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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
73 Results for "
intermediate type
" in MedChemExpress (MCE) Product Catalog:
Products (73)
73 Results for "intermediate type" in MCE Product Catalog:
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1 Cited Publications
Cat. No.: HY-W011474
CAS No.: 24034-73-9
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1 Cited Publications
Synonyms: α-Hydroxybutyric acid
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields Cardiovascular System Disorder
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1 Cited Publications
Synonyms: (-)-Lauroylcarnitine
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Immune System Disorder Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields
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1 Cited Publications
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Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields
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1 Cited Publications
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Vimentin-IN-1 is a FiVe1 derivative, an orally active and selective anticancer agent. FiVe1 binds type III intermediate filament protein vimentin (VIM), to induce hyperphosphorylation of Ser56, resulting selective disruption of mitosis and multinucleation in transformed VIM-expressing mesenchymal cancer cells. Vimentin-IN-1 shows better oral bioavailability and pharmacokinetic profiles than FiVe1 .
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1 Cited Publications
Cat. No.: HY-W010040
CAS No.: 156-39-8
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Monophenols Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Phenols Nervous System Disorder Endogenous metabolite Disease Research Fields
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1 Cited Publications
Cat. No.: HY-W008820S
CAS No.: 154184-99-3
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Cat. No.: HY-W008820
CAS No.: 110-94-1
Category:
Microorganisms Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields
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4-Hydroxyindole is a type of hydroxyindole in which the 1H-indole at position 4 is substituted by a hydroxyl group.
4-Hydroxyindole serves as an important raw material or intermediate in the synthesis of pharmaceutical products and industrial polymers.
4-Hydroxyindole inhibits amyloid fibrillization and induces liver function impairment, thyroid abnormalities, and blood glucose fluctuations in mice.
4-Hydroxyindole holds potential for research in neurodegenerative diseases and metabolic disorders .
Cat. No.: HY-78004S
CAS No.: 94371-89-8
1,2-Diphenylethane-d14 is the d14-labeled Bibenzyl (HY-78004). Bibenzyl (s-Diphenylethane; Dibenzyl) is the parent core structure of bibenzyl-type natural products and an intermediate in organic synthesis. Hydroxyl-substituted derivatives of Bibenzyl are mainly isolated from plants such as Dendrobium (Orchidaceae) and Cannabaceae. These derivatives accumulate when plants are exposed to fungal infection and biotic stress, and exhibit antioxidant, anti-inflammatory, and anti-hepatic steatosis activities .
Cat. No.: HY-W002339
CAS No.: 1121-25-1
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Alkaloids Other Diseases Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Pyridine Alkaloids Leguminosae Extract Plants Other Families Extract Disease Research Fields
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Cat. No.: HY-Y0973
CAS No.: 56602-33-6
Cat. No.: HY-N0348
CAS No.: 24916-90-3
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Dexamethasone 9,11-epoxide is a type of glucocorticoid. Dexamethasone 9,11-epoxide can be used as a drug intermediate to prepare Dexamethasone (HY-14648) and Betamethasone (HY-13570). Dexamethasone 9,11-epoxide can be employed in the research of inflammation and immune diseases .
Cat. No.: HY-W587796
CAS No.: 2641-81-8
Synonyms: 6-PGδL; 6-Phosphonoglucono-D-lactone
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6-Phosphoglucono-δ-lactone (6-PGδL), a reversal substrate of glucose-6-phosphate dehydrogenase (G6PD), is an intermediate compound in the oxidative branch of the pentose phosphate pathway (PPP). 6-Phosphoglucono-δ-lactone produced from D-glucose-6-phosphate by glucose-6-phosphate dehydrogenase (G6PDH) and is converted to 6-phosphoglutonate by lactonase. 6-Phosphoglucono-δ-lactone can be used for heart failure, type 2 diabetes and cancers research .
Cat. No.: HY-CE02028
CAS No.: 167357-83-7
Synonyms: Glutaconyl-coenzyme A
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Glutaconyl-CoA (Glutaconyl-coenzyme A) is a key metabolic intermediate in the mitochondrial catabolic pathways of lysine, hydroxylysine and tryptophan. Glutaconyl-CoA competitively inhibits wild-type glutaryl-CoA dehydrogenase (GCDH) with a Ki value of 1.1 µM. Glutaconyl-CoA is generated via the oxidative decarboxylation of glutaryl-CoA catalyzed by GCDH, and is subsequently further metabolized. Glutaconyl-CoA can be used in the research of type I glutaric aciduria .
Cat. No.: HY-W130074
CAS No.: 1686-14-2
α-Pinene oxide is a type of monoterpene epoxidation intermediate. α-Pinene oxide is produced via the cytochrome P-450-mediated oxidation pathway in Dendroctonus terebrans body microsomes and rat liver microsomes, and can be further converted into alcohols, ketones and insect pheromone derivatives. α-Pinene oxide can generate the perfume intermediate myrtenal. α-Pinene oxide is used in studies related to terpenoid metabolism and perfume synthesis .
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Infection Alkaloids Plants Papaver somniferum Linn. Disease Research Fields Isoquinoline Alkaloids Papaveraceae Extract
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
