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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
359 Results for "
developmental modifier
" in MedChemExpress (MCE) Product Catalog:
Products (359)
359 Results for "developmental modifier" in MCE Product Catalog:
62
Target:
Research Areas:
Imiquimod (R 837), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and COVID-19 .
62
Target:
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Imiquimod hydrochloride (R 837 hydrochloride), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod hydrochloride exhibits antiviral and antitumor effects in vivo. Imiquimod hydrochloride can be used for the research of external genital, perianal warts, cancer and COVID-19 .
62
62 Publications Verification
Cat. No.: HY-B0180B
CAS No.: 896106-16-4
Target:
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Imiquimod maleate (R 837 maleate), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod maleate exhibits antiviral and antitumor effects in vivo. Imiquimod maleate can be used for the research of external genital, perianal warts, cancer and COVID-19 .
17
9
9 Cited Publications
Synonyms: RG7916; RO7034067
Target:
Research Areas:
Risdiplam (RG7916) is an orally administered, centrally and peripherally distributed SMN2 pre-mRNA splicing modifier that increases survival motor neuron (SMN) protein levels .
6
6 Cited Publications
Synonyms: 17α-Hydroxyprogesterone hexanoate; 17α-Hydroxyprogesterone caproate
Target:
Research Areas:
Hydroxyprogesterone caproate (17α-Hydroxyprogesterone hexanoate; 17α-Hydroxyprogesterone caproate) is a progesterone receptor (progesterone receptor) ligand and steroid hormone transcription inhibitor. Hydroxyprogesterone caproate downregulates estrogen receptors in target tissues and activates their metabolic pathways, and exhibits equivalent affinity for progesterone receptor A and progesterone receptor B. Hydroxyprogesterone caproate shows no consistent teratogenicity or developmental toxicity in rat, mouse and monkey models, but induces resorption or abortion in rhesus monkeys at human-equivalent doses. Hydroxyprogesterone caproate promotes the production of TNF-α in lipopolysaccharide-stimulated whole blood from non-pregnant women. Hydroxyprogesterone caproate can be used in scientific research related to preterm birth .
5
Target:
Research Areas:
RG7800 is a SMN2 splicing modifier. RG7800 has the potential for spinal muscular atrophy treatment.
5
Target:
5
Research Areas:
Aurintricarboxylic acid is a nanomolar-potency, allosteric antagonist with selectivity towards αβ-methylene-ATP-sensitive P2X1Rs and P2X3Rs, with IC50s of 8.6 nM and 72.9 nM for rP2X1R and rP2X3R, respectively . Aurintricarboxylic acid is a potent anti-influenza agent by directly inhibiting the neuraminidase . Aurintricarboxylic acid is an inhibitor of topoisomerase II and apoptosis . Aurintricarboxylic acid is a selective inhibitor of the TWEAK-Fn14 signaling pathway . Aurintricarboxylic acid also acts as a cystathionine-lyase (CSE) inhibitor with an IC50 of 0.6 μM . Aurintricarboxylic acid is a modifier of miRNAs that regulate miRNA function, with an IC50 of 0.47 µM .
5
5 Cited Publications
Synonyms: 20α-Hydroxycholesterol
Target:
4
4 Cited Publications
Synonyms: Tiabendazole; 2-(4-Thiazolyl)benzimidazole
Target:
Environmental Pollutants Mitochondrial Metabolism Parasite Caspase VEGFR MDM-2/p53 CDK Interleukin Related
Research Areas:
Infection Cardiovascular Disease Inflammation/Immunology Cancer
Thiabendazole is an orally available benzimidazole fungicide with repellent and anticancer activities. Thiabendazole can result in developmental malformations. Thiabendazole can be used for modeling .
4
4 Cited Publications
Synonyms: Porcn Inhibitor III
IWP L6 (Porcn Inhibitor III) is a Porcupine (Porcn) inhibitor with an EC50 of 0.5 nM. IWP L6 disrupts well-established Wnt-dependent developmental processes of embryonic and juvenile zebrafish .
4
4 Cited Publications
Cat. No.: HY-W011950
CAS No.: 52417-22-8
Target:
Research Areas:
Acridin-9-amine (9-Aminoacridine) hydrochloride hydrate is a mutagen and DNA modifier. Acridin-9-amine hydrochloride hydrate induces mutagenic lesions during DNA replication .
3
3 Cited Publications
Synonyms: GAP-134 Hydrochloride; ZP 1609 Hydrochloride
Target:
Research Areas:
Danegaptide Hydrochloride (GAP-134 Hydrochloride) is a potent, selective and orally active gap-junction modifier with an antiarrhythmic effect .
2
2 Cited Publications
Cat. No.: HY-B0847
CAS No.: 60207-90-1
Research Areas:
Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxicant and a hepatocarcinogen that has adverse reproductive and developmental toxicities in experimental animals .
2
2 Cited Publications
Cat. No.: HY-18593
CAS No.: 104723-60-6
Synonyms: 6-O-alpha-D-Maltosyl-beta-cyclodextrin
2
2 Cited Publications
Cat. No.: HY-B0831
CAS No.: 69327-76-0
Research Areas:
Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase .
2
2 Cited Publications
Cat. No.: HY-P80351
Synonyms: DAP1 antibody;
GAP modifying protein 1 antibody;
GMP 1 antibody;
OFC10 antibody;
PIC 1 antibody;
PIC1 antibody;
SENP2 antibody;
Sentrin 1 antibody;
Sentrin antibody;
Small ubiquitin related modifier 1 antibody;
Small ubiquitin-like modifier 1 antibody;
Small ubiquitin-related modifier 1 antibody;
SMT3 antibody;
SMT3 homolog 3 antibody;
SMT3 suppressor of mif two 3 homolog 1 antibody;
SMT3, yeast, homolog 3 antibody;
Smt3C antibody;
SMT3H3 antibody;
SUMO-1 antibody;
SUMO1 antibody;
SUMO1_HUMAN antibody;
Ubiquitin homology domain protein PIC1 antibody;
Ubiquitin Like 1 antibody;
Ubiquitin like protein SMT3C antibody;
Ubiquitin like protein UBL1 antibody;
Ubiquitin-homology domain protein PIC1 antibody;
Ubiquitin-like protein SMT3C antibody;
Ubiquitin-like protein UBL1 antibody;
UBL 1 antibody;
UBL1 antibody
2
2 Cited Publications
Target:
Research Areas:
Nitrocefin is a highly activated, chromogenic cephalosporin derivative. Nitrocefin is a chromogenic β-lactamase substrate. Nitrocefin undergoes a distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics .
2
2 Cited Publications
Cat. No.: HY-B1024
CAS No.: 16485-10-2
Synonyms: DL-Pantothenol; DL-Pantothenyl alcohol
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
