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  4. α-Linolenic acid sodium

α-Linolenic acid sodium  (Synonyms: ALA; C18:3 (9Z,12Z,15Z); C18:3 n-3)

Cat. No.: HY-N0728A Purity: 96.66%
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α-Linolenic acid sodium (ALA; C18:3 (9Z,12Z,15Z); C18:3 n-3) is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid sodium can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid sodium possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer.

For research use only. We do not sell to patients.

CAS No. : 822-18-4

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Based on 11 publication(s) in Google Scholar

Other Forms of α-Linolenic acid sodium:

α-Linolenic acid sodium Related Antibodies

Top Publications Citing Use of Products

    α-Linolenic acid sodium purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2025 Nov:147:157214.  [Abstract]

    α-Linolenic acid (ALA, 500 mg/kg; Oral gavage; Once daily for 8 weeks) treatment effectively reduced weight gain starting at week 4.

    α-Linolenic acid sodium purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2025 Nov:147:157214.  [Abstract]

    α-Linolenic acid (ALA, 500 mg/kg; Oral gavage; Once daily for 8 weeks) significantly inhibited the increase of FBG in mice starting from week 6.

    α-Linolenic acid sodium purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2025 Nov:147:157214.  [Abstract]

    The mRNA expression levels of inflammatory cytokines (TNF-α, IL-6, IL-17A, IFN-γ, IL-10, IL-1β and IL-18) in the liver of db/db mice were quantified by qRT-PCR. The results showed that, compared with the CO group, a significant decrease in liver TNF-α, IL-6, IL-17A, interferon-γ (IFN-γ), IL-1β, and IL-18 levels was observed in theα-Linolenic acid (ALA, 500 mg/kg; Oral gavage; Once daily for 8 weeks)-treated group.

    α-Linolenic acid sodium purchased from MedChemExpress. Usage Cited in: J Adv Res. 2024 May 7:S2090-1232(24)00183-8.  [Abstract]

    VIMTIN / K14, CD31 and FLT4 immunostaining shows angiogenesis after ALA (200 μM; s.c.) treatment in young mice; Statistics of CD31+ cells and FLT4+ cells. Scale bars, 50 μm.

    α-Linolenic acid sodium purchased from MedChemExpress. Usage Cited in: Redox Biol. 2023 Oct:66:102857.  [Abstract]

    Percentage of dead FHs74Int cells, treated with indicated PUFAs (20 or 40 μM) or/and Fer-1 (5 μM), detected at 120 h after irradiation. αLA: α-Linolenic acid (40 μM); LA: Linoleic acid; DHA: Docosahexaenoic acid; AA: Arachidonic acid.

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    Description

    α-Linolenic acid sodium (ALA; C18:3 (9Z,12Z,15Z); C18:3 n-3) is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid sodium can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid sodium possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].

    In Vitro

    α-Linolenic acid sodium converses into the longer chain fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    α-Linolenic acid sodium Related Antibodies
    In Vivo

    α-Linolenic acid (50-250 mg/kg; i.v., for 10 days) sodium can completely inhibit collagen- and adrenaline-induced thrombosis in mice at 250 mg/kg[1].
    α-Linolenic acid (35-175 mg/kg; i.v., for 10 days) sodium suppresses A-V thrombus formation in rats (weighing at 250 ~ 300 g)[1].
    α-Linolenic acid (70-175 mg/kg; i.v., for 10 days) sodium inhibits collagen stimulated platelet aggregation in rats[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Animal Model: Mice
    Dosage: 50, 100, 250 mg/kg
    Administration: i.v., 10 days
    Result: Inhibited collagen- and adrenaline-induced thrombosis in mice at 250 mg/kg.
    Clinical Trial
    Molecular Weight

    300.41

    Formula

    C18H29NaO2
    CAS No.
    Appearance

    Solid

    Color

    White to light yellow

    SMILES

    CC/C=C\C/C=C\C/C=C\CCCCCCCC(O[Na])=O
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    -20°C, sealed storage, away from moisture

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

    Purity & Documentation
    References
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    α-Linolenic acid sodium Related Classifications

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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    α-Linolenic acid822-18-4ALA C18:3 (9Z,12Z,15Z) C18:3 n-3Environmental PollutantsAktPI3KEnvironmental ContaminantsPKBProtein kinase BPhosphoinositide 3-kinaseSeedoilsessentialfattyacidthromboticanti-arrhythmiccardiovascularcancerInhibitorinhibitorinhibit

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