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Results for "

nitrogen

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (5) Adrenergic Receptor (1) Akt (11) Aldose Reductase (2) Amine N-methyltransferase (1) Amino Acid Derivatives (4) Aminopeptidase (1) Aminotransferases (Transaminases) (1) AMPK (2) Androgen Receptor (2) Angiotensin Receptor (1) Antibiotic (5) Antifolate (1) Apoptosis (18) Arginase (1) Autophagy (2) Bacterial (20) Beta-lactamase (1) Biochemical Assay Reagents (55) c-Myc (1) Cadherin (1) Carbonic Anhydrase (3) Caspase (1) Cathepsin (1) Cholinesterase (ChE) (3) Cytochrome P450 (2) Dihydrofolate reductase (DHFR) (2) DNA Alkylator/Crosslinker (14) DNA Stain (1) DNA/RNA Synthesis (8) Dopamine Receptor (1) Drug Derivative (12) Drug Intermediate (23) Drug Isomer (1) Drug Metabolite (2) EGFR (2) Endogenous Metabolite (81) Enteropeptidase (1) Environmental Pollutants (5) ERK (4) Estrogen Receptor/ERR (1) Factor Xa (1) Ferroptosis (1) Fluorescent Dye (45) Fungal (2) GABA Receptor (6) Galectin (2) Glutaminase (1) Glycosidase (1) Glycosyltransferase (1) Glyoxalase (GLO) (1) Histamine Receptor (9) Histone Methyltransferase (1) HSV (1) IFNAR (1) iGluR (6) Influenza Virus (1) Insecticide (3) Interleukin Related (1) Isotope-Labeled Compounds (33) JAK (1) Keap1-Nrf2 (1) Leukotriene Receptor (1) Lipocalin Family (1) Liposome (1) MicroRNA (1) Mitosis (1) MOFs (2) Monoamine Oxidase (3) mTOR (2) Neurokinin Receptor (1) NO Synthase (12) Nucleoside Antimetabolite/Analog (5) p38 MAPK (11) Parasite (4) Phosphodiesterase (PDE) (1) PI3K (1) Radionuclide-Drug Conjugates (RDCs) (2) RANKL/RANK (6) Reactive Oxygen Species (ROS) (29) Reference Standards (33) Renin (1) SOD (1) TNF Receptor (1) Toll-like Receptor (TLR) (6) Tyrosinase (14) Wnt (6) Xanthine Oxidase (1) β-catenin (6)
By Research Areas:	Cancer (86) Cardiovascular Disease (19) Endocrinology (13) Infection (31) Inflammation/Immunology (38) Metabolic Disease (71) Neurological Disease (46)
Click Chemistry:	Azide (4)
Oligonucleotides:	Adenosine (1) Nucleoside Analogs (2) Cationic Lipids (1) Antisense Oligonucleotides (1) Cytidine (1)

331

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GMP Molecules

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17420

Cyclophosphamide Maximum Cited Publications 69 Publications Verification	DNA Alkylator/Crosslinker	Cancer
Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant.

HY-B1204

Histamine 15+ Cited Publications Ergamine	Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite	Neurological Disease Inflammation/Immunology Endocrinology Cancer
Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .

HY-B1352

L-Ornithine 5+ Cited Publications (S)-2,5-Diaminopentanoic acid	Arginase Endogenous Metabolite	Metabolic Disease
L-Ornithine ((S)-2,5-Diaminopentanoic acid) is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine shows nephroprotective .

HY-108537

L 012 sodium salt 2 Publications Verification	Reactive Oxygen Species (ROS)	Inflammation/Immunology
L 012 sodium salt is a luminal-based chemiluminescent probe. L 012 sodium salt can detect NADPH oxidase (Nox)-derived superoxide and nitrogen species (reactive oxygen species (ROS) and reactive nitrogen species (RNS)) .

HY-17420A

Cyclophosphamide hydrate Maximum Cited Publications 69 Publications Verification Cyclophosphamide monohydrate	DNA Alkylator/Crosslinker	Cancer
Cyclophosphamide hydrate is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.

HY-Y0271

Urea 5+ Cited Publications Carbonyl diamide	Environmental Pollutants Apoptosis Endogenous Metabolite Carbonic Anhydrase ERK	Cardiovascular Disease Cancer
Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-Y0882

Hydroxylamine hydrochloride 1 Publications Verification	Monoamine Oxidase	Cardiovascular Disease
Hydroxylamine hydrochloride is a selective Monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine hydrochloride is an intermediate of nitrogen cycle in aerobic ammonium oxidizers microorganisms, such as ammonium oxidizing bacteria (AOB), ammonium oxidizing archaea (AOA) and complete ammonium oxidizing bacteria (comammox). Hydroxylamine hydrochloride impacts NO and N₂O emissions by aerobic ammonium oxidizers microorganisms and inhibits nitrite oxidizing bacteria (NOB) activity .

HY-B0722

Histamine dihydrochloride 15+ Cited Publications	Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite	Neurological Disease Inflammation/Immunology Endocrinology Cancer
Histamine dihydrochloride is the agonist for histamine receptor and a vasodilator. Histamine dihydrochloride is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine dihydrochloride affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine dihydrochloride can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .

HY-W017018

L-Ornithine hydrochloride 5+ Cited Publications	Endogenous Metabolite	Metabolic Disease
L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective .

HY-A0129

Histamine phosphate 15+ Cited Publications Histamine diphosphate	Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite	Neurological Disease Inflammation/Immunology Endocrinology Cancer
Histamine phosphate is the agonist for histamine receptor and a vasodilator. Histamine phosphate is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine phosphate affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine phosphate can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .

HY-15930

TMB 5+ Cited Publications BM blue; Sure Blue TMB	Fluorescent Dye MOFs Reactive Oxygen Species (ROS)	Others
TMB is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .

HY-Y0271S

Urea-15N2 Carbonyl diamide-¹⁵N₂	Endogenous Metabolite	Cardiovascular Disease Cancer
Urea- ¹⁵N₂ is the ¹⁵N-labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-150097

Recombinant Human Serum Albumin(rHSA)	Biochemical Assay Reagents	Metabolic Disease Inflammation/Immunology Cancer
Recombinant Human Serum Albumin (rHSA) is a non-glycosylated monomeric plasma protein that acts as a core factor for maintaining plasma colloid osmotic pressure. Recombinant Human Serum Albumin (rHSA) possesses multiple physiological functions including carrier, metabolic regulation, detoxification, antioxidation and enzyme mimicking. Recombinant Human Serum Albumin (rHSA) not only scavenges reactive oxygen and nitrogen species via specific residues and binds a variety of endogenous and exogenous compounds to maintain redox homeostasis, but also serves as a biomarker for multiple diseases such as cancer and inflammation. Recombinant Human Serum Albumin (rHSA) broadly supports the development of implantable materials, surgical adhesives and ligand capture, and can be used for research on critical illnesses including hypovolemia, liver failure, severe sepsis and various types of trauma resuscitation .

HY-D0827

Cy2 Cyanine2	Fluorescent Dye	Others
Cyanines are formally compounds with two nitrogen atoms linked by an odd number of methene units. 26 28 The nitrogen atoms are parts of the heterocyclic units (such as indole, benzoxazol, or benzothiazol) . The structures and optical properties of representative cyanine dyes used for in vivo imaging are presented . Cyanines are characterized by long wavelength, tunable absorption and emission, very high extinction coefficient (up to 300,000 M 1 cm 1), good water solubility, and relatively straightforward synthesis .

HY-118315

L-012 2 Publications Verification	Fluorescent Dye	Inflammation/Immunology
L-012 is a luminal-based chemiluminescent probe. L-012 sodium salt can detect NADPH oxidase (Nox)-derived superoxide and nitrogen species (reactive oxygen species (ROS) and reactive nitrogen species (RNS)) .

HY-W013040

Pyrazine 1,4-Diazine	MOFs Drug Intermediate	Cardiovascular Disease Infection Inflammation/Immunology Cancer
Pyrazine is an aromatic nitrogen-containing heterocyclic compound with two nitrogen atoms, and is well known for its electron-deficient property. Pyrazine serves as a key pharmacophore in a variety of drugs, and also acts as the core skeleton of derivatives with anticancer, antimycobacterial, antithrombotic and anti-inflammatory activities .

HY-Y0271S2

Urea-13C,15N2 Carbonyl diamide-¹³C,¹⁵N₂	Endogenous Metabolite	Cardiovascular Disease
Urea- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Urea . Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-15930A

TMB dihydrochloride 5+ Cited Publications BM blue dihydrochloride; Sure Blue TMB dihydrochloride	Fluorescent Dye Reactive Oxygen Species (ROS)	Others
TMB dihydrochloride is the dihydrochloride form of TMB (HY-15930). TMB dihydrochloride is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB dihydrochloride can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB dihydrochloride can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .

HY-59261

2-Amino-5-bromopyrazine	Biochemical Assay Reagents	Others
2-Amino-5-bromopyrazine is a monobrominated 2-aminopyrazine derivative and functionalized intermediate for the synthesis of nitrogen heterocycles .

HY-W133891

Peptone from soya Peptones, soybean	Biochemical Assay Reagents	Others
Peptone from soy (peptones, soybean) is a peptone. Peptone from soy provides nitrogen and carbon sources, as well as other nutrients. Peptone from soy can stimulate/regulate the biosynthesis of cyclic eicosanoids. Peptone from soy induces dose-dependent contraction of guinea pig lung parenchyma. Peptone from soy can be used in microbial and cell culture .

HY-W018800

4(3H)-Quinazolinone 1 Publications Verification	Bacterial EGFR	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
4(3H) -quinazolinone is a fused nitrogen heterocyclic compound whose derivatives have a wide range of antimicrobial and antitumor activities .

HY-114516

Fructosylvaline	Endogenous Metabolite	Metabolic Disease
Fructosylvaline (Fructose Valine) is a model fructosyl-amine (Amadori compound) for glycated hemoglobin. Fructosylvaline can be used as a nitrogen source to cultivate microbial strains .

HY-B1529A

Citric acid triammonium 5+ Cited Publications Triammonium citrate	Apoptosis Endogenous Metabolite Bacterial	Others Cancer
Citric acid triammonium (Triammonium citrate) is formed by Citric acid (HY-N1428) reacting with ammonia in a molar ratio of 1:3. Citric acid triammonium can be used as the carbon source to prepare carbon quantum dots (CDs). Citric acid triammonium with higher nitrogen components might promote the nitrogen-based functional groups in CDs, leading to a more efficient emission-color tunability .

HY-Y0882S1

Hydroxylamine-d3 hydrochloride	Monoamine Oxidase	Cardiovascular Disease
Hydroxylamine-d₃ (hydrochloride) is the deuterium labeled Hydroxyamine hydrochloride. Hydroxylamine hydrochloride is a selective Monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine hydrochloride is an intermediate of nitrogen cycle in aerobic ammonium oxidizers microorganisms, such as ammonium oxidizing bacteria (AOB), ammonium oxidizing archaea (AOA) and complete ammonium oxidizing bacteria (comammox). Hydroxylamine hydrochloride impacts NO and N₂O emissions by aerobic ammonium oxidizers microorganisms and inhibits nitrite oxidizing bacteria (NOB) activity .

HY-W587907

5-Formylcytidine	Drug Derivative	Others
5-Formylcytosine is a pyrimidine nitrogen base derived from cytosine .

HY-Y0271S1

Urea-d4 Carbonyl diamide-d₄	Endogenous Metabolite	Others
Urea-d₄ is the deuterium labeled Urea . Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-D1895A

3,5-DiBr-PAESA sodium	Biochemical Assay Reagents	Others
3,5-DiBr-PAESA sodium is a water-soluble pyridylazo-based highly sensitive chromogenic reagent. With the assistance of EDTA for masking copper and bromide ions for dissociating silver chelates, 3,5-DiBr-PAESA sodium enables accurate determination of sub-milligram level silver ions in strongly acidic high-copper systems via flow injection spectrophotometry .

HY-W000438

N-Boc-O-tosyl hydroxylamine	Amino Acid Derivatives	Others
N-Boc-O-tosyl hydroxylamine is a safe and efficient nitrogen source for N-amination of aryl and alkyl amines. N-Boc-O-tosyl hydroxylamine promotes electrophilic N-amination of aryl amines and alkyl amines to generate β-Boc-protected aryl hydrazines and alkyl hydrazines .

HY-16405

PR-104	DNA Alkylator/Crosslinker	Cancer
PR-104 is a selective hypoxia-activated DNA cross-linking agent and can be used for the research of multiple tumor xenograft models. PR-104, as a nitrogen mustard pre-proagent, is converted efficiently to the more lipophilic dinitrobenzamide mustards alcohol PR-104A .

HY-W012898

Dimethylglyoxime Biacetyl dioxime	Biochemical Assay Reagents	Others
Dimethylglyoxime (Biacetyl dioxime) belongs to the class of oximes and consists of two acetyl groups attached to a nitrogen atom, which in turn is attached to another nitrogen atom through a diimine bond. Dimethylglyoxime is a specific chelator of Ni that inhibits or slows the aggregation of Aβ peptides in vitro .

HY-D0705

Acid Yellow 9 monosodium salt Hydrogen 4-aminoazobenzene-3,4'-disulphonate sodium salt	Fluorescent Dye	Others
Acid Yellow 9 monosodium salt is an azo dye, degraded by Pseudomonas fluorescens as sole source of carbon, nitrogen and energy for the bacterium .

HY-D1895

3,5-DiBr-PAESA	Biochemical Assay Reagents	Others
3,5-DiBr-PAESA is a water-soluble pyridylazo-based highly sensitive chromogenic reagent. With the assistance of EDTA for masking copper and bromide ions for dissociating silver chelates, 3,5-DiBr-PAESA enables accurate determination of sub-milligram level silver ions in strongly acidic high-copper systems via flow injection spectrophotometry .

HY-17420S

Cyclophosphamide-d4	DNA Alkylator/Crosslinker	Cancer
Cyclophosphamide-d₄ is the deuterium labeled Cyclophosphamide. Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant .

HY-W017018S

L-Ornithine-d6 hydrochloride	Endogenous Metabolite	Metabolic Disease
L-Ornithine-d₆ (hydrochloride) is the deuterium labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-W017018S4

L-Ornithine-d7 hydrochloride	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
L-Ornithine-d₇ (hydrochloride) is the deuterium labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-W017018B

L-Ornithine monohydrochloride,suitable for cell culture	Biochemical Assay Reagents	Others
L-Ornithine monohydrochloride, suitable for cell culture is a non-proteinogenic amino acid that is mainly used in the urea cycle to remove excess nitrogen from the body and can be used for cell culture .

HY-157347A

*Yeast Nitrogen* Base Medium without Amino Acids** YNB Medium without Amino Acids	Biochemical Assay Reagents	Others
Yeast Nitrogen Base Medium without Amino Acids can be used in the cultivation of bacteria in genetic engineering .

HY-172314

ACHM-025	Aldose Reductase Drug Derivative	Cancer
ACHM-025 is a prodrug, which is selectively activated by AKR1C3 to a nitrogen mustard DNA alkylating agent. ACHM-025 can be used for the research of cancer, such as leukemia .

HY-W587486R

N-Acetyltaurine (Standard)	Reference Standards Endogenous Metabolite Bacterial	Neurological Disease
N-Acetyltaurine (Standard) is the analytical standard of N-Acetyltaurine (HY-W587486). This product is intended for research and analytical applications. N‑acetyltaurine is an orally active endogenous sulfonate that is synthesized from taurine and acetate in the renal cortex. N‑acetyltaurine supports bacterial growth as a sole fixed nitrogen or carbon source. N‑acetyltaurine buffers acetyl moieties of mitochondrial acetyl‑CoA in skeletal muscle. N‑acetyltaurine reduces food intake and body weight in obese and lean wild‑type mice in a GFRAL‑dependent manner. N‑acetyltaurine can be used for the research of diet‑induced obesity, hyperacetatemia and diabetes .

HY-B1204R

Histamine (Standard) Ergamine (Standard)	Reference Standards Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite	Neurological Disease Inflammation/Immunology Endocrinology Cancer
Histamine (Standard) is the analytical standard of Histamine (HY-B1204). This product is intended for research and analytical applications. Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .

HY-B0722R

Histamine dihydrochloride (Standard)	Reference Standards Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite	Neurological Disease Inflammation/Immunology Endocrinology Cancer
Histamine dihydrochloride (Standard) is the analytical standard of Histamine dihydrochloride (HY-B0722). This product is intended for research and analytical applications. Histamine dihydrochloride is the agonist for histamine receptor and a vasodilator. Histamine dihydrochloride is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine dihydrochloride affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine dihydrochloride can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .

HY-P4545

*Abz-Gly-p-nitro-Phe-Pro-OH*	Angiotensin Receptor	Others
Abz-Gly-p-nitro-Phe-Pro-OH is the fluorescent substrate angiotensin I converting enzyme (ACE-I) with 355 nm excitation and 405 nm emission wavelengths .

HY-Y0271R

Urea (Standard) Carbonyl diamide (Standard)	Carbonic Anhydrase Reference Standards Endogenous Metabolite ERK Apoptosis	Cardiovascular Disease Cancer
Urea (Standard) is the analytical standard of Urea. This product is intended for research and analytical applications. Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-17420AR

Cyclophosphamide hydrate (Standard) Cyclophosphamide monohydrate (Standard)	Reference Standards DNA Alkylator/Crosslinker	Cancer
Cyclophosphamide (hydrate) (Standard) is the analytical standard of Cyclophosphamide (hydrate). This product is intended for research and analytical applications. Cyclophosphamide hydrate is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.

HY-157347

*Yeast Nitrogen* Base Medium** YNB Medium	Biochemical Assay Reagents	Others
Yeast Nitrogen Base Medium (YNB Medium) is a yeast-specific medium. Yeast Nitrogen Base Medium can be used for microbial culture. The composition of 100 mL of the medium is as follows: 6.7 g Yeast Nitrogen Base Medium and 5 g D-Glucose (HY-B0389) or other carbohydrates .

HY-W040209

2-(Naphthalen-1-yl)-5-phenyloxazole α-NPO	Fluorescent Dye	Others
2-(Naphthalen-1-yl)-5-phenyloxazole (α-NPO) is an organic fluorescent dye. 2-(Naphthalen-1-yl)-5-phenyloxazole has a nitrogen atom in its structure that can interfere with the nitrogen content from the amination step .

HY-W017018R

L-Ornithine hydrochloride (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
L-Ornithine (hydrochloride) (Standard) is the analytical standard of L-Ornithine (hydrochloride). This product is intended for research and analytical applications. L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective .

HY-B1204S1

Histamine-d4 Ergamine-d₄	Isotope-Labeled Compounds Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite	Neurological Disease Inflammation/Immunology Endocrinology Cancer
Histamine-d₄ (Ergamine-d₄) is deuterium labeled Histamine (HY-B1204). Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .

HY-P4561

*H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH*	Cathepsin	Others
H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen. H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH has potential applications in biochemical analysis .

HY-136559

6-Azathymine	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Bacterial Influenza Virus	Infection
6-Azathymine, a 6-nitrogen analog of thymine, is a potent D-3-aminoisobutyrate-pyruvate aminotransferase inhibitor. 6-Azathymine inhibits the biosynthesis of DNA, and has antibacterial and antiviral activities .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1204

Histamine 15+ Cited Publications Ergamine	Structural Classification Natural Products Human Gut Microbiota Metabolites Neurological Disease Classification of Application Fields Endogenous metabolite Disease Research Fields Endocrinology Cancer	Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite
Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .

HY-W013636

2-Ketoglutaric acid 5+ Cited Publications Alpha-Ketoglutaric acid; 2-Oxoglutaric acid	Immune System Disorder Microorganisms Classification of Application Fields Anti-aging Ketones, Aldehydes, Acids Disease markers Other Diseases Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Source Classification	Tyrosinase Endogenous Metabolite
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-B1352

L-Ornithine 5+ Cited Publications (S)-2,5-Diaminopentanoic acid	Classification of Application Fields Anti-aging Ketones, Aldehydes, Acids Disease markers Other Diseases Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Cardiovascular System Disorder Source Classification	Arginase Endogenous Metabolite
L-Ornithine ((S)-2,5-Diaminopentanoic acid) is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine shows nephroprotective .

HY-Y0271

Urea 5+ Cited Publications Carbonyl diamide	Structural Classification Natural Products Microorganisms Classification of Application Fields Endogenous metabolite Disease Research Fields Biological Pesticide Research Source Classification Cancer Agricultural Research	Environmental Pollutants Apoptosis Endogenous Metabolite Carbonic Anhydrase ERK
Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-B0722

Histamine dihydrochloride 15+ Cited Publications	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite
Histamine dihydrochloride is the agonist for histamine receptor and a vasodilator. Histamine dihydrochloride is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine dihydrochloride affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine dihydrochloride can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .

HY-W017018

L-Ornithine hydrochloride 5+ Cited Publications	Microorganisms Classification of Application Fields Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective .

HY-A0129

Histamine phosphate 15+ Cited Publications Histamine diphosphate	Alkaloids Neurological Disease Classification of Application Fields Other Alkaloids Endogenous metabolite Disease Research Fields Endocrinology Source Classification Cancer	Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite
Histamine phosphate is the agonist for histamine receptor and a vasodilator. Histamine phosphate is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine phosphate affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine phosphate can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .

HY-126854

N-Acetyllactosamine N-Acetyl-D-lactosamine	Natural Products Microorganisms	Endogenous Metabolite Galectin
N-Acetyllactosamine (N-Acetyl-D-lactosamine), a nitrogen-containing disaccharide, is a galectin-3 inhibitor, which is an important component of various oligosaccharides such as glycoproteins and sialyl Lewis X. N-Acetyllactosamine can be used as the starting material for the synthesis of various oligosaccharides. N-Acetyllactosamine has prebiotic effects .

HY-B0504

Creatinine 5+ Cited Publications NSC13123	Infection Structural Classification Natural Products Classification of Application Fields Disease markers Endocrine diseases Metabolic Disease Nervous System Disorder Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite GABA Receptor iGluR
Creatinine (NSC13123) is an orally active, blood-brain barrier-permeable modulator of GABAA and NMDA receptors, with activities of antioxidation and metabolic regulation. Creatinine is generated via non-enzymatic conversion of creatine and phosphocreatine in muscle. Creatinine serum levels correlate with muscle mass, glomerular filtration rate, and extrarenal clearance, serving as an evaluation biomarker for renal function, muscle mass, and clinical outcomes, and used for perioperative renal risk assessment. In addition, Creatinine can induce specific Cryptococcus species to produce creatinine deiminase and act as their nitrogen source, while it can be secreted via renal tubules. Creatinine is widely used in research related to various diseases such as neurodegenerative diseases, psychiatric disorders, acute kidney injury, chronic kidney disease, and renal failure .

HY-W008150

2-Hydroxy-3-methylbutanoic acid 1 Publications Verification α-Hydroxyisovaleric acid	Structural Classification Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Source Classification	Endogenous Metabolite
2-Hydroxy-3-methylbutanoic acid (α-Hydroxyisovaleric acid) is an α-hydroxy analogue of valine and a valine precursor that reduces urea excretion. 2-Hydroxy-3-methylbutanoic acid can promote the growth of chickens and rats, and is converted into valine in the body, participating in protein synthesis and maintaining nitrogen balance, thereby supporting animal growth and development. 2-Hydroxy-3-methylbutanoic acid has a more significant effect on the valine-deficient dietary model. 2-Hydroxy-3-methylbutanoic acid is mainly used in animal nutrition research to evaluate its potential application as a nitrogen source substitute in feed .

HY-D0168

Orcinol 3,5-Dihydroxytoluene	Microorganisms Classification of Application Fields Other Diseases Phenols Polyphenols Ericaceae Plants Disease Research Fields Source Classification	Fluorescent Dye Tyrosinase p38 MAPK ERK
Orcinol (3,5-Dihydroxytoluene) is an organic compound used in biological dyeing and proteomics research. Orcinol inhibits melanogenesis in B16F10 cells by upregulating the MAPK/ERK signaling pathway, and suppresses the expression of MITF, tyrosinase (TYR), TRP1, and DCT. Orcinol exhibits certain DPPH radical scavenging activity. In addition, Orcinol can alter nitrogen balance in animals. Orcinol holds promise for research in cancer and metabolic diseases .

HY-N0455B

L-Arginine (L-glutamate) Maximum Cited Publications 23 Publications Verification (S)-(+)-Arginine (L-glutamate)	Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Endogenous Metabolite NO Synthase
L-Arginine L-glutamate ((S)-(+)-Arginine L-glutamate) is the nitrogen donor for synthesis of nitric oxide. L-Arginine L-glutamate can be used for upper gastrointestinal hypofunction or dysfunction like functional dyspepsia research .

HY-W013636A

2-Ketoglutaric acid Sodium 5+ Cited Publications Alpha-Ketoglutaric acid Sodium	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Tyrosinase Endogenous Metabolite
2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W018800

4(3H)-Quinazolinone 1 Publications Verification	Structural Classification Neurological Disease Classification of Application Fields Metabolic Disease Quinoline Alkaloids Plants Infection Alkaloids Acanthaceae Disease Research Fields Endocrinology Jacobaea cannabifolia (Less.) E. Wiebe Source Classification	Bacterial EGFR
4(3H) -quinazolinone is a fused nitrogen heterocyclic compound whose derivatives have a wide range of antimicrobial and antitumor activities .

HY-W012161

Alanylphenylalanine L-Alanyl-L-phenylalanine; H-Ala-Phe-OH	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Drug Intermediate
Alanylphenylalanine (L-Alanyl-L-phenylalanine) is a dipeptide. Alanylphenylalanine forms a mononuclear Au (III) complex through bidentate coordination via its carboxyl oxygen atom and deprotonated amide nitrogen atom .

HY-N0391A

L-Citrulline DL-malate 5+ Cited Publications	Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Endogenous Metabolite
L-Citrulline (DL-malate) is an organic compound commonly used as a nutritional supplement. It boosts the body's production of nitrogen oxides, improves circulation and athletic performance, and reduces muscle fatigue. In addition, L-Citrulline DL-malate also plays an important role in some industrial fields, for example, it is used in the field of agriculture to enhance plant immunity.

HY-B0504R

Creatinine (Standard) NSC13123 (Standard)	Infection Structural Classification Natural Products Microorganisms Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite iGluR GABA Receptor
Creatinine (Standard) is the analytical standard of Creatinine. This product is intended for research and analytical applications. Creatinine (NSC13123) is an orally active, blood-brain barrier-permeable modulator of GABAA and NMDA receptors, with activities of antioxidation and metabolic regulation. Creatinine is generated via non-enzymatic conversion of creatine and phosphocreatine in muscle. Creatinine serum levels correlate with muscle mass, glomerular filtration rate, and extrarenal clearance, serving as an evaluation biomarker for renal function, muscle mass, and clinical outcomes, and used for perioperative renal risk assessment. In addition, Creatinine can induce specific Cryptococcus species to produce creatinine deiminase and act as their nitrogen source, while it can be secreted via renal tubules. Creatinine is widely used in research related to various diseases such as neurodegenerative diseases, psychiatric disorders, acute kidney injury, chronic kidney disease, and renal failure .

HY-Y0519

Pyrimidine	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Pyrimidine is a nitrogen-containing heterocyclic compound and endogenous metabolite. Pyrimidine derivatives can be used in pancreatic cancer, triple-negative breast cancer, colon carcinoma and neuron research .

HY-W013636B

Calcium 2-oxoglutarate 5+ Cited Publications	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Tyrosinase Endogenous Metabolite
Calcium 2-oxoglutarate is an intermediate in the production of ATP or GTP in the Krebs cycle. Calcium 2-oxoglutarate also acts as the major carbon skeleton for nitrogen-assimilatory reactions. Calcium 2-oxoglutarate is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W010378

D-Asparagine H-D-Asn-OH	Structural Classification Classification of Application Fields Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
D-Asparagine (H-D-Asn-OH) acts as a competitive inhibitor of L-asparagine hydrolysis, with a K_i value of 0.24 mM. D-Asparagine serves as a nitrogen source for yeast strains. D-Asparagine is a good substrate for external yeast asparaginase but a poor substrate for internal yeast asparaginase .

HY-111806

3,7,4'-Trihydroxyflavone 2 Publications Verification 5-Deoxykampferol; Resokaempferol	Flavonols Classification of Application Fields Rhus chinensis Mill. Plants Flavonoids Simaroubaceae Other Diseases Phenols Polyphenols Disease Research Fields Brucea javanica (L.) Merr. Anacardiaceae Source Classification	Reactive Oxygen Species (ROS) Leukotriene Receptor DNA/RNA Synthesis
3,7,4'-Trihydroxyflavone (5-Deoxykampferol) is a flavonoid compound that can be isolated from the stems of Rhus javanica var. roxburghiana. 3,7,4'-Trihydroxyflavone has the effect of cleaving DNA in the presence of copper ions. 3,7,4'-Trihydroxyflavone also has anti-inflammatory and antioxidant activities and can scavenge various reactive oxygen species (ROS) and reactive nitrogen species (RNS) .

HY-W037619

Pteridine-2,4(1H,3H)-dione	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Biochemical Assay Reagents
Pteridine-2,4 (1H,3H)-dione is a pteridine derivative (xanthopterin) and a sulfur-containing pteridine compound (2,4-dimercaptopyrimidine). Pteridine-2,4 (1H,3H)-dione possesses metal-binding ability, and forms closed-shell (ionic) interactions with palladium via sulfur and nitrogen atoms. Pteridine-2,4 (1H,3H)-dione derivates can be used in studies related to neuroblastoma, glioma and breast cancer .

HY-121262

Bisabolene (mixture of isomers) 1 Publications Verification Bisabolene; γ-Bisabolene	Other Terpenoids Structural Classification Microorganisms Terpenoids Source Classification	Drug Intermediate
Bisabolene (mixture of isomers) (Bisabolene) is a sesquiterpenoid plant natural product and also a hydrocarbon precursor for various industry-relevant chemicals. Bisabolene (mixture of isomers) serves as an important precursor for the production of industry-relevant chemicals such as biofuels, bioplastics, pharmaceuticals and cosmetics .

HY-B1204R

Histamine (Standard) Ergamine (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite	Reference Standards Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite
Histamine (Standard) is the analytical standard of Histamine (HY-B1204). This product is intended for research and analytical applications. Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .

HY-B0722R

Histamine dihydrochloride (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite
Histamine dihydrochloride (Standard) is the analytical standard of Histamine dihydrochloride (HY-B0722). This product is intended for research and analytical applications. Histamine dihydrochloride is the agonist for histamine receptor and a vasodilator. Histamine dihydrochloride is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine dihydrochloride affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine dihydrochloride can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .

HY-Y0271R

Urea (Standard) Carbonyl diamide (Standard)	Structural Classification Natural Products Microorganisms Endogenous metabolite Source Classification	Carbonic Anhydrase Reference Standards Endogenous Metabolite ERK Apoptosis
Urea (Standard) is the analytical standard of Urea. This product is intended for research and analytical applications. Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-123894

Pelargonidin 3,5-diglucoside chloride	Anthocyans Flavonoids Hyacinthus orientalis L. Sp. Pl. Plants Source Classification Asparagaceae Juss.	Reactive Oxygen Species (ROS)
Pelargonidin 3,5-diglucoside (chloride) is a natural pigment abundantly present in red fruits and vegetables. Pelargonidin 3,5-diglucoside (chloride) acts as a scavenger for reactive oxygen species and *reactive nitrogen* species . Pelargonidin 3,5-diglucoside (chloride) demonstrates inhibitory effects on enzymes involved in the production of ROS, RNS**, and pro-inflammatory cytokines .

HY-W013636R

2-Ketoglutaric acid (Standard) 5+ Cited Publications Alpha-Ketoglutaric acid (Standard); 2-Oxoglutaric acid (Standard)	Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Source Classification	Reference Standards Tyrosinase Endogenous Metabolite
2-Ketoglutaric acid (Standard) (Alpha-Ketoglutaric acid (Standard)) is the analytical standard of 2-Ketoglutaric acid (HY-W013636). This product is intended for research and analytical applications. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W017018R

L-Ornithine hydrochloride (Standard)	Structural Classification Microorganisms Amino acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
L-Ornithine (hydrochloride) (Standard) is the analytical standard of L-Ornithine (hydrochloride). This product is intended for research and analytical applications. L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective .

HY-Y0519R

Pyrimidine (Standard)	Structural Classification Natural Products Microorganisms Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Pyrimidine (Standard) is the analytical standard of Pyrimidine. This product is intended for research and analytical applications. Pyrimidine is a nitrogen-containing heterocyclic compound and endogenous metabolite. Pyrimidine derivatives can be used in pancreatic cancer, triple-negative breast cancer, colon carcinoma and neuron research .

HY-W008150R

2-Hydroxy-3-methylbutanoic acid (Standard) α-Hydroxyisovaleric acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
2-Hydroxy-3-methylbutanoic acid (α-Hydroxyisovaleric acid) (Standard) is the analytical standard of 2-Hydroxy-3-methylbutanoic acid (HY-W008150). This product is intended for research and analytical applications. 2-Hydroxy-3-methylbutanoic acid is an α-hydroxy analogue of valine and a valine precursor that reduces urea excretion. 2-Hydroxy-3-methylbutanoic acid can promote the growth of chickens and rats, and is converted into valine in the body, participating in protein synthesis and maintaining nitrogen balance, thereby supporting animal growth and development. 2-Hydroxy-3-methylbutanoic acid has a more significant effect on the valine-deficient dietary model. 2-Hydroxy-3-methylbutanoic acid is mainly used in animal nutrition research to evaluate its potential application as a nitrogen source substitute in feed.

HY-W018800R

4(3H)-Quinazolinone (Standard)	Alkaloids Structural Classification Acanthaceae Quinoline Alkaloids Plants Jacobaea cannabifolia (Less.) E. Wiebe Source Classification	Reference Standards Bacterial EGFR
4(3H) -quinazolinone is a fused nitrogen heterocyclic compound whose derivatives have a wide range of antimicrobial and antitumor activities .

HY-113289R

Brassicasterol (Standard)	Animals Steroids Source Classification	Akt Androgen Receptor Bacterial Drug Metabolite HSV Reference Standards
L-Ornithine (hydrochloride) (Standard) is the analytical standard of L-Ornithine (hydrochloride). This product is intended for research and analytical applications. L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective .

HY-121348

Ficellomycin U-47929	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial DNA/RNA Synthesis
Ficellomycin is a nitrogen-containing bicyclic antibiotic with strong activity against Gram-positive bacteria, including multidrug-resistant strains of Staphylococcus aureus. Ficellomycin works by inducing the formation of defective 34S DNA fragments, which interfere with the semi-conservative DNA replication process. These fragments lack the ability to integrate into larger DNA segments and eventually form a complete bacterial chromosome. Ficellomycin can be used in research for various bacterial diseases .

HY-A0129R

Histamine phosphate (Standard) Histamine diphosphate (Standard)	Alkaloids Structural Classification Other Alkaloids Endogenous metabolite Source Classification	Reference Standards Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite
Histamine phosphate (Standard) is the analytical standard of Histamine phosphate (HY-A0129). This product is intended for research and analytical applications. Histamine phosphate is the agonist for histamine receptor and a vasodilator. Histamine phosphate is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine phosphate affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine phosphate can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .

HY-N14679

Pinselin	Natural Products Microorganisms Source Classification	Antibiotic Fungal
Pinselin is a nitrogen-containing heterocyclic antibiotic. Pinselin has anti-yeast activity .

HY-N14587

Oxypyrrolnitrin	Natural Products Microorganisms Source Classification	Antibiotic Bacterial
Oxypyrrolnitrin is a nitrogen-containing heterocyclic antibiotic. Oxypyrrolnitrin has anti-Gram-positive bacteria, negative bacteria, mycobacterium and fungal effects .

HY-N9355

(+)-N-Formylnorglaucine	Alkaloids other families Classification of Application Fields Other Diseases Plants Isoquinoline Alkaloids Disease Research Fields Source Classification	Others
(+)-N-Formylnorglaucine is an aporphine alkaloid isolated from the leaves of Unonopsis stipitata. (+)-N-Formylnorglaucine contains a formyl group linked to the heterocyclic nitrogen .

HY-17564R

2'-Deoxycytidine hydrochloride (Standard) 2'-Deoxycytidine monohydrochloride (Standard); Deoxycytidine hydrochloride (Standard); NSC 83251 (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Nucleoside Antimetabolite/Analog
2'-Deoxycytidine (hydrochloride) (Standard) is an analytical standard for 2'-Deoxycytidine (hydrochloride). This product is intended for research and analytical applications. 2'-Deoxycytidine hydrochloride is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose.

HY-126854R

N-Acetyllactosamine (Standard) N-Acetyl-D-lactosamine (Standard)	Structural Classification Natural Products Microorganisms	Reference Standards Endogenous Metabolite Galectin
N-Acetyllactosamine (Standard) is the analytical standard of N-Acetyllactosamine. This product is intended for research and analytical applications. N-Acetyllactosamine (N-Acetyl-D-lactosamine), a nitrogen-containing disaccharide, is a galectin-3 inhibitor, which is an important component of various oligosaccharides such as glycoproteins and sialyl Lewis X. N-Acetyllactosamine can be used as the starting material for the synthesis of various oligosaccharides. N-Acetyllactosamine has prebiotic effects[1][2][3][4].

HY-W013636AR

2-Ketoglutaric acid Sodium (Standard) Alpha-Ketoglutaric acid Sodium (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Tyrosinase Endogenous Metabolite
2-Ketoglutaric acid (Sodium) (Standard) is the analytical standard of 2-Ketoglutaric acid Sodium (HY-W013636A). This product is intended for research and analytical applications. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) Sodium (Standard) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-N15587

Gostatin Gostatine	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source Classification	Aminotransferases (Transaminases)
Gostatin is an inhibitor of aspartate aminotransferase (GOT). Gostatin is found in Streptomyces sumanensis nov. sp. NK-23. Gostatin has a strong inhibitory effect on pig heart GOT, a weak inhibitory effect on wheat germ GOT and GPT, and no significant effect on glutamate dehydrogenase and glutamine synthetase. The inhibitory mechanism of gostatin is similar to substrate competitive inhibition, and aspartate has a protective effect on its inhibitory effect. Gostatin can be used to study the catalytic mechanism of GOT and its role in nitrogen metabolism .

HY-N15791

Cyanine 3.5 maleimide chloride	Structural Classification Lipid	Fluorescent Dye
Cyanine3.5 maleimide chloride is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .

HY-N16328

Cyanine 7.5 maleimide chloride	Structural Classification Lipid	Fluorescent Dye
Cy7.5 maleimide chloride is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .

HY-N15353

1-Palmitoyl-2-linoleoyl-sn-glycerol	Structural Classification Plants Cycadaceae Cycas revoluta Thunb. Lipid Source Classification	Bacterial
1-Palmitoyl-2-linoleoyl-sn-glycerol is a diacylglycerol (DAG)-type lipid signaling molecule found in the coralloid roots of Cycas revoluta, and serves as a major active component of the plant-secreted hormogonium-inducing factor (HIF). At a concentration of 1 nmol/disc (approximately 0.6 µg), 1-palmitoyl-2-linoleoyl-sn-glycerol can significantly induce the differentiation of filamentous aggregates of Nostoc into motile hormogonia, thereby promoting chemotaxis toward host roots and the establishment of symbiosis. This compound holds significant research and application potential in areas such as plant–microbe interactions, rhizosphere signaling pathways, and nitrogen-fixing symbiosis .

HY-113593

GSK1360707	Oleaceae Forsythia suspensa (Thunb.) Vahl Plants Source Classification	Biochemical Assay Reagents
GSK1360707 is a triple uptake inhibitor targeting nitrogen and olefin substitution reactions.

HY-N18353

Hexadesacetyleuomynine	Structural Classification Ketones, Aldehydes, Acids Celastraceae Tripterygium wilfordii Hook. f. Plants Source Classification	Drug Derivative
Hexadesacetyleuomynine (Compound 15) is a nitrogen-containing dihydroagarofuran derivative found in the dried roots of Tripterygium wilfordii .

HY-135015

Tetradecanenitrile	Structural Classification Natural Products Michelia champaca L. Magnoliaceae Plants Lipid Steroids Source Classification	Endogenous Metabolite
Tetradecanenitrile is a nitrogen-containing saturated long-chain aliphatic nitrile that can be found in Pseudomonas veronii R02. Tetradecanenitrile can be used for the research of multiresistant Staphylococcus aureus infection .

HY-118572

(S)-Allantoin	Structural Classification Caprifoliaceae Cordyceps bassiana Ketones, Aldehydes, Acids Plants Endogenous metabolite Source Classification	Drug Isomer
(S)-Allantoin is the S-isomer of Allantoin (HY-N0543). (S)-Allantoin binds selectively in the active site of urate oxidase. (S)-Allantoin can be converted to Allantoate by the action of allantoicase. (S)-Allantoin serves as a source of nitrogen in Arabidopsis thaliana .

HY-W012161R

Alanylphenylalanine (Standard) L-Alanyl-L-phenylalanine (Standard); H-Ala-Phe-OH (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards
Alanylphenylalanine (L-Alanyl-L-phenylalanine) Standard is the analytical standard of Alanylphenylalanine (HY-W012161). This product is intended for research and analytical applications. Alanylphenylalanine (L-Alanyl-L-phenylalanine) is a dipeptide. Alanylphenylalanine forms a mononuclear Au (III) complex through bidentate coordination via its carboxyl oxygen atom and deprotonated amide nitrogen atom .

Cat. No.	Product Name	Chemical Structure

HY-N0455AS8

L-Arginine-13C6,15N4 hydrochloride
L-Arginine- ¹³C₆, ¹⁵N₄ (hydrochloride) is the ¹³C- and ¹⁵N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-B0504S

Creatinine-d3

5 Publications Verification

Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine (NSC13123) is an orally active, blood-brain barrier-permeable modulator of GABAA and NMDA receptors, with activities of antioxidation and metabolic regulation. Creatinine is generated via non-enzymatic conversion of creatine and phosphocreatine in muscle. Creatinine serum levels correlate with muscle mass, glomerular filtration rate, and extrarenal clearance, serving as an evaluation biomarker for renal function, muscle mass, and clinical outcomes, and used for perioperative renal risk assessment. In addition, Creatinine can induce specific Cryptococcus species to produce creatinine deiminase and act as their nitrogen source, while it can be secreted via renal tubules. Creatinine is widely used in research related to various diseases such as neurodegenerative diseases, psychiatric disorders, acute kidney injury, chronic kidney disease, and renal failure .

HY-W013636S

2-Ketoglutaric acid-13C5

2-Ketoglutaric acid- ¹³C₅ (Alpha-Ketoglutaric acid- ¹³C₅) is a ¹³C labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-Y0271S

Urea-15N2
Urea- ¹⁵N₂ is the ¹⁵N-labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-N0455AS2

L-Arginine-d7 hydrochloride
L-Arginine-d₇ (hydrochloride) is the deuterium labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-N0455AS6

L-Arginine-13C6 hydrochloride
L-Arginine- ¹³C₆ (hydrochloride) is the ¹³C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-N0455AS1

L-Arginine-15N4 hydrochloride
L-Arginine- ¹⁵N₄ (hydrochloride) is the ¹⁵N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis .

HY-B0504S2

Creatinine-d5

Creatinine-d₅ is the deuterium labeled Creatinine. Creatinine (NSC13123) is an orally active, blood-brain barrier-permeable modulator of GABAA and NMDA receptors, with activities of antioxidation and metabolic regulation. Creatinine is generated via non-enzymatic conversion of creatine and phosphocreatine in muscle. Creatinine serum levels correlate with muscle mass, glomerular filtration rate, and extrarenal clearance, serving as an evaluation biomarker for renal function, muscle mass, and clinical outcomes, and used for perioperative renal risk assessment. In addition, Creatinine can induce specific Cryptococcus species to produce creatinine deiminase and act as their nitrogen source, while it can be secreted via renal tubules. Creatinine is widely used in research related to various diseases such as neurodegenerative diseases, psychiatric disorders, acute kidney injury, chronic kidney disease, and renal failure .

HY-Y0271S2

Urea-13C,15N2
Urea- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Urea . Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-Y0882S1

Hydroxylamine-d3 hydrochloride

Hydroxylamine-d₃ (hydrochloride) is the deuterium labeled Hydroxyamine hydrochloride. Hydroxylamine hydrochloride is a selective Monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine hydrochloride is an intermediate of nitrogen cycle in aerobic ammonium oxidizers microorganisms, such as ammonium oxidizing bacteria (AOB), ammonium oxidizing archaea (AOA) and complete ammonium oxidizing bacteria (comammox). Hydroxylamine hydrochloride impacts NO and N₂O emissions by aerobic ammonium oxidizers microorganisms and inhibits nitrite oxidizing bacteria (NOB) activity .

HY-Y0271S1

Urea-d4
Urea-d₄ is the deuterium labeled Urea . Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-W017018S2

L-Ornithine-1,2,3,4,5-13C5 hydrochloride
L-Ornithine-1,2,3,4,5- ¹³C₅ (hydrochloride) is the ¹³C-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-W013636S1

2-Ketoglutaric acid-d4

2-Ketoglutaric acid-d₄ (Alpha-Ketoglutaric acid-d₄) is the deuterium labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid Sodium is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-B0504S1

Creatinine-13C

Creatinine- ¹³C is the ¹³C-labeled Creatinine. Creatinine (NSC13123) is an orally active, blood-brain barrier-permeable modulator of GABAA and NMDA receptors, with activities of antioxidation and metabolic regulation. Creatinine is generated via non-enzymatic conversion of creatine and phosphocreatine in muscle. Creatinine serum levels correlate with muscle mass, glomerular filtration rate, and extrarenal clearance, serving as an evaluation biomarker for renal function, muscle mass, and clinical outcomes, and used for perioperative renal risk assessment. In addition, Creatinine can induce specific Cryptococcus species to produce creatinine deiminase and act as their nitrogen source, while it can be secreted via renal tubules. Creatinine is widely used in research related to various diseases such as neurodegenerative diseases, psychiatric disorders, acute kidney injury, chronic kidney disease, and renal failure .

HY-17420S

Cyclophosphamide-d4
Cyclophosphamide-d₄ is the deuterium labeled Cyclophosphamide. Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant .

HY-W017018S

L-Ornithine-d6 hydrochloride
L-Ornithine-d₆ (hydrochloride) is the deuterium labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-W017018S4

L-Ornithine-d7 hydrochloride
L-Ornithine-d₇ (hydrochloride) is the deuterium labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-N0455AS7

L-Arginine-13C hydrochloride
L-Arginine- ¹³C (hydrochloride) is the ¹³C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-N0455AS3

L-Arginine-1-13C hydrochloride
L-Arginine-1- ¹³C (hydrochloride) is the ¹³C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-W017018S5

L-Ornithine-15N2 hydrochloride
L-Ornithine- ¹⁵N₂ (hydrochloride) is the ¹⁵N-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-W013636S2

2-Ketoglutaric acid-d6
2-Ketoglutaric acid-d₆ (Alpha-Ketoglutaric acid-d₆) is the deuterium labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636S3

2-Ketoglutaric acid-13C

2-Ketoglutaric acid- ¹³C (Alpha-Ketoglutaric acid- ¹³C) is a ¹³C labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-B1204S1

Histamine-d4

Histamine-d₄ (Ergamine-d₄) is deuterium labeled Histamine (HY-B1204). Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .

HY-N0455AS5

L-Arginine-1,2-13C2 hydrochloride
L-Arginine-1,2- ¹³C₂ (hydrochloride) is the ¹³C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-B0504S5

Creatinine-15N

Creatinine- ¹⁵N (NSC13123- ¹⁵N) is the ¹⁵N-labeled Creatinine (HY-B0504). Creatinine (NSC13123) is an orally active, blood-brain barrier-permeable modulator of GABAA and NMDA receptors, with activities of antioxidation and metabolic regulation. Creatinine is generated via non-enzymatic conversion of creatine and phosphocreatine in muscle. Creatinine serum levels correlate with muscle mass, glomerular filtration rate, and extrarenal clearance, serving as an evaluation biomarker for renal function, muscle mass, and clinical outcomes, and used for perioperative renal risk assessment. In addition, Creatinine can induce specific Cryptococcus species to produce creatinine deiminase and act as their nitrogen source, while it can be secreted via renal tubules. Creatinine is widely used in research related to various diseases such as neurodegenerative diseases, psychiatric disorders, acute kidney injury, chronic kidney disease, and renal failure .

HY-W017018S3

L-Ornithine-d2 hydrochloride
L-Ornithine-d₂ (hydrochloride) is the deuterium labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-N0455AS4

L-Arginine-13C6,15N4,d7 hydrochloride
L-Arginine- ¹³C₆, ¹⁵N₄,d₇ (hydrochloride) is the deuterium, ¹³C-, and 15-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-W013636S4

2-Ketoglutaric acid-13C2

2-Ketoglutaric acid- ¹³C₂ (Alpha-Ketoglutaric acid- ¹³C₂) is a ¹³C labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-B1204S2

Histamine-13C5, 15N3

Histamine- ¹³C₅, ¹⁵N₃ (Ergamine- ¹³C₅, ¹⁵N₃) is the ¹³C and ¹⁵N labeled isotope of Histamine (HY-B1204). Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .

HY-17420S1

Cyclophosphamide-d8
Cyclophosphamide-d₈ is deuterium labeled Cyclophosphamide. Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant.

HY-W779244

1H-Pyrazole-3,4,5-d3
1H-Pyrazole-3,4,5-d₃ is the deuterium labeled 1H-pyrazole (HY-76228). 1H-pyrazole is a nitrogen-containing heterocyclic compound composed of a five-membered ring and two nitrogen atoms. 1H-pyrazole is an intermediate in organic synthesis. 1H-pyrazole coordinates with metal ions. 1H-pyrazole derivatives have antibacterial, anti-inflammatory, anti-malarial, and anti-leishmanial activities .

HY-N0455AS

L-Arginine-15N2 hydrochloride 1 Publications Verification
L-Arginine- ¹⁵N₂ (hydrochloride) is the ¹⁵N-labeled L-Arginine (hydrochloride). L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-177079S

Dazodeunetant
Dazodeunetant (Example 56) is a nitrogen-containing fused ring derivative. Dazodeunetant is an inhibitor of neurokinin (NK). Dazodeunetant has an IC₅₀ 0f 75.99 nM against NK3R in HEK293-NK3 (IP1). Dazodeunetant can be studied in research for menopausal hot flashes .

HY-Y0496S

1,4-Dichlorobenzene-d4

1,4-Dichlorobenzene-d₄ is the deuterium labeled 1,4-Dichlorobenzene. 1,4-Dichlorobenzene is a non-genotoxic, orally active mitogenic/tumor-promoting carcinogen that is also widely used as a dye, resin intermediate, and deodorant, moth repellent/insecticide. 1,4-Dichlorobenzene induces liver tumors in mice and promotes the growth of spontaneous precancerous lesions, but shows no liver tumor-inducing activity in F344 rats. 1,4-Dichlorobenzene increases the levels of white blood cell count, serum alanine aminotransferase and blood urea nitrogen in occupationally exposed populations. 1,4-Dichlorobenzene is metabolized to 2,5-dichlorophenol and excreted in urine, and this metabolite can serve as a biomarker for 1,4-Dichlorobenzene exposure. Due to its specific hepatotoxic characteristics, 1,4-Dichlorobenzene is applicable to liver cancer-related research .

HY-B1204S4

Histamine-15N3

Histamine- ¹⁵N₃ is the ¹⁵N₃-labeled Histamine (HY-B1204). Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .

HY-160471S

N-Nitrososertraline-d3
N-Nitrososertraline-d3 is a Sertraline isotope labeled with deuterium and nitrogen-15. N-Nitrososertraline-d3 can be used to track the metabolism and pharmacokinetics of Sertraline in vivo.

HY-B0515AS1

Ibandronic acid-d3
Ibandronic acid-d₃ is the deuterium labeled Ibandronic acid. Ibandronic acid is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.

HY-B0515AS

Ibandronic Acid-d3 sodium salt
Ibandronic Acid-d₃ (sodium) is the deuterium labeled Ibandronic acid. Ibandronic acid is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis[1][2].

HY-17420AS

Cyclophosphamide-d8 hydrate
Cyclophosphamide-d₈ (hydrate) is the deuterium labeled Cyclophosphamide hydrate. Cyclophosphamide hydrate is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities .

HY-W017018S1

L-Ornithine-1,2-13C2 hydrochloride
L-Ornithine-1,2- ¹³C₂ (hydrochloride) is the ¹³C-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-108685S

Alendronate-d4 sodium
Alendronate-d₄ (sodium) (Alendronic acid-d₄ (monosodium salt)) is deuterium labeled Alendronate sodium. Alendronate sodium is an orally active nitrogen-containing bisphosphonate. Alendronate sodium potently inhibits bone resorption. Alendronate sodium is used for the research of postmenopausal osteoporosis .

HY-N0455AS9

L-Arginine-15N4,d7 hydrochloride
L-Arginine- ¹⁵N₄,d₇ (hydrochloride) is the deuterium and ¹⁵N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-13593S

Chlorambucil-d8
Chlorambucil-d₈ is the deuterium labeled Chlorambucil. Chlorambucil (CB-1348), an orally active antineoplastic agent, is a bifunctional alkylating agent belonging to the nitrogen mustard group. Chlorambucil can be used for the research of lymphocytic leukemia, ovarian and breast carcinomas, and Hodgkin’s disease .

HY-13593S1

Chlorambucil-d8-1
Chlorambucil-d₈-1 is the deuterium labeled Chlorambucil. Chlorambucil (CB-1348), an orally active antineoplastic agent, is a bifunctional alkylating agent belonging to the nitrogen mustard group. Chlorambucil can be used for the research of lymphocytic leukemia, ovarian and breast carcinomas, and Hodgkin’s disease .

HY-W725504

2-Hydroxy-3-methylbutanoic acid-d7

2-Hydroxy-3-methylbutanoic acid-d₇ is the deuterium labeled 2-Hydroxy-3-methylbutanoic acid (HY-W008150). 2-Hydroxy-3-methylbutanoic acid is an α-hydroxy analogue of valine and a valine precursor that reduces urea excretion. 2-Hydroxy-3-methylbutanoic acid can promote the growth of chickens and rats, and is converted into valine in the body, participating in protein synthesis and maintaining nitrogen balance, thereby supporting animal growth and development. 2-Hydroxy-3-methylbutanoic acid has a more significant effect on the valine-deficient dietary model. 2-Hydroxy-3-methylbutanoic acid is mainly used in animal nutrition research to evaluate its potential application as a nitrogen source substitute in feed .

HY-B0817S

Pyridaben-d13

Pyridaben-d₁₃ is the deuterium labeled Pyridaben . Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC₅₀ value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function .

HY-N0455AS11

L-Arginine-13C6,d14 hydrochloride
L-Arginine-13C6,d14 hydrochloride ((S)-(+)-Arginine-13C6,d14 hydrochloride) is a deuterated derivative of L-Arginine hydrochloride (HY-N0455A) that is labeled with ¹³C6. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) serves as a nitrogen donor for the synthesis of nitric oxide and is a vasodilator .

HY-Y0271S3

Urea-13C,15N

Urea- ¹³C, ¹⁵N is the ¹³C- and ¹⁵N-labeled Urea (HY-Y0271). Urea is a powerful protein denaturant via both direct and indirect mechanisms. A potent emollient and keratolytic agent. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry .

HY-Y0882S

Hydroxylamine-15N hydrochloride

Hydroxylamine- ¹⁵N hydrochloride is the ¹⁵N-labeled Hydroxylamine hydrochloride (HY-Y0882). Hydroxylamine hydrochloride is a selective Monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine hydrochloride is an intermediate of nitrogen cycle in aerobic ammonium oxidizers microorganisms, such as ammonium oxidizing bacteria (AOB), ammonium oxidizing archaea (AOA) and complete ammonium oxidizing bacteria (comammox). Hydroxylamine hydrochloride impacts NO and N2O emissions by aerobic ammonium oxidizers microorganisms and inhibits nitrite oxidizing bacteria (NOB) activity .

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W013636AG

2-Ketoglutaric acid Sodium Alpha-Ketoglutaric acid Sodium	Tyrosinase Endogenous Metabolite	Neurological Disease Metabolic Disease
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) Sodium (GMP) is 2-Ketoglutaric acid Sodium (HY-W013636A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. 2-Ketoglutaric acid Sodium is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

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