90 Results for "

nucleobase

" in MedChemExpress (MCE) Product Catalog:
Products (90)

90 Results for "nucleobase" in MCE Product Catalog:

24
24 Publications Verification
Cat. No.: HY-B0152
CAS No.: 73-24-5
Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .
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24
24 Publications Verification
Cat. No.: HY-B0152B
CAS No.: 321-30-2
Synonyms: 6-Aminopurine hemisulfate; Vitamin B4 hemisulfate
Adenine hemisulfate (6-Aminopurine hemisulfate), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hemisulfate acts as a chemical component of DNA and RNA. Adenine hemisulfate also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .
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24
24 Publications Verification
Cat. No.: HY-B0152A
CAS No.: 2922-28-3
Synonyms: 6-Aminopurine hydrochloride; Vitamin B4 hydrochloride
Adenine hydrochloride (6-Aminopurine hydrochloride), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hydrochloride acts as a chemical component of DNA and RNA. Adenine hydrochloride also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .
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24
24 Publications Verification
Cat. No.: HY-W015213
CAS No.: 6055-72-7
Adenine monohydrochloride hemihydrate is a hydrochloride derivative of Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .
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5
5 Cited Publications
Cat. No.: HY-I0960
CAS No.: 66-22-8
Uracil is a pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. Uracil is a frequently occurring DNA base damage that results from the spontaneous or chemically induced deamination of cytosine and is mutagenic at the level of replication. Uracil could potentially alter transcriptional fidelity, resulting in production of mutant proteins .
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2
2 Cited Publications
Cat. No.: HY-B0152S1
CAS No.: 86967-48-8
Synonyms: Adenine-8-C13; 9H-Purin-6-amine-8-13C
Adenine- 13C is the 13C labeled Adenine . Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .
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1
1 Cited Publications
Cat. No.: HY-N10574
CAS No.: 72496-59-4
Queuine is a selective substrate for tRNA guanine transglycosylase (TGT) and can be incorporated into eukaryotic tRNA. Queuine promotes tRNA modification, affecting mitochondrial function and Warburg metabolic phenotype. If Queuine is deficient, aerobic glycolysis can be enhanced, oxidative phosphorylation can be inhibited, and Warburg metabolism can be promoted, accompanied by increased ammonia and lactate production and increased lactate dehydrogenase activity. Queuine can be used for autoimmune diseases (such as experimental models of multiple sclerosis) and cancer metabolic regulation, and its deficiency is associated with low tRNA modification in tumor cells .
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1
1 Cited Publications
Cat. No.: HY-W009162
CAS No.: 63-37-6
Synonyms: 5'-Cytidylic acid; 5'-CMP
Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group .
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1
1 Cited Publications
Cat. No.: HY-112582C
CAS No.: 3056945-59-3
Purity:  99.70%
Synonyms: 1-Methylpseudouridine-5′-triphosphate trisodium; N1-Me-Pseudo UTP trisodium; N1-Methyl-Pseudo-UTP trisodium
N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is a nucleobase-modified nucleotide. N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is used for synthesizing mRNA with reduced immunogenicity and improved stability .
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1
1 Cited Publications
Cat. No.: HY-112582A
CAS No.: 1428903-59-6
Synonyms: 1-Methylpseudouridine-5′-triphosphate
N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability.
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1
1 Cited Publications
Cat. No.: HY-41461
CAS No.: 360-97-4
Synonyms: 5-Aminoimidazole-4-carboxamide; AICA
5-Amino-3H-imidazole-4-Carboxamide (5-Aminoimidazole-4-carboxamide; AICA) is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular .
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1
1 Cited Publications
Cat. No.: HY-W013159
CAS No.: 33430-61-4
Synonyms: 5′-dGMP disodium
2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .
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1
1 Cited Publications
Cat. No.: HY-41461A
CAS No.: 72-40-2
Synonyms: 5-Aminoimidazole-4-carboxamide hydrochloride; AICA hydrochloride
Category:  

Microorganisms

Target:  

Endogenous Metabolite

5-Amino-3H-imidazole-4-Carboxamide (AICA) hydrochloride is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular .
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1
1 Cited Publications
Cat. No.: HY-N10574A
CAS No.: 86496-18-6
Target:  

Others

Queuine dihydrochloride is a selective substrate for tRNA guanine transglycosylase (TGT) and can be incorporated into eukaryotic tRNA. Queuine dihydrochloride promotes tRNA modification, affecting mitochondrial function and Warburg metabolic phenotype. If Queuine dihydrochloride is deficient, aerobic glycolysis can be enhanced, oxidative phosphorylation can be inhibited, and Warburg metabolism can be promoted, accompanied by increased ammonia and lactate production and increased lactate dehydrogenase activity. Queuine dihydrochloride can be used for autoimmune diseases (such as experimental models of multiple sclerosis) and cancer metabolic regulation, and its deficiency is associated with low tRNA modification in tumor cells .
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1
1 Cited Publications
Cat. No.: HY-I0960S4
CAS No.: 24897-52-7
Uracil-d2 is the deuterium labeled Uracil . Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA .
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Cat. No.: HY-115642
CAS No.: 86694-45-3
Purity:  98.88%
Research Areas:  

Metabolic Disease

preQ1 dihydrochloride is a modified, guanine-derived nucleobase and a precursor of Queuine (HY-N10574) biosynthesis. preQ1 dihydrochloride binds to the aptamer of PreQ1 riboswitch with high affinity .
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Cat. No.: HY-W006395
CAS No.: 1122-47-0
Research Areas:  

Cancer

1-Methylcytosine is a pyrimidinone that serves as a nucleobase for hachimoji DNA and pairs with isoguanine . 1-Methylcytosine exerts weak antiproliferative activity against cervical cancer cells. 1-Methylcytosine can be used in the research of cervical cancer .
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Cat. No.: HY-W019815
CAS No.: 759-73-9
Synonyms: ENU; N-Nitroso-N-ethylurea
Target:  

DNA/RNA Synthesis

Research Areas:  

Neurological Disease Cancer

N-Ethyl-N-nitrosourea (ENU) is a DNA alkylating agent. N-Ethyl-N-nitrosourea induces leukemia by alkylating nucleobases, disrupting DNA, and resulting in bone marrow suppression and the formation of leukemic cells. N-Ethyl-N-nitrosourea is teratogenic in vivo, inducing tumor formation and paw malformations in pregnant rats. N-Ethyl-N-nitrosourea cause central nervous system (CNS) tumors and genetic disorders .
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Cat. No.: HY-W002272
CAS No.: 108-53-2
Isocytosine is a non-natural nucleobase and an isomer of cytosine. It is used in combination with Isoguanine in studies of unnatural nucleic acid analogues of the normal base pairs in DNA and used as a nucleobase of hachimoji RNA .
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Cat. No.: HY-69014
CAS No.: 3289-47-2
2-O-Methylcytosine, an O-alkylated analogue a DNA adduct, is the damaged nucleobase .
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