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nucleobase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Bacterial (3) Biochemical Assay Reagents (3) CHIKV (1) Cyclic GMP-AMP Synthase (1) Dengue Virus (1) DNA Alkylator/Crosslinker (1) DNA/RNA Synthesis (30) Drug Derivative (1) Drug Intermediate (2) Endogenous Metabolite (53) Flavivirus (1) Fungal (2) Influenza Virus (2) Isotope-Labeled Compounds (17) Nucleoside Antimetabolite/Analog (17) Parasite (2) Phosphoramidites (1) Phosphorylase (1) Reference Standards (13) SARS-CoV (1) STING (1)
By Research Areas:	Cancer (44) Cardiovascular Disease (2) Infection (8) Inflammation/Immunology (1) Metabolic Disease (23) Neurological Disease (1)
Oligonucleotides:	Inosine Nucleoside (1) Nucleotide Analogs (5) Freeze-drying Protective Agents (1) Uracil (1) Phosphoramidites (1)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Natural
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Recombinant Proteins

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0152

Adenine Maximum Cited Publications 22 Publications Verification	DNA/RNA Synthesis Endogenous Metabolite	Infection Cancer
Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-N10574

Queuine 1 Publications Verification	Bacterial	Metabolic Disease Cancer
Queuine is a selective substrate for tRNA guanine transglycosylase (TGT) and can be incorporated into eukaryotic tRNA. Queuine promotes tRNA modification, affecting mitochondrial function and Warburg metabolic phenotype. If Queuine is deficient, aerobic glycolysis can be enhanced, oxidative phosphorylation can be inhibited, and Warburg metabolism can be promoted, accompanied by increased ammonia and lactate production and increased lactate dehydrogenase activity. Queuine can be used for autoimmune diseases (such as experimental models of multiple sclerosis) and cancer metabolic regulation, and its deficiency is associated with low tRNA modification in tumor cells .

HY-W009162

Cytidine 5'-monophosphate 1 Publications Verification 5'-Cytidylic acid; 5'-CMP	Endogenous Metabolite	Metabolic Disease
Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group .

HY-I0960

Uracil 4 Publications Verification	Endogenous Metabolite Drug Derivative	Infection Cancer
Uracil is a pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. Uracil is a frequently occurring DNA base damage that results from the spontaneous or chemically induced deamination of cytosine and is mutagenic at the level of replication. Uracil could potentially alter transcriptional fidelity, resulting in production of mutant proteins .

HY-112582C

N1-Methylpseudouridine-5′-triphosphate trisodium solution (100 mM) 1 Publications Verification 1-Methylpseudouridine-5′-triphosphate trisodium; N1-Me-Pseudo UTP trisodium; N1-Methyl-Pseudo-UTP trisodium	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis	Cardiovascular Disease
N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is a nucleobase-modified nucleotide. N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is used for synthesizing mRNA with reduced immunogenicity and improved stability .

HY-B0152B

Adenine hemisulfate Maximum Cited Publications 22 Publications Verification 6-Aminopurine hemisulfate; Vitamin B4 hemisulfate	DNA/RNA Synthesis Endogenous Metabolite	Cancer
Adenine hemisulfate (6-Aminopurine hemisulfate), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hemisulfate acts as a chemical component of DNA and RNA. Adenine hemisulfate also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-112582A

N1-Methylpseudouridine-5′-triphosphate solution (100 mM) 1 Publications Verification 1-Methylpseudouridine-5′-triphosphate	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis	Cardiovascular Disease Others
N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability.

HY-B0152S1

Adenine-13C 2 Publications Verification Adenine-8-C13; 9H-Purin-6-amine-8-¹³C	DNA/RNA Synthesis Endogenous Metabolite	Cancer
Adenine- ¹³C is the ¹³C labeled Adenine . Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-41461

5-Amino-3H-imidazole-4-Carboxamide 1 Publications Verification 5-Aminoimidazole-4-carboxamide; AICA	Endogenous Metabolite	Others
5-Amino-3H-imidazole-4-Carboxamide (5-Aminoimidazole-4-carboxamide; AICA) is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular .

HY-W013159

2'-Deoxyguanosine 5'-monophosphate disodium 1 Publications Verification 5′-dGMP disodium	Endogenous Metabolite Nucleoside Antimetabolite/Analog	Metabolic Disease
2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .

HY-B0152A

Adenine hydrochloride Maximum Cited Publications 22 Publications Verification 6-Aminopurine hydrochloride; Vitamin B4 hydrochloride	DNA/RNA Synthesis Endogenous Metabolite	Cancer
Adenine hydrochloride (6-Aminopurine hydrochloride), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hydrochloride acts as a chemical component of DNA and RNA. Adenine hydrochloride also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-115642

preQ1 dihydrochloride	Nucleoside Antimetabolite/Analog	Metabolic Disease
preQ1 dihydrochloride is a modified, guanine-derived nucleobase and a precursor of Queuine (HY-N10574) biosynthesis. preQ1 dihydrochloride binds to the aptamer of PreQ1 riboswitch with high affinity .

HY-W006395

1-Methylcytosine	Nucleoside Antimetabolite/Analog	Cancer
1-Methylcytosine is a pyrimidinone that serves as a nucleobase for hachimoji DNA and pairs with isoguanine . 1-Methylcytosine exerts weak antiproliferative activity against cervical cancer cells. 1-Methylcytosine can be used in the research of cervical cancer .

HY-W019815

N-Ethyl-N-nitrosourea ENU; N-Nitroso-N-ethylurea	DNA/RNA Synthesis	Neurological Disease Cancer
N-Ethyl-N-nitrosourea (ENU) is a DNA alkylating agent. N-Ethyl-N-nitrosourea induces leukemia by alkylating nucleobases, disrupting DNA, and resulting in bone marrow suppression and the formation of leukemic cells. N-Ethyl-N-nitrosourea is teratogenic in vivo, inducing tumor formation and paw malformations in pregnant rats. N-Ethyl-N-nitrosourea cause central nervous system (CNS) tumors and genetic disorders .

HY-W002272

Isocytosine	Nucleoside Antimetabolite/Analog	Others
Isocytosine is a non-natural nucleobase and an isomer of cytosine. It is used in combination with Isoguanine in studies of unnatural nucleic acid analogues of the normal base pairs in DNA and used as a nucleobase of hachimoji RNA .

HY-69014

2-O-Methylcytosine	DNA/RNA Synthesis Endogenous Metabolite	Cancer
2-O-Methylcytosine, an O-alkylated analogue a DNA adduct, is the damaged nucleobase .

HY-130802

5-Aminouridine	Fungal Influenza Virus	Infection Cancer
5-Aminouridine can modify nucleobases and can be incorporated into the target DNA. 5-Aminouridine exhibits a wide range of biological activity and it inhibits the growth of tumors, fungi and viruses .

HY-41461A

5-Amino-3H-imidazole-4-carboxamide hydrochloride 1 Publications Verification 5-Aminoimidazole-4-carboxamide hydrochloride; AICA hydrochloride	Endogenous Metabolite	Others
5-Amino-3H-imidazole-4-Carboxamide (AICA) hydrochloride is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular .

HY-50071

6-Amino-5-nitropyridin-2-one	Nucleoside Antimetabolite/Analog	Others
6-Amino-5-nitropyridin-2-one is a pyridine base and used as a nucleobase of hachimoji DNA, in which it pairs with 5-aza-7-deazaguanine .

HY-N10574A

Queuine dihydrochloride 1 Publications Verification	Others	Metabolic Disease Cancer
Queuine dihydrochloride is a selective substrate for tRNA guanine transglycosylase (TGT) and can be incorporated into eukaryotic tRNA. Queuine dihydrochloride promotes tRNA modification, affecting mitochondrial function and Warburg metabolic phenotype. If Queuine dihydrochloride is deficient, aerobic glycolysis can be enhanced, oxidative phosphorylation can be inhibited, and Warburg metabolism can be promoted, accompanied by increased ammonia and lactate production and increased lactate dehydrogenase activity. Queuine dihydrochloride can be used for autoimmune diseases (such as experimental models of multiple sclerosis) and cancer metabolic regulation, and its deficiency is associated with low tRNA modification in tumor cells .

HY-111531

DMTr-LNA-5MeU-3-CED-phosphoramidite	Phosphoramidites Nucleoside Antimetabolite/Analog DNA/RNA Synthesis	Others
DMTr-LNA-5MeU-3-CED-phosphoramidite is a Phosphoramidite derivative and Nucleoside derivative .

HY-117813

2-Thiouridine	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Dengue Virus Flavivirus CHIKV SARS-CoV	Infection
2-Thiouridine is an orally active modified nucleobase. 2-Thiouridine stabilizes U:A base pairs and destabilizes U:G wobble base pairs. 2-Thiouridine significantly improves the efficiency and accuracy of nonenzymatic replication of mixed-sequence A/U-containing RNA templates. 2-Thiouridine exhibits antiviral activity against multiple positive-sense single-stranded RNA viruses (DENV2, ZIKV, YFV, JEV, WNV, CHIKV, human coronaviruses ( [HCoV]-229E, HCoV-OC43, SARS-CoV), and MERS-CoV) .

HY-B0152S4

Adenine-15N5 6-Aminopurine-¹⁵N₅; Vitamin B4-¹⁵N₅	Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite	Cancer
Adenine- ¹⁵N₅ (6-Aminopurine- ¹⁵N₅; Vitamin B4- ¹⁵N₅) is ¹⁵N labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.

HY-E70042

Nucleoside hydrolase (IAGNH)	Endogenous Metabolite	Metabolic Disease
Nucleoside hydrolase (IAGNH) is a glycosidase. Nucleoside hydrolase (IAGNH) catalyzes the cleavage of the N-glycosidic bond in nucleosides to enable the recycling of the nucleobases and Rib .

HY-I0960S4

Uracil-d2	Endogenous Metabolite	Cancer
Uracil-d₂ is the deuterium labeled Uracil . Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA .

HY-W010450R

Thymine (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease Cancer
Thymine (Standard) is the analytical standard of Thymine. This product is intended for research and analytical applications. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM.

HY-B0152S

Adenine-d1 6-Aminopurine-d₁; Vitamin B4-d₁	DNA/RNA Synthesis Endogenous Metabolite	Cancer
Adenine-d is the deuterium labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-B0152R

Adenine (Standard)	Reference Standards DNA/RNA Synthesis Endogenous Metabolite	Cancer
Adenine (Standard) is the analytical standard of Adenine. This product is intended for research and analytical applications. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-D2353

Biotin-PEG3-benzophenone	DNA/RNA Synthesis	Cancer
Biotin-PEG3-benzophenone is biotin-labeled Benzophenone (HY-Y0546). Benzophenone is an endogenous metabolite and a photosensitizer that has been implicated in photosensitive damage to DNA. Benzophenone causes nucleobase oxidation, formation of cyclobutane-pyrimidine dimers, single-strand breaks, DNA-protein cross-links or abasic sites, different pathologies that may occur in nucleosides, oligonucleotides or DNA .

HY-W009162S5

Cytidine 5′-monophosphate-13C9,15N3 dilithium 5'-Cytidylic acid-13C9,15N3 dilithium; 5'-CMP-13C9,15N3 dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Cytidine 5′-monophosphate- ¹³C₉, ¹⁵N₃ (5'-Cytidylic acid- ¹³C₉, ¹⁵N₃ dilithium; 5'-CMP- ¹³C₉, ¹⁵N₃) dilithium is ¹³C and ¹⁵N-labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.

HY-W010918R

Adenosine 5'-diphosphate (Standard) Adenosine diphosphate (Standard); ADP (Standard)	Reference Standards Endogenous Metabolite	Others
Adenosine 5'-diphosphate (Standard) is the analytical standard of Adenosine 5'-diphosphate. This product is intended for research and analytical applications. Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors. In Vitro: Adenosine 5'-diphosphate consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases. ATP is an important energy transfer molecule in cells. Adenosine 5'-diphosphate is utilized in a wide number of cellular processes, including respiration, biosynthetic reactions, motility, and cell division.

HY-B0152S3

Adenine-13C5 6-Aminopurine-¹³C₅; Vitamin B4-¹³C₅	Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite	Cancer
Adenine- ¹³C₅ (6-Aminopurine- ¹³C₅; Vitamin B4- ¹³C₅) is ¹³C-labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.

HY-I0960R

Uracil (Standard)	Reference Standards Endogenous Metabolite	Cancer
Uracil (Standard) is the analytical standard of Uracil. This product is intended for research and analytical applications. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA.

HY-I0960S1

Uracil-13C4	Endogenous Metabolite	Cancer
Uracil- ¹³C₄ is the ¹³C labeled Uracil . Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA .

HY-I0960S9

Uracil-d4	Endogenous Metabolite	Cancer
Uracil-d₄ is the deuterium labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].

HY-W015213

Adenine monohydrochloride hemihydrate Maximum Cited Publications 22 Publications Verification	Endogenous Metabolite DNA/RNA Synthesis	Metabolic Disease
Adenine monohydrochloride hemihydrate is a hydrochloride derivative of Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-136559

6-Azathymine	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Bacterial Influenza Virus	Infection
6-Azathymine, a 6-nitrogen analog of thymine, is a potent D-3-aminoisobutyrate-pyruvate aminotransferase inhibitor. 6-Azathymine inhibits the biosynthesis of DNA, and has antibacterial and antiviral activities .

HY-N15159

Cladophorol A	Cyclic GMP-AMP Synthase STING Parasite	Infection Inflammation/Immunology
Cladophorol A is a cyclic GMP-AMP synthase (cGAS) inhibitor. Cladophorol A binds to the conserved adenosine nucleobase binding site within the cGAS active site to inhibit its catalytic activity. Cladophorol A effectively inhibits the overactivation of the cGAS-STING pathway with an IC₅₀ of 370 nM. Cladophorol A inhibits asexual blood-stage Plasmodium falciparum with an EC₅₀ of 0.7 μg/mL. Cladophorol A can be used for the researches of inflammatory disease and malaria .

HY-B0152S7

Adenine-15N5 hydrochloride hydrate 6-Aminopurine-¹⁵N₅ hydrochloride hydrate; Vitamin B4-¹⁵N₅ hydrochloride hydrate	Isotope-Labeled Compounds DNA/RNA Synthesis	Cancer
Adenine- ¹⁵N₅ (6-Aminopurine- ¹⁵N₅) hydrochloride hydrate is the ¹⁵N-labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-W749117

Inosine 5′-diphosphate sodium	Endogenous Metabolite	Metabolic Disease
Inosine 5’-diphosphate sodium is a purine ribonucleoside 5’-diphosphate with inosine as the nucleobase, which can participate in intracellular energy metabolism and signal transduction processes .

HY-I0960S5

Uracil-15N2	Endogenous Metabolite	Cancer
Uracil- ¹⁵N₂ is the ¹⁵N labeled Uracil . Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA .

HY-I0960S6

Uracil-d2-1	Endogenous Metabolite	Cancer
Uracil-d₂-1 is the deuterium labeled Uracil . Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA .

HY-I0960S3

Uracil-13C4,15N2	Endogenous Metabolite	Cancer
Uracil- ¹³C₄, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Uracil . Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA .

HY-W010450S4

Thymine-d4-1	Endogenous Metabolite	Cancer
Thymine-d₄-1 is the deuterium labeled Thymine . Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM .

HY-W747214

Thymine-15N2,13C	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
Thymine- ¹⁵N₂, ¹³C is the ¹³C and ¹⁵N labeled Thymine (HY-W010450). Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-Fluorouracil (HY-90006) in cancer treatment, with a K_m of 2.3 μM .

HY-W009162R

Cytidine 5'-monophosphate (Standard) 5'-Cytidylic acid (Standard); 5'-CMP (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Cytidine 5'-monophosphate (Standard) is the analytical standard of Cytidine 5'-monophosphate. This product is intended for research and analytical applications. Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group .

HY-W013159S

2'-Deoxyguanosine 5'-monophosphate-13C10,15N5 disodium 5′-dGMP-13C10,15N5 disodium	Isotope-Labeled Compounds Endogenous Metabolite Nucleoside Antimetabolite/Analog	Metabolic Disease
2'-Deoxyguanosine 5'-monophosphate- ¹³C₁₀, ¹⁵N₅ (dGMP- ¹³C₁₀, ¹⁵N₅) disodium is the ¹³C and ¹⁵N labeled 2'-Deoxyguanosine 5'-monophosphate disodium (HY-W013159). 2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .

HY-B0152BR

Adenine hemisulfate (Standard) 6-Aminopurine hemisulfate (Standard); Vitamin B4 hemisulfate (Standard)	DNA/RNA Synthesis Endogenous Metabolite Reference Standards	Cancer
Adenine (hemisulfate) (Standard) is the analytical standard of Adenine (hemisulfate). This product is intended for research and analytical applications. Adenine hemisulfate (6-Aminopurine hemisulfate), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hemisulfate acts as a chemical component of DNA and RNA. Adenine hemisulfate also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-126060

9-Ethylguanine	Nucleoside Antimetabolite/Analog	Cancer
9-Ethylguanine is a modified nucleobase derived from guanine that coordinates to azolato-bridged dinuclear platinum(II) complexes via its N7 nitrogen atom. 9-Ethylguanine forms adducts with a ruthenium(II) complex via the N7 position of its guanine moiety .

HY-I0960S

Uracil-13C2,15N2	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
Uracil- ¹³C₂, ¹⁵N₂ is the ¹³C-labeled and ¹⁵N-labeled Uracil. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA.

Cat. No.	Product Name

HY-L0116V

Asinex Macrocycles for RNA Library

1,065 compounds

Macrocycles are promising scaffolds for the design of novel RNA targeting molecules. This collection of macrocycles for RNA consists of very diverse, drug-like molecules which incorporate certain known RNA-recognition elements (e.g. nucleobase ring systems and analogs) distributed within macrocyclic rings or peripheral fragments. As macrocyclic molecules tend to be larger than traditional screening molecules, it is vital to carefully assess and control their physicochemical properties. All macrocycles have been tested for aqueous and DMSO solubility with cutoffs applied at 10 mM in DMSO and 50 µM in PBS (pH 7.4); PAMPA permeability has also been tested for representative set of macrocycles.

HY-L907

MCE Kinase Hinge Binder Fragment Library

12,412 compounds

The most prominent mechanism of action of kinase inhibitors is their competition with ATP by binding to the hinge region of the kinase protein. Once the kinase is blocked by an inhibitor, it loses the ability to transfer phosphate groups from ATP to other molecules, resulting in the loss of kinase activity.

The hinge-binding region of kinase inhibitors mimics the interaction pattern between the ATP nucleobase and the kinase. MCE extracted thousands of kinase inhibitors from the ChEMBL database and isolated their molecular fragments. In certain cases, the amino and amide groups on the molecular fragments are crucial for binding in the hinge region. Therefore, we enhanced the diversity of the collected results by adding these two groups to unoccupied positions on the ring system. Subsequently, the fragments were assessed for their hinge region binding ability via docking at distinct kinases, we also applied pharmacophore constraints to ensure interactions with key amino acids in the kinase hinge region, ultimately obtaining kinase-related molecular fragments.

MCE provides over 12,412 kinase fragment molecules that meet the above requirements and are available off the shelf, serving as an effective tool for screening and developing drugs targeting kinases.

Cat. No.	Product Name	Type

HY-D2353

Biotin-PEG3-benzophenone

Fluorescent Dyes

Biotin-PEG3-benzophenone is biotin-labeled Benzophenone (HY-Y0546). Benzophenone is an endogenous metabolite and a photosensitizer that has been implicated in photosensitive damage to DNA. Benzophenone causes nucleobase oxidation, formation of cyclobutane-pyrimidine dimers, single-strand breaks, DNA-protein cross-links or abasic sites, different pathologies that may occur in nucleosides, oligonucleotides or DNA .

Cat. No.	Product Name	Type

HY-112582C

N1-Methylpseudouridine-5′-triphosphate trisodium solution (100 mM) 1 Publications Verification 1-Methylpseudouridine-5′-triphosphate trisodium; N1-Me-Pseudo UTP trisodium; N1-Methyl-Pseudo-UTP trisodium	Biochemical Assay Reagents
N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is a nucleobase-modified nucleotide. N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is used for synthesizing mRNA with reduced immunogenicity and improved stability .

HY-112582A

N1-Methylpseudouridine-5′-triphosphate solution (100 mM) 1 Publications Verification 1-Methylpseudouridine-5′-triphosphate	Biochemical Assay Reagents
N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability.

HY-41461A

5-Amino-3H-imidazole-4-carboxamide hydrochloride 1 Publications Verification 5-Aminoimidazole-4-carboxamide hydrochloride; AICA hydrochloride	Biochemical Assay Reagents
5-Amino-3H-imidazole-4-Carboxamide (AICA) hydrochloride is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular .

HY-117813

2-Thiouridine

Biochemical Assay Reagents

2-Thiouridine is an orally active modified nucleobase. 2-Thiouridine stabilizes U:A base pairs and destabilizes U:G wobble base pairs. 2-Thiouridine significantly improves the efficiency and accuracy of nonenzymatic replication of mixed-sequence A/U-containing RNA templates. 2-Thiouridine exhibits antiviral activity against multiple positive-sense single-stranded RNA viruses (DENV2, ZIKV, YFV, JEV, WNV, CHIKV, human coronaviruses ( [HCoV]-229E, HCoV-OC43, SARS-CoV), and MERS-CoV) .

HY-41461AR

5-Amino-3H-imidazole-4-carboxamide hydrochloride (Standard)

5-Aminoimidazole-4-carboxamide hydrochloride (Standard); AICA hydrochloride (Standard)

Biochemical Assay Reagents

5-Amino-3H-imidazole-4-carboxamide (hydrochloride) (Standard) is the analytical standard of 5-Amino-3H-imidazole-4-carboxamide hydrochloride (HY-41461A). This product is intended for research and analytical applications. 5-Amino-3H-imidazole-4-Carboxamide (AICA) hydrochloride is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular .

Cat. No.	Product Name	Target	Research Area

HY-P11690

Fmoc-Aeg-OBn	Biochemical Assay Reagents	Cancer
Fmoc-Aeg-OBn is a benzyl-protected N-(2-aminoethyl)-glycine PNA backbone derivative. Fmoc-Aeg-OBn serves as a key intermediate for the synthesis of Fmoc-protected PNA monomers with modified nucleobases. Fmoc-Aeg-OBn can be used to prepare PNA with unique physicochemical properties, which is suitable for antisense and gene diagnostic applications. Fmoc-Aeg-OBn is applicable to cancer-related research .

HY-W025936

Fmoc-PNA-G(Bhoc)-OH	Drug Intermediate	Others
Fmoc‑PNA‑G (Bhoc)‑OH is a guanine-containing peptide nucleic acid monomer, in which both Bhoc on the nucleobase and Fmoc on the backbone serve as protecting groups. Fmoc‑PNA‑G (Bhoc)‑OH is applicable for the synthesis of peptide nucleic acids .

HY-403689

Fmoc-PNA-J(Boc)-OH	Biochemical Assay Reagents	Others
Fmoc-PNA-J(Boc)-OH is a nucleobase-modified PNA monomer (2-aminopyridine PNA monomer M) with Fmoc and Boc protecting groups, used for solid-phase synthesis of PNAs that form stable Hoogsteen triple helices with double-stranded RNA at physiologically relevant conditions .

HY-P11685

Fmoc-PNA-thioU(PMB)-OH	DNA/RNA Synthesis	Others
Fmoc-PNA-thioU(PMB)-OH is a nucleobase-modified peptide nucleic acid (PNA) monomer used in solid-phase synthesis. Fmoc-PNA-thioU(PMB)-OH features a thiouracil base protected with a p-methoxybenzyl (PMB) group on an Fmoc-protected backbone, designed for incorporating modified PNA bases into oligonucleotides to study binding properties.

HY-W574398

Fmoc-Aeg-OH	Biochemical Assay Reagents	Others
Fmoc-Aeg-OH is a peptide nucleic acid (PNA) backbone intermediate and an Fmoc-protected carboxylic acid. Fmoc-Aeg-OH can be coupled with base acetic acids to synthesize Fmoc-protected PNA monomers, including those with modified bases .

HY-P11683

Boc-PNA-D(tetraZ)-OH	DNA/RNA Synthesis	Others
Boc-PNA-D(tetraZ)-OH is a specialized Peptide Nucleic Acid (PNA) monomer used in solid-phase peptide synthesis, featuring a N-tert-butoxycarbonyl (Boc) protected backbone and a 2,6-diaminopurine nucleobase. Boc-PNA-D(tetraZ)-OH helps increase PNA solubility and binding affinity, often used in molecular diagnostics.

HY-W784623

Boc-PNA-A(Z)-OH	Drug Intermediate	Others
Boc-PNA-A(Z)-OH is a Boc-protected peptide nucleic acid monomer with a benzyloxycarbonyl protecting group on the adenine base .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0152

Adenine Maximum Cited Publications 22 Publications Verification	Structural Classification Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification Cancer	DNA/RNA Synthesis Endogenous Metabolite
Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-N10574

Queuine 1 Publications Verification	Alkaloids Microorganisms Pyrrole Alkaloids Source Classification	Bacterial
Queuine is a selective substrate for tRNA guanine transglycosylase (TGT) and can be incorporated into eukaryotic tRNA. Queuine promotes tRNA modification, affecting mitochondrial function and Warburg metabolic phenotype. If Queuine is deficient, aerobic glycolysis can be enhanced, oxidative phosphorylation can be inhibited, and Warburg metabolism can be promoted, accompanied by increased ammonia and lactate production and increased lactate dehydrogenase activity. Queuine can be used for autoimmune diseases (such as experimental models of multiple sclerosis) and cancer metabolic regulation, and its deficiency is associated with low tRNA modification in tumor cells .

HY-W009162

Cytidine 5'-monophosphate 1 Publications Verification 5'-Cytidylic acid; 5'-CMP	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Metabolic Disease Nervous System Disorder Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group .

HY-I0960

Uracil 4 Publications Verification	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite Drug Derivative
Uracil is a pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. Uracil is a frequently occurring DNA base damage that results from the spontaneous or chemically induced deamination of cytosine and is mutagenic at the level of replication. Uracil could potentially alter transcriptional fidelity, resulting in production of mutant proteins .

HY-B0152B

Adenine hemisulfate Maximum Cited Publications 22 Publications Verification 6-Aminopurine hemisulfate; Vitamin B4 hemisulfate	Structural Classification Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification Cancer	DNA/RNA Synthesis Endogenous Metabolite
Adenine hemisulfate (6-Aminopurine hemisulfate), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hemisulfate acts as a chemical component of DNA and RNA. Adenine hemisulfate also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-41461

5-Amino-3H-imidazole-4-Carboxamide 1 Publications Verification 5-Aminoimidazole-4-carboxamide; AICA	Structural Classification Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
5-Amino-3H-imidazole-4-Carboxamide (5-Aminoimidazole-4-carboxamide; AICA) is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular .

HY-W013159

2'-Deoxyguanosine 5'-monophosphate disodium 1 Publications Verification 5′-dGMP disodium	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Nucleoside Antimetabolite/Analog
2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .

HY-B0152A

Adenine hydrochloride Maximum Cited Publications 22 Publications Verification 6-Aminopurine hydrochloride; Vitamin B4 hydrochloride	Structural Classification Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification Cancer	DNA/RNA Synthesis Endogenous Metabolite
Adenine hydrochloride (6-Aminopurine hydrochloride), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hydrochloride acts as a chemical component of DNA and RNA. Adenine hydrochloride also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-W002272

Isocytosine	Classification of Application Fields Other Diseases Disease Research Fields	Nucleoside Antimetabolite/Analog
Isocytosine is a non-natural nucleobase and an isomer of cytosine. It is used in combination with Isoguanine in studies of unnatural nucleic acid analogues of the normal base pairs in DNA and used as a nucleobase of hachimoji RNA .

HY-69014

2-O-Methylcytosine	Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification Cancer	DNA/RNA Synthesis Endogenous Metabolite
2-O-Methylcytosine, an O-alkylated analogue a DNA adduct, is the damaged nucleobase .

HY-41461A

5-Amino-3H-imidazole-4-carboxamide hydrochloride 1 Publications Verification 5-Aminoimidazole-4-carboxamide hydrochloride; AICA hydrochloride	Microorganisms Source Classification	Endogenous Metabolite
5-Amino-3H-imidazole-4-Carboxamide (AICA) hydrochloride is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular .

HY-N10574A

Queuine dihydrochloride 1 Publications Verification	Alkaloids Microorganisms Pyrrole Alkaloids Source Classification	Others
Queuine dihydrochloride is a selective substrate for tRNA guanine transglycosylase (TGT) and can be incorporated into eukaryotic tRNA. Queuine dihydrochloride promotes tRNA modification, affecting mitochondrial function and Warburg metabolic phenotype. If Queuine dihydrochloride is deficient, aerobic glycolysis can be enhanced, oxidative phosphorylation can be inhibited, and Warburg metabolism can be promoted, accompanied by increased ammonia and lactate production and increased lactate dehydrogenase activity. Queuine dihydrochloride can be used for autoimmune diseases (such as experimental models of multiple sclerosis) and cancer metabolic regulation, and its deficiency is associated with low tRNA modification in tumor cells .

HY-117813

2-Thiouridine	Source Classification	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Dengue Virus Flavivirus CHIKV SARS-CoV
2-Thiouridine is an orally active modified nucleobase. 2-Thiouridine stabilizes U:A base pairs and destabilizes U:G wobble base pairs. 2-Thiouridine significantly improves the efficiency and accuracy of nonenzymatic replication of mixed-sequence A/U-containing RNA templates. 2-Thiouridine exhibits antiviral activity against multiple positive-sense single-stranded RNA viruses (DENV2, ZIKV, YFV, JEV, WNV, CHIKV, human coronaviruses ( [HCoV]-229E, HCoV-OC43, SARS-CoV), and MERS-CoV) .

HY-W010450R

Thymine (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Thymine (Standard) is the analytical standard of Thymine. This product is intended for research and analytical applications. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM.

HY-B0152R

Adenine (Standard)	Structural Classification Natural Products Microorganisms Endogenous metabolite	Reference Standards DNA/RNA Synthesis Endogenous Metabolite
Adenine (Standard) is the analytical standard of Adenine. This product is intended for research and analytical applications. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-W010918R

Adenosine 5'-diphosphate (Standard) Adenosine diphosphate (Standard); ADP (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Endogenous metabolite Cardiovascular System Disorder Source Classification	Reference Standards Endogenous Metabolite
Adenosine 5'-diphosphate (Standard) is the analytical standard of Adenosine 5'-diphosphate. This product is intended for research and analytical applications. Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors. In Vitro: Adenosine 5'-diphosphate consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases. ATP is an important energy transfer molecule in cells. Adenosine 5'-diphosphate is utilized in a wide number of cellular processes, including respiration, biosynthetic reactions, motility, and cell division.

HY-I0960R

Uracil (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite	Reference Standards Endogenous Metabolite
Uracil (Standard) is the analytical standard of Uracil. This product is intended for research and analytical applications. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA.

HY-W015213

Adenine monohydrochloride hemihydrate Maximum Cited Publications 22 Publications Verification	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite DNA/RNA Synthesis
Adenine monohydrochloride hemihydrate is a hydrochloride derivative of Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-N15159

Cladophorol A	Structural Classification Marine algae Marine natural products Phenols Polyphenols Source Classification	Cyclic GMP-AMP Synthase STING Parasite
Cladophorol A is a cyclic GMP-AMP synthase (cGAS) inhibitor. Cladophorol A binds to the conserved adenosine nucleobase binding site within the cGAS active site to inhibit its catalytic activity. Cladophorol A effectively inhibits the overactivation of the cGAS-STING pathway with an IC₅₀ of 370 nM. Cladophorol A inhibits asexual blood-stage Plasmodium falciparum with an EC₅₀ of 0.7 μg/mL. Cladophorol A can be used for the researches of inflammatory disease and malaria .

HY-W009162R

Cytidine 5'-monophosphate (Standard) 5'-Cytidylic acid (Standard); 5'-CMP (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Cytidine 5'-monophosphate (Standard) is the analytical standard of Cytidine 5'-monophosphate. This product is intended for research and analytical applications. Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group .

HY-B0152BR

Adenine hemisulfate (Standard) 6-Aminopurine hemisulfate (Standard); Vitamin B4 hemisulfate (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	DNA/RNA Synthesis Endogenous Metabolite Reference Standards
Adenine (hemisulfate) (Standard) is the analytical standard of Adenine (hemisulfate). This product is intended for research and analytical applications. Adenine hemisulfate (6-Aminopurine hemisulfate), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hemisulfate acts as a chemical component of DNA and RNA. Adenine hemisulfate also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-69014R

2-O-Methylcytosine (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	DNA/RNA Synthesis Endogenous Metabolite Reference Standards
2-O-Methylcytosine (Standard) is the analytical standard of 2-O-Methylcytosine. This product is intended for research and analytical applications. 2-O-Methylcytosine, an O-alkylated analogue a DNA adduct, is the damaged nucleobase .

HY-B0152AR

Adenine hydrochloride (Standard) 6-Aminopurine hydrochloride (Standard); Vitamin B4 hydrochloride (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards DNA/RNA Synthesis Endogenous Metabolite
Adenine (hydrochloride) (Standard) is the analytical standard of Adenine (hydrochloride). This product is intended for research and analytical applications. Adenine hydrochloride (6-Aminopurine hydrochloride), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hydrochloride acts as a chemical component of DNA and RNA. Adenine hydrochloride also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis[1][2][3].

HY-41461R

5-Amino-3H-imidazole-4-Carboxamide (Standard) 5-Aminoimidazole-4-carboxamide (Standard); AICA (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
5-Amino-3H-imidazole-4-Carboxamide (Standard) is the analytical standard of 5-Amino-3H-imidazole-4-Carboxamide. This product is intended for research and analytical applications. 5-Amino-3H-imidazole-4-Carboxamide (AICA) is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular.

HY-41461AR

5-Amino-3H-imidazole-4-carboxamide hydrochloride (Standard) 5-Aminoimidazole-4-carboxamide hydrochloride (Standard); AICA hydrochloride (Standard)	Microorganisms Source Classification	Reference Standards Endogenous Metabolite
5-Amino-3H-imidazole-4-carboxamide (hydrochloride) (Standard) is the analytical standard of 5-Amino-3H-imidazole-4-carboxamide hydrochloride (HY-41461A). This product is intended for research and analytical applications. 5-Amino-3H-imidazole-4-Carboxamide (AICA) hydrochloride is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular .

HY-W015213R

Adenine monohydrochloride hemihydrate (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards DNA/RNA Synthesis
Adenine monohydrochloride hemihydrate (Standard) is the analytical standard of Adenine monohydrochloride hemihydrate (HY-W015213). This product is intended for research and analytical applications. Adenine monohydrochloride hemihydrate is a hydrochloride derivative of Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-W013159R

2'-Deoxyguanosine 5'-monophosphate disodium (Standard) 5′-dGMP disodium (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards Nucleoside Antimetabolite/Analog
2'-Deoxyguanosine 5'-monophosphate (disodium) (Standard) is the analytical standard of 2'-Deoxyguanosine 5'-monophosphate (disodium) (HY-W013159). This product is intended for research and analytical applications. 2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P702435

	SLC23A2 Protein, Human (Cell-Free, His) Solute carrier family 23 member 2; Na(+)/L-ascorbic acid transporter 2; nucleobase transporter-like 1 protein; Sodium-dependent vitamin C transporter 2; hSVCT2; Yolk sac permease-like molecule 2	Human	E. coli Cell-free
	The SLC23A2 protein is a sodium/ascorbic acid cotransporter that significantly promotes the electrical uptake of vitamin C, with a stoichiometry of 2 Na(+) ions per ascorbic acid molecule. Its role is critical in maintaining cellular vitamin C homeostasis, emphasizing its specific and efficient ascorbic acid transport. SLC23A2 Protein, Human (Cell-Free, His) is the recombinant human-derived SLC23A2 protein, expressed by E. coli Cell-free , with C-6*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-B0152S1

Adenine-13C 2 Publications Verification
Adenine- ¹³C is the ¹³C labeled Adenine . Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-B0152S4

Adenine-15N5

Adenine- ¹⁵N₅ (6-Aminopurine- ¹⁵N₅; Vitamin B4- ¹⁵N₅) is ¹⁵N labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.

HY-I0960S4

Uracil-d2
Uracil-d₂ is the deuterium labeled Uracil . Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA .

HY-B0152S

Adenine-d1
Adenine-d is the deuterium labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-W009162S5

Cytidine 5′-monophosphate-13C9,15N3 dilithium

Cytidine 5′-monophosphate- ¹³C₉, ¹⁵N₃ (5'-Cytidylic acid- ¹³C₉, ¹⁵N₃ dilithium; 5'-CMP- ¹³C₉, ¹⁵N₃) dilithium is ¹³C and ¹⁵N-labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.

HY-B0152S3

Adenine-13C5

Adenine- ¹³C₅ (6-Aminopurine- ¹³C₅; Vitamin B4- ¹³C₅) is ¹³C-labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.

HY-I0960S1

Uracil-13C4
Uracil- ¹³C₄ is the ¹³C labeled Uracil . Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA .

HY-I0960S9

Uracil-d4
Uracil-d₄ is the deuterium labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].

HY-B0152S7

Adenine-15N5 hydrochloride hydrate

Adenine- ¹⁵N₅ (6-Aminopurine- ¹⁵N₅) hydrochloride hydrate is the ¹⁵N-labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-I0960S5

Uracil-15N2
Uracil- ¹⁵N₂ is the ¹⁵N labeled Uracil . Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA .

HY-I0960S6

Uracil-d2-1
Uracil-d₂-1 is the deuterium labeled Uracil . Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA .

HY-I0960S3

Uracil-13C4,15N2
Uracil- ¹³C₄, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Uracil . Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA .

HY-W010450S4

Thymine-d4-1
Thymine-d₄-1 is the deuterium labeled Thymine . Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM .

HY-W747214

Thymine-15N2,13C
Thymine- ¹⁵N₂, ¹³C is the ¹³C and ¹⁵N labeled Thymine (HY-W010450). Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-Fluorouracil (HY-90006) in cancer treatment, with a K_m of 2.3 μM .

HY-W013159S

2'-Deoxyguanosine 5'-monophosphate-13C10,15N5 disodium

2'-Deoxyguanosine 5'-monophosphate- ¹³C₁₀, ¹⁵N₅ (dGMP- ¹³C₁₀, ¹⁵N₅) disodium is the ¹³C and ¹⁵N labeled 2'-Deoxyguanosine 5'-monophosphate disodium (HY-W013159). 2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .

HY-I0960S

Uracil-13C2,15N2
Uracil- ¹³C₂, ¹⁵N₂ is the ¹³C-labeled and ¹⁵N-labeled Uracil. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA.

HY-W010450S

Thymine-d4
Thymine-d₄ is the deuterium labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM.

HY-W010450S3

Thymine-13C
Thymine- ¹³C is the ¹³C labeled Thymine . Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM .

HY-B0152S2

Adenine-13C5,15N5

Adenine- ¹³C₅,15C5 (6-Aminopurine- ¹³C₅,15C5; Vitamin B4- ¹³C₅,15C5) is ¹³C-labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.

HY-I0960S7

Uracil-d1
Uracil-d₁ is the deuterium labeled Uracil . Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA .

HY-I0960S2

Uracil-13C
Uracil- ¹³C is the ¹³C labeled Uracil . Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA .

HY-W010450S2

Thymine-15N2
Thymine- ¹⁵N₂ is the ¹⁵N labeled Thymine . Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM .

HY-W009162S

Cytidine 5′-monophosphate-15N3 disodium
Cytidine 5′-monophosphate- ¹⁵N₃ (disodium) is the ¹⁵N labeled Cytidine 5'-monophosphate disodium . Cytidine 5'-monophosphate (5'-Cytidylic acid) disodium is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate disodium consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group .

HY-W010450S5

Thymine-13C5,15N2
Thymine- ¹³C₅, ¹⁵N₂ (5-Methyluacil- ¹³C₅, ¹⁵N₂) is ¹³C and ¹⁵N labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a K_m of 2.3 μM .

HY-W712567

Adenine-15N5 hydrochloride

Adenine- ¹⁵N₅ (6-Aminopurine- ¹⁵N₅) hydrochloride is the ¹⁵N-labeled Adenine hydrochloride (HY-B0152A) . Adenine hydrochloride (6-Aminopurine hydrochloride), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hydrochloride acts as a chemical component of DNA and RNA. Adenine hydrochloride also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.

HY-W015213S

Adenine monohydrochloride hemihydrate-15N5

Adenine monohydrochloride hemihydrate- ¹⁵N₅ is the ¹⁵N labeled Adenine monohydrochloride hemihydrate (HY-W015213). Adenine monohydrochloride hemihydrate is a hydrochloride derivative of Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-W009162S2

Cytidine 5′-monophosphate-d12 dilithium
Cytidine 5′-monophosphate-d₁₂ (5'-Cytidylic acid-d₁₂ dilithium; 5'-CMP-d₁₂) dilithium is deuterium labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.

HY-W009162S4

Cytidine 5′-monophosphate-15N3 dilithium
Cytidine 5′-monophosphate- ¹⁵N₃ (5'-Cytidylic acid- ¹⁵N₃ dilithium; 5'-CMP- ¹⁵N₃) dilithium is ¹⁵N labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.

HY-W009162S1

Cytidine 5′-monophosphate-13C9 dilithium
Cytidine 5′-monophosphate- ¹³C₉ (5'-Cytidylic acid- ¹³C₉ dilithium; 5'-CMP- ¹³C₉) dilithium is ¹³C-labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.

HY-W009162S3

Cytidine 5′-monophosphate-15N3,d12 dilithium

Cytidine 5′-monophosphate- ¹⁵N₃,d₁₂ (5'-Cytidylic acid- ¹⁵N₃,d₁₂ dilithium; 5'-CMP- ¹⁵N₃,d₁₂) dilithium is deuterium and ¹⁵N labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.

HY-I0960S8

Uracil-d1-1
Uracil-d₁-1 is the deuterium labeled Uracil . Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA .

Cat. No.	Product Name		Classification

HY-B0152

Adenine Maximum Cited Publications 22 Publications Verification		Freeze-drying Protective Agents
Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .

HY-W009162

Cytidine 5'-monophosphate 1 Publications Verification 5'-Cytidylic acid; 5'-CMP		Nucleotide Analogs
Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group .

HY-112582A

N1-Methylpseudouridine-5′-triphosphate solution (100 mM) 1 Publications Verification 1-Methylpseudouridine-5′-triphosphate		Nucleotide Analogs
N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability.

HY-W013159

2'-Deoxyguanosine 5'-monophosphate disodium 1 Publications Verification 5′-dGMP disodium		Nucleotide Analogs
2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .

HY-111531

DMTr-LNA-5MeU-3-CED-phosphoramidite		Phosphoramidites Uracil
DMTr-LNA-5MeU-3-CED-phosphoramidite is a Phosphoramidite derivative and Nucleoside derivative .

HY-W749117

Inosine 5′-diphosphate sodium		Nucleotide Analogs Inosine Nucleoside
Inosine 5’-diphosphate sodium is a purine ribonucleoside 5’-diphosphate with inosine as the nucleobase, which can participate in intracellular energy metabolism and signal transduction processes .

HY-159806

UU (3′,5′)-Uridylyluridine		Nucleotide Analogs
UU ((3′,5′)-Uridylyluridine) is a nucleobase-containing dinucleotide derivative. UU can be used for the study of RNA-related processes .

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