate can be used in the study of neurological diseases and diabetes .
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11
L-Thyroxine sodium xhydrate
L-Thyroxine sodium xhydrate
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11 Cited Publications
Referencia número: HY-W010669
No. CAS: 25416-65-3
Synonyms: Sodium levothyroxine
L-Thyroxine sodium xhydrate (Levothyroxine; T4) is a synthetic hormone in the treatment of hypothyroidism. DIO enzymes convert biologically active hormone (Triiodothyronine,T3) from L-Thyroxine (T4).
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10
Riboflavin
Riboflavin
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10 Cited Publications
Referencia número: HY-B0456
No. CAS: 83-88-5
Synonyms: Vitamin B2; E101
Category:  

Human Gut Microbiota Metabolites Natural Products Microorganisms Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Environmental Pollutants Endogenous Metabolite Bacterial

Riboflavin, an orally active and easily absorbed micronutrient, is a precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which serve as coenzymes for numerous enzymatic reactions and perform key metabolic functions by mediating the transfer of electrons in biological oxidation-reduction reaction .
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9
Phosphoramide mustard cyclohexanamine
Phosphoramide mustard cyclohexanamine
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9 Cited Publications
Referencia número: HY-137316A
No. CAS: 1566-15-0
Pureza:  ≥98.0%
Target:  

DNA Alkylator/Crosslinker Drug Metabolite

Áreas de investigación:  

Cancer

Phosphoramide mustard cyclohexanamine is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA damage .
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9
Lentinan
Lentinan
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9 Cited Publications
Referencia número: HY-N6653
No. CAS: 37339-90-5
Category:  

Polysaccharides Agaricaceae Lentinus edodes (Berk. ) Sing Plants Disease Research Fields Saccharides Cancer

Target:  

JAK Keap1-Nrf2 Apoptosis

Lentinan is an orally active biocompatible multifunctional polysaccharide with biological activities such as anti-inflammatory, antioxidant, immune regulation, anti-tumor, hypoglycemic, and lipid-lowering [1][4].
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8
Fucoidan
Fucoidan
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8 Cited Publications
Referencia número: HY-132179
No. CAS: 9072-19-9
Pureza:  ≥98.0%
Category:  

Brown seaweed Whitening Agent Marine natural products Metabolic Disease Plants other families Polysaccharides Marine algae Cosmetic Research Disease Research Fields Saccharides Cancer

Target:  

Glycosidase

Fucoidan, a biologically active polysaccharide, is an efficient inhibitor of α-amylase and α-glucosidase. Anticoagulant, antitumor, antioxidant and antisteatotic activities .
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7
Quinine
Quinine
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7 Cited Publications
Referencia número: HY-D0143
No. CAS: 130-95-0
Category:  

Infection Cinchona succirubra Pav. ex Klotzsch Alkaloids Rubiaceae Quinoline Alkaloids Plants Disease Research Fields

Target:  

Parasite Potassium Channel Dengue Virus Flavivirus

Quinine is an orally active alkaloid extracted from cinchona bark, possessing various biological activities including antimalarial, antidengue virus (DENV), and anticancer properties. Quinine is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM .
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7
Quinine dihydrochloride
Quinine dihydrochloride
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7 Cited Publications
Referencia número: HY-D0143A
No. CAS: 60-93-5
Category:  

Cinchona succirubra Pav. ex Klotzsch Alkaloids Piperidine Alkaloids Rubiaceae Plants Isoquinoline Alkaloids

Target:  

Parasite Potassium Channel Dengue Virus Flavivirus

Quinine dihydrochloride is an orally active alkaloid extracted from cinchona bark, possessing various biological activities including antimalarial, antidengue virus (DENV), and anticancer properties. Quinine dihydrochloride is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM .
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7
Quinine hemisulfate hydrate
Quinine hemisulfate hydrate
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7 Cited Publications
Referencia número: HY-D0143B
No. CAS: 207671-44-1
Category:  

Infection Alkaloids Rubiaceae Cinchona calisaya Wedd. Quinoline Alkaloids Plants Disease Research Fields

Target:  

Parasite Potassium Channel Dengue Virus Flavivirus

Quinine hemisulfate hydrate is an orally active alkaloid extracted from cinchona bark, possessing various biological activities including antimalarial, antidengue virus (DENV), and anticancer properties. Quinine hemisulfate hydrate acts as a potassium channel inhibitor that suppresses the +100 mV current of MT mSlo3 (KCa5.1) channels induced by voltage pulses, with an IC50 value of 169 μM. Quinine hemisulfate hydrate serves as a fluorescence standard reference substance with fluorescence spectrum calibration and validation activity .
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6
Tetrahydrofolic acid
Tetrahydrofolic acid
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6 Cited Publications
Referencia número: HY-14520
No. CAS: 135-16-0
Pureza:  96.77%
Synonyms: L-5,6,7,8-Tetrahydrofolic acid; L-Tetrahydrofolic acid
Category:  

Human Gut Microbiota Metabolites Microorganisms Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Tetrahydrofolic acid (L-5,6,7,8-Tetrahydrofolic acid) is the biologically active vitamin B9 folate derivative. Tetrahydrofolic acid is a donor of one-carbon groups for amino acids, nucleic acids, and lipids. Tetrahydrofolic acid serves as an acceptor of free formaldehyde, producing 5,10-methylenetetrahydrofolate-Tetrahydrofolic acid .
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