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Results for "

linolenic acid

" in MedChemExpress (MCE) Product Catalog:

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Inflammation/Immunology (15)

Metabolic Disease (21)

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Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0728

*α-Linolenic* acid** Maximum Cited Publications 11 Publications Verification ALA free base; C18:3 (9Z,12Z,15Z) free base; C18:3 n-3 free base	Environmental Pollutants Akt PI3K	Cardiovascular Disease Cancer
α-Linolenic acid (ALA (free base); C18:3 (9Z,12Z,15Z) (free base); C18:3 n-3 (free base)) is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .

HY-N7140

*Gamma-Linolenic* acid** 5+ Cited Publications γ-linolenic acid	Endogenous Metabolite Apoptosis NF-κB ERK JNK	Neurological Disease Inflammation/Immunology Cancer
Gamma-linolenic acid (γ-Linolenic acid) is an orally active unsaturated fatty acid. Gamma-linolenic acid exerts anti-inflammatory effects by inhibiting the NF-κB pathway and the phosphorylation of ERK1/2 and JNK. At the same time, it exerts anticancer effects by inducing apoptosis (Apoptosis) in cancer cells. Additionally, Gamma-linolenic acid also has antioxidant and memory-improving effects. It holds promise for research in the fields of inflammation, neurology, and cancer diseases .

HY-A0143

*Dihomo-γ-linolenic* acid** 4 Publications Verification DGLA; all-cis-8,11,14-Eicosatrienoic acid	Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Cancer
Dihomo-γ-linolenic acid (DGLA) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system .

HY-N0728S3

*α-Linolenic* acid-13C18**	Isotope-Labeled Compounds PI3K Akt	Cardiovascular Disease Cancer
α-Linolenic acid- ¹³C₁₈ is the ¹³C labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .

HY-21268

Methyl linolenate 1 Publications Verification linolenic acid methyl ester	Environmental Pollutants Melatonin Receptor	Metabolic Disease
Methyl linolenate is a polyunsaturated fattly acid (PUFA). Methyl linolenate has an anti-melanogenesis activity with an IC₅₀ of 60 μM. Methyl linolenate can also be used for studies of the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids .

HY-27787

α-Eleostearic acid cis-Eleostearic acid	Apoptosis Ferroptosis	Metabolic Disease Cancer
α-Eleostearic acid (cis-Eleostearic acid), a conjugated linolenic acid, is an apoptosis inducer. α-Eleostearic acid is also a ferroptosis inducer. α-Eleostearic acid exhibits antioxidant and antitumor activity .

HY-122464S2

(±)-Jasmonic acid-d5	Isotope-Labeled Compounds	Others
(±)-Jasmonic acid-d₅ is the deuterium labeled (±)-Jasmonic acid. (±)-Jasmonic acid is a plant growth regulator and a derivative of α-linolenic acid. (±)-Jasmonic acid decreases chlorophyll levels in green and etiolated barley leaf segments and inhibits elongation of rice seedlings.

HY-139066

Punicic acid 1 Publications Verification Trichosanic acid	TNF Receptor GLUT Proteasome Tau Protein PKC	Neurological Disease Metabolic Disease Inflammation/Immunology
Punicic acid is a bioactive compound of pomegranate seed oil. Punicic acid is an isomer of conjugated α-linolenic acid and ω-5 polyunsaturated fatty acids. Punicic acid has anti-inflammatory and antioxidant activities and can inhibit the expression of inflammatory mediators such as tumor necrosis factor α (TNF-α). Punicic acid can also reduce the formation of β-amyloid deposits and hyperphosphorylation of tau by increasing the expression of GLUT4 protein and inhibiting the overactivation of calpain, and is used to prevent and treat neurodegenerative diseases. In addition, punicic acid also has breast cancer inhibitor properties that depend on lipid peroxidation and PKC pathways .

HY-W009276

*γ-Linolenic* Acid methyl ester** Methyl GLA	Apoptosis	Cancer
γ-Linolenic Acid methyl ester (Methyl GLA) is an esterified version of γ-Linolenic Acid (GLA), which is an ω-6 fatty acid, serves as melanoma cell proliferation inhibitors. γ-Linolenic Acid methyl ester inhibits ADP-induced blood platelet aggregation and induces apoptosis .

HY-N0728S

*α-Linolenic* acid-d5**	Isotope-Labeled Compounds PI3K Akt	Cardiovascular Disease Cancer
α-Linolenic acid-d₅ is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .

HY-108396

*γ-Linolenic* acid ethyl ester** Ethyl γ-linolenate	Leukotriene Receptor	Inflammation/Immunology
γ-Linolenic acid ethyl ester (Ethyl γ-linolenate) is a leukotriene B₄ receptor 4 (LTB₄) antagonist .

HY-122464A

Jasmonic acid (-)-Jasmonic acid	Drug Derivative	Others
Jasmonic acid ((-)-Jasmonic acid) is a plant growth regulator and a derivative of Linolenic acid (HY-N0728). Jasmonic acid enhances plant resistance and is widely used as a stress protectant. Jasmonic acid is an endogenous plant hormone and a plant growth inhibitor .

HY-N0728R

*α-Linolenic* acid (Standard)** Maximum Cited Publications 11 Publications Verification	Reference Standards PI3K Akt	Cardiovascular Disease Cancer
α-Linolenic acid (Standard) is the analytical standard of α-Linolenic acid. This product is intended for research and analytical applications. α-Linolenic acid, isolated from Perilla frutescens, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .

HY-A0143A

*Dihomo-γ-linolenic* acid sodium** 4 Publications Verification DGLA sodium; all-cis-8,11,14-Eicosatrienoic acid sodium	Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Cancer
Dihomo-γ-linolenic acid (DGLA; all-cis-8,11,14-Eicosatrienoic acid) sodium is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid (sodium) attenuates atherosclerosis in the apolipoprotein E deficient mouse model system .

HY-W004283R

Pentadecanoic acid (Standard)	Reference Standards Endogenous Metabolite JAK STAT PPAR p38 MAPK JNK ERK Caspase Apoptosis	Metabolic Disease Cancer
α-Linolenic acid (Standard) is the analytical standard of α-Linolenic acid. This product is intended for research and analytical applications. α-Linolenic acid, isolated from Perilla frutescens, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .

HY-130323

13-HPOT	Bacterial	Infection
13-HPOT is a linolenic acid hydroperoxide and an antibacterial agent. 13-HPOT interacts with lipid representatives of bacterial inner membranes. 13-HPOT exerts dose-dependent in vitro antibacterial activity against Pectobacterium carotovorum, Pseudomonas syringae pv. syringae DC3000, and Xanthomonas translucens pv. translucens .

HY-N7140R

*Gamma-Linolenic* acid (Standard)** 5+ Cited Publications γ-linolenic acid (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Gamma-Linolenic acid (Standard) is the analytical standard of Gamma-Linolenic acid. This product is intended for research and analytical applications. Gamma-linolenic acid (γ-Linolenic acid) is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from Perilla frutescens. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease .

HY-A0143S

*Dihomo-γ-linolenic* acid-d6** DGLA-d₆; all-cis-8,11,14-Eicosatrienoic acid-d₆	Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Cancer
Dihomo-γ-linolenic acid-d₆ (DGLA-d₆) is the deuterium labeled Dihomo-γ-linolenic acid. Dihomo-γ-linolenic acid (all-cis-8,11,14-Eicosatrienoic acid) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system .

HY-N0728A

*α-Linolenic* acid sodium** Maximum Cited Publications 11 Publications Verification ALA; C18:3 (9Z,12Z,15Z); C18:3 n-3	Environmental Pollutants Akt PI3K	Cardiovascular Disease Cancer
α-Linolenic acid sodium (ALA; C18:3 (9Z,12Z,15Z); C18:3 n-3) is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid sodium can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid sodium possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .

HY-113448

CE(20:3(8Z,11Z,14Z)) 20:3 (8Z,11Z,14Z) CE; 20:3 n-6 CE; 20:3 (8Z,11Z,14Z) Cholesterol Ester	Endogenous Metabolite	Cardiovascular Disease
Cholesteryl homo-γ-linolenate is a cholesterol ester. It accumulates in the adrenal gland of rabbits fed a diet high in linolenic acid.1 Levels of cholesteryl homo-γ-linolenate are decreased and positively correlate with cognitive decline in HIV-infected humans.

HY-122464S1

Jasmonic acid-d5	Isotope-Labeled Compounds	Others
Jasmonic acid-d₅ is deuterium labeled (±)-Jasmonic acid. (±)-Jasmonic acid is a plant growth regulator and a derivative of α-linolenic acid. (±)-Jasmonic acid decreases chlorophyll levels in green and etiolated barley leaf segments and inhibits elongation of rice seedlings.

HY-116015

*Dihomo-γ-Linolenic* acid methyl ester**	Endogenous Metabolite	Inflammation/Immunology
Dihomo-γ-Linolenic acid methyl ester is the methyl ester form of Dihomo-γ-Linolenic Acid (DGLA) (HY-A0143). Dihomo-γ-Linolenic acid is an n-6 polyunsaturated fatty acid that is metabolized mainly through the cyclooxygenase (COX) pathway to the anti-inflammatory eicosanoid prostaglandin (PG) E1. Dihomo-γ-Linolenic acid has anti-inflammatory and antiproliferation effects .

HY-113776

15(S)-HETRE	Lipoxygenase	Inflammation/Immunology
15(S)-HETRE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid. It is an inhibitor of 5-LO in human PMNL with an IC₅₀ value of 4.6 μM. In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE.

HY-115707

1-Palmitoyl-3-Linolenoyl-rac-glycerol 16:0/0:0/18:3-DG; DG(16:0/0:0/18:3); 1-Palmitin-3-Linolenin	Others	Others
1-Palmitoyl-3-Linolenoyl-rac-glycerol (16:0/0:0/18:3-DG) is a diacylglycerol containing palmitic acid (HY-N0830) and α-linolenic acid (HY-N0728) at the sn-1 and sn-3 positions, respectively. It has been found in the peel and pulp of unripe Dwarf Cavendish bananas.

HY-138148

13(S)-HPOTrE(γ)	Lipoxygenase	Inflammation/Immunology
13(S)-HpOTrE(γ) is a monohydroxy PUFA produced by the action of soybean lipoxygenase-1 (LO-1) on γ-linolenic acid. Further action of soybean LO-1 converts 13(S)-HpOTrE(γ) to all four isomers of 6,13-DiHOTrE.2 At concentrations greater than 100 μM, 13(S)-HpOTrE(γ) inhibits the activity of soybean LO-1.

HY-W317836

(Rac)-Jasmonic acid	Biochemical Assay Reagents	Others
(Rac)-Jasmonic acid is the racemate of Jasmonic acid (HY-122464A). Jasmonic acid ((-)-Jasmonic acid) is a plant growth regulator and a derivative of Linolenic acid (HY-N0728) .

HY-32088

Ethyl 10-bromodecanoate	Bacterial	Infection Inflammation/Immunology
Ethyl 10-bromodecanoate is an antiinflammatory and hemostatic agent. Ethyl 10-bromodecanoate is a member of the family of linolenic acid, which includes diethyl succinate and ethyl palmitate. Ethyl 10-bromodecanoate has been shown to have antibacterial properties.

HY-171837

c9,t11,c15-CLNA	Caspase	Cancer
c9,t11,c15-CLNA is a conjugated linolenic acid (CLNA) isomer produced by Lactobacillus plantarum ZS2058. c9,t11,c15-CLNA has significant anti-proliferation activity against colon cancer cells (IC₅₀: 18.26 μM). c9,t11,c15-CLNA induces pyroptosis by activating the canonical pyroptosis pathway mediated by caspase-1. c9,t11,c15-CLNA can be used in the study of colon cancer .

HY-N0728S2

*α-Linolenic* acid-d14**	Isotope-Labeled Compounds PI3K Akt	Cardiovascular Disease Cancer
α-Linolenic acid-d₁₄ is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .

HY-W009276R

*γ-Linolenic* Acid methyl ester (Standard)** Methyl GLA (Standard)	Reference Standards Apoptosis	Cancer
γ-Linolenic Acid methyl ester (Standard) is the analytical standard of γ-Linolenic Acid methyl ester. This product is intended for research and analytical applications. γ-Linolenic Acid methyl ester (Methyl GLA) is an esterified version of γ-Linolenic Acid (GLA), which is an ω-6 fatty acid, serves as melanoma cell proliferation inhibitors. γ-Linolenic Acid methyl ester inhibits ADP-induced blood platelet aggregation and induces apoptosis .

HY-W587910

Linolenic acid glycidyl ester 9,12,15-Octadecatrienoic acid; Glycidyl linolenate	Biochemical Assay Reagents	Metabolic Disease
Linolenic acid glycidyl ester (9,12,15-Octadecatrienoic acid; Glycidyl linolenate) is an ester product.

HY-W744842

*γ-Linolenic* acid ethyl ester-d5** Ethyl γ-linolenate-d₅	Isotope-Labeled Compounds Leukotriene Receptor	Inflammation/Immunology
γ-Linolenic acid ethyl ester-d₅ (Ethyl γ-linolenate-d₅) is the deuterium labeled γ-Linolenic acid ethyl ester (HY-108396). γ-Linolenic acid ethyl ester (Ethyl γ-linolenate) is a leukotriene B4 receptor 4 (LTB4) antagonist .

HY-W740965

Linolenic acid glycidyl ester-d5 9,12,15-Octadecatrienoic acid-d₅; Glycidyl linolenate-d₅	Isotope-Labeled Compounds Biochemical Assay Reagents	Metabolic Disease
Linolenic acid glycidyl ester-d₅ (9,12,15-Octadecatrienoic acid-d₅; Glycidyl linolenate-d₅) is the deuterium labeled Linolenic acid glycidyl ester (HY-W587910). Linolenic acid glycidyl ester (9,12,15-Octadecatrienoic acid; Glycidyl linolenate) is an ester product.

HY-165026

1,2,3-tri-γ-Linolenoyl glycerol γ-linolenic acid triglyceride; γ-Linolenin	Endogenous Metabolite	Others
1,2,3-tri-γ-Linolenoyl glycerol is a triacylglycerol with γ-linolenic acid attached to the three esterification sites (1, 2 and 3) of glycerol .

HY-158547

Etherolenic acid	Drug Metabolite	Others
Etherolenic acid, a divinyl ether oxylipin, is a metabolite of Linolenic acid .

HY-169768

(E/Z)-Etherolenic acid	Drug Metabolite	Metabolic Disease
(E/Z)-Etherolenic acid is a divinyl ether oxylipin and is a metabolite of Linolenic acid .

HY-172579

(±)15,16-DiHODE	Drug Derivative	Metabolic Disease
(±)15,16-DiHODE is a derived oxylipin of α-Linolenic acid (HY-N0728) .

HY-165017

Etheroleic acid	Fungal	Infection
Etheroleic acid has antifungal activity against the powdery mildew B. graminis on the second leaves of barley seedlings. Etheroleic acid is a metabolite of Linolenic acid .

HY-145521

5(S)-HETrE 5(S)-Hydroxy-6E,8Z,11Z-eicosatrienoic acid	Endogenous Metabolite	Cardiovascular Disease
5(S)-HETrE is a metabolite of the ω-6 fatty acid γ-linolenic acid. 5(S)-HETrE can be elevated in serum levels in an obesity mouse model .

HY-122464B

7-epi Jasmonic acid 2-iso Jasmonic acid; 7-iso Jasmonic acid	Herbicide	Others
7-epi Jasmonic acid is the isomer of (±)-Jasmonic acid (HY-122464). (±)-Jasmonic acid is a plant growth regulator and a derivative of α-linolenic acid. (±)-Jasmonic acid decreases chlorophyll levels in green and etiolated barley leaf segments and inhibits elongation of rice seedlings.

HY-21268S

Methyl linolenate-13C18 linolenic acid methyl ester-¹³C₁₈	Isotope-Labeled Compounds	Others
Methyl linolenate- ¹³C₁₈ is the ¹³C labeled Methyl linolenate . Methyl linolenate is a polyunsaturated fattly acid (PUFA). It is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids . The IC₅₀ is 60 uM .

HY-170458

18:0-18:2 PG sodium 1-Stearoyl-2-linoleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium	Biochemical Assay Reagents	Others
18:0-18:2 PG (1-Stearoyl-2-linoleoyl-sn-glycero-3-phospho-(1'-rac-glycerol)) sodium is a glycerophospholipid contains Stearic acid (HY-B2219), Linolenic acid (HY-N0728) and phospho-rac-(1-glycerol) .

HY-W778471

rac-1-Linoleoyl-3-linolenoyl-propanetriol DG(18:2/0:0/18:3); 1-Linolein-3-α-Linolenin; 1-Linolein-3-Linolenin	Endogenous Metabolite	Metabolic Disease
1-Linoleoyl-3-α-linolenoyl-rac-glycerol is a diacylglycerol that contains linoleic acid (HY-N0729) at the sn-1 position and α-linolenic acid (HY-N0728) at the sn-3 position. It has been found in olive oil subjected to lipase-catalyzed glycerolysis with immobilized lipase B from C. antarctica.

HY-121619

Jacaric acid	Apoptosis	Inflammation/Immunology Cancer
Jacaric acid is a conjugated linolenic acid, which inhibits viability in cells PC-3 (IC₅₀ is 11.8 μM), LNCaP (IC₅₀ is 2.2 μM) and DLD-1, induces apoptosis and necrosis . Jacaric acid exhibits anticaner activity against prostate cancer and adenocarcinoma . Jacaric acid exhibits immunomodulating activity in murine peritoneal macrophages as an immunopotentiator . Jacaric acid is orally active.

HY-131310

9(S)-HpOTrE	Endogenous Metabolite	Metabolic Disease
9(S)-HpOTrE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase (5-LO) on α-linolenic acid. It can be further metabolized to colnelenic acid by a divinyl ether synthase activity found in garlic and potato microsomal fractions. 9(S)-HpOTrE also serves as a substrate for further oxidation by both soybean and potato LOs, resulting in the formation of 9,16-dihydroperoxy acid.The suicide inactivation of LOs when 9(S)-HpOTrE is used as a substrate is thought to occur via formation of an unstable epoxide.

HY-171837A

t9,t11,c15-CLNA	TNF Receptor Interleukin Related SOD	Inflammation/Immunology
t9,t11,c15-CLNA is a conjugated linolenic acid (CLNA) isomer produced by Lactobacillus plantarum ZS2058. t9,t11,c15-CLNA has the main activities of anti-inflammatory, antioxidant and improving intestinal barrier function. The regulatory mechanism of t9,t11,c15-CLNA includes upregulation of tight junction proteins, inhibition of pro-inflammatory cytokines (such as TNF-α, IL-6) and activation of antioxidant enzymes (such as SOD, CAT). t9,t11,c15-CLNA can be used in the study of inflammatory bowel diseases (such as colitis) .

HY-185226

*γ-Linolenic* acid NHS ester**	Drug Metabolite	Cancer
γ-Linolenic acid NHS ester is a lipid metabolite of γ-Linolenic acid (GLA) (HY-N7140), which can serve as a synthetic intermediate or probe labeling reagent for the preparation of GLA conjugates. In practical applications, γ-Linolenic acid NHS ester can be conjugated with taxanes and polysaccharides to form dual-type conjugates for drug delivery purposes .

HY-180676

*(R)-2-Hydroperoxy-α-linolenic* acid**	Nucleoside Antimetabolite/Analog	Metabolic Disease
(R)-2-Hydroperoxy-α-linolenic acid is a nucleoside metabolite.

HY-180675

*(R)-2-Hydroxy-α-linolenic* acid**	Nucleoside Antimetabolite/Analog	Metabolic Disease
(R)-2-Hydroxy-α-linolenic acid is a nucleoside metabolite.

HY-108396R

*γ-Linolenic* acid ethyl ester (Standard)** Ethyl γ-linolenate (Standard)	Reference Standards Leukotriene Receptor	Inflammation/Immunology
γ-Linolenic acid ethyl ester (Standard) is the analytical standard of γ-Linolenic acid ethyl ester (HY-108396). This product is intended for research and analytical applications. γ-Linolenic acid ethyl ester (Ethyl γ-linolenate) is a leukotriene B4 receptor 4 (LTB4) antagonist .

Cat. No.	Product Name	Type

HY-W317836

(Rac)-Jasmonic acid	Biochemical Assay Reagents
(Rac)-Jasmonic acid is the racemate of Jasmonic acid (HY-122464A). Jasmonic acid ((-)-Jasmonic acid) is a plant growth regulator and a derivative of Linolenic acid (HY-N0728) .

HY-170458

18:0-18:2 PG sodium 1-Stearoyl-2-linoleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium	Biochemical Assay Reagents
18:0-18:2 PG (1-Stearoyl-2-linoleoyl-sn-glycero-3-phospho-(1'-rac-glycerol)) sodium is a glycerophospholipid contains Stearic acid (HY-B2219), Linolenic acid (HY-N0728) and phospho-rac-(1-glycerol) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0728

*α-Linolenic* acid** Maximum Cited Publications 11 Publications Verification ALA free base; C18:3 (9Z,12Z,15Z) free base; C18:3 n-3 free base	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Labiatae Ulex europaeus L. Disease markers Plants Endogenous metabolite Disease Research Fields Cardiovascular System Disorder Source Classification	Environmental Pollutants Akt PI3K
α-Linolenic acid (ALA (free base); C18:3 (9Z,12Z,15Z) (free base); C18:3 n-3 (free base)) is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .

HY-N7140

*Gamma-Linolenic* acid** 5+ Cited Publications γ-linolenic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Labiatae Disease markers Endocrine diseases Metabolic Disease Tadehagi triquetrum (L.) Ohashi Plants Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Apoptosis NF-κB ERK JNK
Gamma-linolenic acid (γ-Linolenic acid) is an orally active unsaturated fatty acid. Gamma-linolenic acid exerts anti-inflammatory effects by inhibiting the NF-κB pathway and the phosphorylation of ERK1/2 and JNK. At the same time, it exerts anticancer effects by inducing apoptosis (Apoptosis) in cancer cells. Additionally, Gamma-linolenic acid also has antioxidant and memory-improving effects. It holds promise for research in the fields of inflammation, neurology, and cancer diseases .

HY-A0143

*Dihomo-γ-linolenic* acid** 4 Publications Verification DGLA; all-cis-8,11,14-Eicosatrienoic acid	Cardiovascular Disease Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Endocrine diseases Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite
Dihomo-γ-linolenic acid (DGLA) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system .

HY-21268

Methyl linolenate 1 Publications Verification linolenic acid methyl ester	Structural Classification other families Classification of Application Fields Other Diseases Plants Disease Research Fields Lipid Source Classification	Environmental Pollutants Melatonin Receptor
Methyl linolenate is a polyunsaturated fattly acid (PUFA). Methyl linolenate has an anti-melanogenesis activity with an IC₅₀ of 60 μM. Methyl linolenate can also be used for studies of the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids .

HY-139066

Punicic acid 1 Publications Verification Trichosanic acid	Structural Classification Punica granatum L. Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Punicaceae Plants Disease Research Fields Source Classification	TNF Receptor GLUT Proteasome Tau Protein PKC
Punicic acid is a bioactive compound of pomegranate seed oil. Punicic acid is an isomer of conjugated α-linolenic acid and ω-5 polyunsaturated fatty acids. Punicic acid has anti-inflammatory and antioxidant activities and can inhibit the expression of inflammatory mediators such as tumor necrosis factor α (TNF-α). Punicic acid can also reduce the formation of β-amyloid deposits and hyperphosphorylation of tau by increasing the expression of GLUT4 protein and inhibiting the overactivation of calpain, and is used to prevent and treat neurodegenerative diseases. In addition, punicic acid also has breast cancer inhibitor properties that depend on lipid peroxidation and PKC pathways .

HY-122464A

Jasmonic acid (-)-Jasmonic acid	Structural Classification Leguminosae Ketones, Aldehydes, Acids Plants Vicia faba L. Source Classification	Drug Derivative
Jasmonic acid ((-)-Jasmonic acid) is a plant growth regulator and a derivative of Linolenic acid (HY-N0728). Jasmonic acid enhances plant resistance and is widely used as a stress protectant. Jasmonic acid is an endogenous plant hormone and a plant growth inhibitor .

HY-N0728R

*α-Linolenic* acid (Standard)** Maximum Cited Publications 11 Publications Verification	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Ulex europaeus L. Plants Endogenous metabolite Microorganisms Labiatae Disease markers Disease Research Fields Cardiovascular System Disorder Source Classification	Reference Standards PI3K Akt
α-Linolenic acid (Standard) is the analytical standard of α-Linolenic acid. This product is intended for research and analytical applications. α-Linolenic acid, isolated from Perilla frutescens, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .

HY-A0143A

*Dihomo-γ-linolenic* acid sodium** 4 Publications Verification DGLA sodium; all-cis-8,11,14-Eicosatrienoic acid sodium	Microorganisms Ketones, Aldehydes, Acids Source Classification	Endogenous Metabolite
Dihomo-γ-linolenic acid (DGLA; all-cis-8,11,14-Eicosatrienoic acid) sodium is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid (sodium) attenuates atherosclerosis in the apolipoprotein E deficient mouse model system .

HY-W004283R

Pentadecanoic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite JAK STAT PPAR p38 MAPK JNK ERK Caspase Apoptosis
α-Linolenic acid (Standard) is the analytical standard of α-Linolenic acid. This product is intended for research and analytical applications. α-Linolenic acid, isolated from Perilla frutescens, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .

HY-N7140R

*Gamma-Linolenic* acid (Standard)** 5+ Cited Publications γ-linolenic acid (Standard)	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Labiatae Disease markers Endocrine diseases Metabolic Disease Tadehagi triquetrum (L.) Ohashi Plants Endogenous metabolite Disease Research Fields Source Classification	Reference Standards Endogenous Metabolite
Gamma-Linolenic acid (Standard) is the analytical standard of Gamma-Linolenic acid. This product is intended for research and analytical applications. Gamma-linolenic acid (γ-Linolenic acid) is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from Perilla frutescens. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease .

HY-116015

*Dihomo-γ-Linolenic* acid methyl ester**	Structural Classification Natural Products Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite
Dihomo-γ-Linolenic acid methyl ester is the methyl ester form of Dihomo-γ-Linolenic Acid (DGLA) (HY-A0143). Dihomo-γ-Linolenic acid is an n-6 polyunsaturated fatty acid that is metabolized mainly through the cyclooxygenase (COX) pathway to the anti-inflammatory eicosanoid prostaglandin (PG) E1. Dihomo-γ-Linolenic acid has anti-inflammatory and antiproliferation effects .

HY-121619

Jacaric acid	Caprifoliaceae Ketones, Aldehydes, Acids Plants Centranthus ruber (L.) DC Source Classification	Apoptosis
Jacaric acid is a conjugated linolenic acid, which inhibits viability in cells PC-3 (IC₅₀ is 11.8 μM), LNCaP (IC₅₀ is 2.2 μM) and DLD-1, induces apoptosis and necrosis . Jacaric acid exhibits anticaner activity against prostate cancer and adenocarcinoma . Jacaric acid exhibits immunomodulating activity in murine peritoneal macrophages as an immunopotentiator . Jacaric acid is orally active.

HY-180676

*(R)-2-Hydroperoxy-α-linolenic* acid**	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Nucleoside Antimetabolite/Analog
(R)-2-Hydroperoxy-α-linolenic acid is a nucleoside metabolite.

HY-180675

*(R)-2-Hydroxy-α-linolenic* acid**	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Nucleoside Antimetabolite/Analog
(R)-2-Hydroxy-α-linolenic acid is a nucleoside metabolite.

HY-N17464

Methyl (9Z,12Z,14E)-16-hydroxy-9,12,14-octadecatrienoate	Structural Classification Solanum tuberosum L. Solanaceae Plants Lipid Source Classification	Drug Derivative
Methyl (9Z,12Z,14E)-16-hydroxy-9,12,14-octadecatrienoate is an esterified oxylipin and esterified hydroxy linolenic acid (HOT-Me) that can be found in potato tubers (Solanum tuberosum L. cv. Bintje) .

HY-N19627

3'-O-Methyl-(-)-epicatechin gallate 3′-M-ECG	Structural Classification Flavonoids Camellia sinensis (L.) O. Ktze. Plants Other Flavonoids Source Classification Theaceae	Drug Derivative
3'-O-Methyl-(-)-epicatechin gallate (3′-M-ECG) is a methylated Catechin (HY-N0898) derivative and is an antioxidant agent. 3'-O-Methyl-(-)-epicatechin gallate reduces oxygen consumption and prevents decreases in linoleic and α-linolenic acids to protect canola oil from lipid oxidation when heated .

HY-N17745

(-)-EGCG-3'-O-Me	Brassica rapa var. oleifera de Candolle Structural Classification Phenols Polyphenols Plants Brassicaceae Source Classification
(-)-EGCG-3'-O-Me is a catechin derivative (HY-N0898). (-)-EGCG-3'-O-Me inhibits lipid oxidation in rapeseed oil by reducing oxygen consumption and protecting linoleic acid and α-linolenic acid from degradation during heating. The antioxidant activity of (-)-EGCG-3'-O-Me in heated rapeseed oil is lower than that of its non-methylated precursor, (-)-epigallocatechin (EGCG) (HY-N0225) .

Cat. No.	Product Name	Chemical Structure

HY-N0728S3

α-Linolenic acid-13C18

α-Linolenic acid- ¹³C₁₈ is the ¹³C labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .

HY-122464S2

(±)-Jasmonic acid-d5
(±)-Jasmonic acid-d₅ is the deuterium labeled (±)-Jasmonic acid. (±)-Jasmonic acid is a plant growth regulator and a derivative of α-linolenic acid. (±)-Jasmonic acid decreases chlorophyll levels in green and etiolated barley leaf segments and inhibits elongation of rice seedlings.

HY-N0728S

*α-Linolenic* acid-d5**
α-Linolenic acid-d₅ is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .

HY-A0143S

*Dihomo-γ-linolenic* acid-d6**
Dihomo-γ-linolenic acid-d₆ (DGLA-d₆) is the deuterium labeled Dihomo-γ-linolenic acid. Dihomo-γ-linolenic acid (all-cis-8,11,14-Eicosatrienoic acid) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system .

HY-N0728S2

α-Linolenic acid-d14

α-Linolenic acid-d₁₄ is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .

HY-W744842

*γ-Linolenic* acid ethyl ester-d5**
γ-Linolenic acid ethyl ester-d₅ (Ethyl γ-linolenate-d₅) is the deuterium labeled γ-Linolenic acid ethyl ester (HY-108396). γ-Linolenic acid ethyl ester (Ethyl γ-linolenate) is a leukotriene B4 receptor 4 (LTB4) antagonist .

HY-W740965

Linolenic acid glycidyl ester-d5
Linolenic acid glycidyl ester-d₅ (9,12,15-Octadecatrienoic acid-d₅; Glycidyl linolenate-d₅) is the deuterium labeled Linolenic acid glycidyl ester (HY-W587910). Linolenic acid glycidyl ester (9,12,15-Octadecatrienoic acid; Glycidyl linolenate) is an ester product.

HY-21268S

Methyl linolenate-13C18
Methyl linolenate- ¹³C₁₈ is the ¹³C labeled Methyl linolenate . Methyl linolenate is a polyunsaturated fattly acid (PUFA). It is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids . The IC₅₀ is 60 uM .

HY-178424S

(Rac)-Jasmonic acid-d4
(Rac)-Jasmonic acid-d₄ is the deuterium labeled (Rac)-Jasmonic acid (HY-W317836). (Rac)-Jasmonic acid is the racemate of Jasmonic acid (HY-122464A). Jasmonic acid ((-)-Jasmonic acid) is a plant growth regulator and a derivative of Linolenic acid (HY-N0728) .

HY-21268S1

Methyl linolenate-13C17
Methyl linolenate-13C17 is an isotope-labeled fatty acid ester.

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