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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
80 Results for "
curcumin
" in MedChemExpress (MCE) Product Catalog:
Products (80)
80 Results for "curcumin" in MCE Product Catalog:
138
138 Publications Verification
Synonyms: Diferuloylmethane; Natural Yellow 3; Turmeric yellow
6
6 Cited Publications
Cat. No.: HY-N0006
CAS No.: 22608-11-3
Synonyms: curcumin II; Desmethoxycurcumin; Monodemethoxycurcumin
5
5 Cited Publications
Cat. No.: HY-N0007
CAS No.: 33171-05-0
Synonyms: (E,E)-curcumin III; (E,E)-Didemethoxycurcumin
3
3 Cited Publications
Synonyms: Diferuloylmethane (Standard); Natural Yellow 3 (Standard); Turmeric yellow (Standard)
2
2
2 Cited Publications
Research Areas:
EF24, a curcumin analogue, is an NF-kB inhibitor with great anti-tumor efficacy and oral bioavailability via deactivation of the MAPK/ERK signaling pathway in oral squamous cell carcinoma (OSCC). EF24 is active against melanoma and breast cancer cell lines with GI50 values of 0.7 μM and 0.8 μM, respectively. EF24 induces cell cycle arrest and apoptosis in MDA-MB-231 human breast cancer cells and DU-145 human prostate cancer cells. EF24 increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK .
1
Category:
Natural Products Red seaweeds Plants Other Families Extract Disease Research Fields Inflammation/Immunology Cancer
Target:
1
1
1 Cited Publications
Cat. No.: HY-W010056
CAS No.: 623-91-6
Target:
1
1 Cited Publications
Cat. No.: HY-150228
Purity: ≥95.0%
MitoCur-1, a curcumin analogue, is an inhibitor of mitochondrial antioxidative thioredoxin reductase 2 (TrxR2). MitoCur-1 has electrophilic and mitochondrial-targeting properties. MitoCur-1 induces reactive oxygen species (ROS) generation, exerts specifically antitumor efficacy .
1
1 Cited Publications
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L48H37 is an analog of Curcumin (HY-N0005) with improved chemical stability. L48H37 is a potent and specific myeloid differentiation protein 2 (MD2) inhibitor and inhibits the interaction and signaling transduction of LPS-TLR4/MD2. L48H37 is used for the research of sepsis or lung injury treatment .
1
1 Cited Publications
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Anti-inflammatory agent 35 (compound 5a27) is an orally active curcumin analogue with anti-inflammatory activity. Anti-inflammatory agent 35 blocks mitogen-activated protein kinase (MAPK) signaling and p65 nuclear translocation of NF-kB. Anti-inflammatory agent 35 also inhibits yellow neutrophil infiltration and pro-inflammatory cytokine production. Anti-inflammatory agent 35 significantly attenuates lipopolysaccharide (LPS)-induced acute lung injury (ALI) in vivo .
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Curcumin-β-D-glucuronide is a major metabolite after oral intake of Curcumin in hepatic tissue and portal blood. Curcumin-β-D-glucuronide can be used for the research of colon cancer .
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Pseudostellaria heterophylla (Miq.) Pax Metabolic Disease Plants Endogenous metabolite Human Gut Microbiota Metabolites Caryophyllaceae Extract Microorganisms Monophenols Ketones, Aldehydes, Acids Phenols Disease Research Fields
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Cat. No.: HY-N1967
CAS No.: 76474-56-1
Category:
Zingiber officinale Roscoe Zingiberaceae Extract Metabolic Disease Phenols Polyphenols Plants Disease Research Fields
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Soya Lecithin is a phospholipid mixture that can be used as a drug delivery vehicle and is a pharmaceutical excipient. Soya Lecithin can form a lipid bilayer structure through self-assembly, and its binding properties are amphiphilic (hydrophilic head and hydrophobic tail), encapsulating hydrophobic drugs. Soya Lecithin forms stable nanoliposomes or microemulsions, improves the solubility and cellular uptake efficiency of poorly soluble drugs (such as Curcumin (HY-N0005)), and exerts activities such as enhancing drug delivery and regulating cell proliferation .
Cat. No.: HY-N0007A
CAS No.: 24939-16-0
Synonyms: curcumin III; Didemethoxycurcumin
Cat. No.: HY-W009731
CAS No.: 120-46-7
Category:
Ketones, Aldehydes, Acids Metabolic Disease Leguminosae Extract Plants Disease Research Fields Glycyrrhiza uralensis Fisch.
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Cat. No.: HY-N0929
CAS No.: 36062-05-2
Category:
Zingiberaceae Extract Phenols Polyphenols Plants Curcuma longa Disease Research Fields Cancer
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Synonyms: CUR5-8
Research Areas:
Curcumin 5-8 (CUR5-8) is a potent and orally active naturally active curcumin (CUR) analog. Curcumin 5-8 inhibits lipid droplet formation. Curcumin 5-8 increases autophagy and inhibits Apoptosis. Curcumin 5-8 improves insulin resistance and insulin sensitivity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
