267 Results for "

enzyme–substrate

" in MedChemExpress (MCE) Product Catalog:
Products (267)

267 Results for "enzyme–substrate" in MCE Product Catalog:

53
53 Publications Verification
Cat. No.: HY-B0445A
CAS No.: 20111-18-6
Synonyms: β-DPN sodium; β-NAD sodium; β-Nicotinamide Adenine Dinucleotide sodium
NAD sodium is an orally effective cofactor and homeostatic regulator. NAD sodium can be reduced to β-nicotinamide adenine dinucleotide (NADH) during coupling with reactions that oxidize organic substrates. NAD sodium can be converted to β-nicotinamide adenine dinucleotide (NADH) and passes to the inside of mitochondria, which indirectly generates ATP. NAD sodium can be used for the research of non-alcoholic fatty liver disease, obesity, and glucose intolerance .
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22
22 Cited Publications
Cat. No.: HY-W011012
CAS No.: 4578-31-8
Adenosine 5'-monophosphate disodium is an orally active purine nucleotide, and participates in ATP metabolism. Adenosine 5'-monophosphate disodium is also a ligand for adenosine 2B receptor. Adenosine 5'-monophosphate disodium can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. Adenosine 5'-monophosphate disodium can be used for research of diabetes .
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14
14 Cited Publications
Cat. No.: HY-D0714
CAS No.: 298-96-4
Synonyms: 2,3,5-Triphenyltetrazolium chloride; TPTZ; TTC
Tetrazolium Red (2,3,5-Triphenyltetrazolium chloride; TTC) is a not brain-penetrant, colorless, water-soluble dye that is reduced by mitochondrial enzymes to a deep red, water-insoluble compound (formazan) mainly in the mitochondria of living cells. Tetrazolium Red is used to observe the activity of dehydrogenase, and it turns colorless to red when exposed to hydrogen. Tetrazolium Red distinguishes between surviving and infarcted brain tissue after stroke. Tetrazolium Red has been used to stain heart tissue to measure the extent of acute lesions and also used to stain brain tissue to detect the size of the infarcted area. The absorption wavelength of Tetrazolium Red is 570 nm .
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12
12 Cited Publications
Cat. No.: HY-D0719
CAS No.: 596-09-8
Synonyms: 3,6-Diacetoxyfluoran; Di-O-acetylfluorescein
Fluorescein diacetate is a cell permeable esterase-substrate. Fluorescein diacetate can be used as a fluorogenic substrate for hGSTP1-1.
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9
9 Cited Publications
Cat. No.: HY-N0187A
CAS No.: 5980-33-6
Synonyms: Hymecromone sodium salt; 4-MU sodium salt
Research Areas:  

Cancer

4-Methylumbelliferone (sodium salt) is a coumarin derivative. 4-Methylumbelliferone (sodium salt) can be used as a standard to quantify the free 4-methylumbelliferone released as a result of enzyme-substrate action. 4-Methylumbelliferone (sodium salt) inhibits hyaluronan production in vitro. 4-Methylumbelliferone (sodium salt) can be studied in ovarian cancer research .
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8
8 Cited Publications
Cat. No.: HY-15930B
CAS No.: 207738-08-7
Synonyms: Sure Blue TMB dihydrochloride x.hydrate
TMB (dihydrochloride x.hydrate) is the dihydrochloride x hydrate form of TMB (HY-15930). TMB (dihydrochloride x.hydrate) is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB (dihydrochloride x.hydrate) can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB (dihydrochloride x.hydrate) can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .
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7
7 Cited Publications
Cat. No.: HY-15926
CAS No.: 369-07-3
Synonyms: 2-Nitrophenyl β-D-galactopyranoside
ONPG is a colorimetric and spectrophotometric substrate for detection of β-galactosidase activity.
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6
6 Cited Publications
Cat. No.: HY-128851B
CAS No.: 55672-92-9
Purity:  99.46%
Coenzyme A (CoASH) sodium is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .
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6
6 Cited Publications
Cat. No.: HY-128851A
CAS No.: 18439-24-2
Purity:  95.40%
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .
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6
6 Cited Publications
Cat. No.: HY-18743
CAS No.: 55779-48-1
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. Renilla luciferase and substrate coelenterazine has been used as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. Coelenterazine is a superoxide anion-sensitive chemiluminescent probe and it can also be used in chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm) .
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6
6 Cited Publications
Cat. No.: HY-18743A
Research Areas:  

Cancer

Coelenterazine TFA is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. Renilla luciferase and substrate Coelenterazine TFA has been used as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. Coelenterazine TFA is a superoxide anion-sensitive chemiluminescent probe and it can also be used in chemiluminescent detection of peroxynitrite (Ex/Em = 429/466 nm) .
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4
4 Cited Publications
Cat. No.: HY-W017386
CAS No.: 3715-31-9
3-Methyl-2-oxovaleric acid sodium is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid sodium is a biomarker of mustard airway diseases (MADs) and uric acid stone .
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3
3 Cited Publications
Cat. No.: HY-116285
CAS No.: 29836-26-8
Purity:  99.92%
n-Octyl-β-d-glucopyranoside is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins. n-Octyl-β-d-glucopyranoside can completely inhibit cavitation-induced cell lysis in vitro .
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3
3 Cited Publications
Cat. No.: HY-D0183
CAS No.: 1800401-93-7
ATP-polyamine-biotin, the first cell-permeable ATP analogue, is an efficient kinase cosubstrate. ATP-polyamine-biotin promotes biotin labeling of kinase substrates in live cells .
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2
2 Cited Publications
Cat. No.: HY-126388
CAS No.: 9035-81-8
Trypsin Inhibitor, soybean is a potent and reversible inhibitor of trypsin .
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2
2 Cited Publications
Cat. No.: HY-116022A
CAS No.: 333338-18-4
Purity:  99.80%
Synonyms: p-Nitrophenyl phosphate disodium hexahydrate
4-Nitrophenyl phosphate (p-nitrophenyl phosphate) disodium hexahydrate is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases. 4-Nitrophenyl phosphate disodium hexahydrate is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by absorbance at 405 nm .
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2
2 Cited Publications
Cat. No.: HY-W011704
CAS No.: 10526-80-4
Synonyms: Phosphoenolpyruvate cyclohexylammoniu​m salt
Phosphoenolpyruvic acid (Phosphoenolpyruvate) cyclohexylammonium salt is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid cyclohexylammonium salt is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid cyclohexylammonium salt also exhibits cytoprotective and anti-oxidative properties .
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2
2 Cited Publications
Cat. No.: HY-W016412
CAS No.: 605-94-7
Synonyms: CoQ0
Coenzyme Q0 (CoQ0) is a potent, oral active ubiquinone compound can be derived from Antrodia cinnamomea. Coenzyme Q0 induces apoptosis and autophagy, suppresses of HER-2/AKT/mTOR signaling to potentiate the apoptosis and autophagy mechanisms. Coenzyme Q0 regulates NFκB/AP-1 activation and enhances Nrf2 stabilization in attenuation of inflammation and redox imbalance. Coenzyme Q0 has anti-angiogenic activity through downregulation of MMP-9/NF-κB and upregulation of HO-1 signaling .
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1
1 Cited Publications
Cat. No.: HY-15906
CAS No.: 122341-56-4
Purity:  99.93%
Synonyms: Lumi-Phos Plus; Lumigen PPD; PPD
AMPPD (Lumi-Phos Plus; Lumigen PPD) is a chemiluminescent substrate for alkaline phosphatase (APase). AMPPD is hydrolyzed by APase to generate an unstable dioxetane intermediate, and the intermediate releases a chemiluminescent signal when it decomposes. The luminescent signal of AMPPD can be detected by highly sensitive equipment, thereby achieving quantitative analysis of the target molecule. AMPPD can be used in ultrasensitive enzyme-linked immunosorbent assays (such as quantitative detection of human tissue kininogen), chemiluminescent detection of proteins and nucleic acids, and other fields .
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1
1 Cited Publications
Cat. No.: HY-15927
CAS No.: 2492-87-7
4-Nitrophenyl β-D-glucopyranoside is a chromogenic substrate for β-glucosidase. 4-Nitrophenyl β-D-glucopyranoside is converted to a colored product, p-nitrophenol that is easily detected spectrophotometrically at 405 nm when used in a β-glycosidase assay. 4-Nitrophenyl β-D-glucopyranoside is hydrolysed through intramolecular nucleophilic catalysis by the phosphate group in the 2-position. 4-Nitrophenyl β-D-glucopyranoside is promising for research of postmenopausal osteoporosis .
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