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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
91 Results for "
polycyclic
" in MedChemExpress (MCE) Product Catalog:
Products (91)
91 Results for "polycyclic" in MCE Product Catalog:
8
Category:
Infection Microorganisms Antibiotics Disease Research Anticancer Disease Research Fields Other Antibiotics
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4
4 Cited Publications
Cat. No.: HY-W011845
CAS No.: 57-97-6
Synonyms: 7,12-DMBA; 7,12-Dimethylbenzanthracene
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DMBA has carcinogenic activity as a polycyclic aromatic hydrocarbon (PAH). DMBA is used to induce tumor formation in various rodent models .
1
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Phenanthrene is an orally active polycyclic aromatic hydrocarbon (PAH) that induces inflammation, oxidative stress, and apoptosis. Additionally, phenanthrene is commonly used to detect or assess PAH pollution in the environment .
1
1 Cited Publications
Synonyms: Benzo[def]phenanthrene
1
1 Cited Publications
Cat. No.: HY-W026772
CAS No.: 86-73-7
Target:
Environmental Pollutants Fluorescent Dye TNF Receptor Interleukin Related SOD Reactive Oxygen Species (ROS)
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Fluorene is an orally active polycyclic aromatic hydrocarbon (PAH) and a precursor to other fluorene-based compounds. Fluorene and its derivatives serve as dye precursors for fluorene synthesis. In A549 cells, Fluorene induces oxidative stress and inflammatory responses by increasing ROS and SOD generation, exacerbating lipid peroxidation, modulating antioxidant enzyme activity, and upregulating the expression of pro-inflammatory factors TNF-α and IL-6. In vivo, Fluorene exhibits anxiolytic activity. Fluorene holds potential for research in inflammation and neurological disorders .
1
1 Cited Publications
Cat. No.: HY-W013570
CAS No.: 208-96-8
1
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1
1 Cited Publications
Cat. No.: HY-P1206
CAS No.: 174688-78-9
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1
1 Cited Publications
Cat. No.: HY-W127705
CAS No.: 4213-45-0
Cat. No.: HY-W100026
CAS No.: 1222-05-5
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Galaxolide is a polycyclic musk synthetic fragrance. Galaxolide possesses endocrine-disrupting activity and can exert anti-androgenic/estrogenic effects. Galaxolide exhibits in vivo androgenic activity in immature rats . Galaxolide can be used in studies related to endocrine disruption .
Cat. No.: HY-121360
CAS No.: 143545-90-8
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Cat. No.: HY-P10033
CAS No.: 245080-24-4
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Category:
Natural Products Psidium guajava Linn. Other Diseases Myrtaceae Plants Disease Research Fields
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Cat. No.: HY-W014075
CAS No.: 5315-79-7
Cat. No.: HY-W007692
CAS No.: 22047-25-2
Synonyms: 2-Acetylpyrazine
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Acetylpyrazine (2-Acetylpyrazine) is used to form many polycyclic compounds, as useful structures in pharmaceuticals and perfumes. Acetylpyrazine is a component of the folates (vitamin B compounds) .
Cat. No.: HY-W013053
CAS No.: 53-70-3
Synonyms: DBA; 1,2,5,6-Dibenzanthracene; Benzo[k]tetraphene
Research Areas:
Dibenz[a,h]anthracene (DBA) is an orally active polycyclic aromatic hydrocarbon, a by-product of incomplete combustion of organic matter, a potent carcinogen, and an agonist of AhR. Dibenz[a,h]anthracene induces dose-dependent increases in DNA adduct formation and lacZ mutation frequency. Dibenz[a,h]anthracene upregulates St3gal5. Dibenz[a,h]anthracene can be used in cancer-related research .
Cat. No.: HY-W090294
CAS No.: 198-55-0
Synonyms: Peri-dinaphthalene (purified by sublimation)
Research Areas:
Dibenzo (a,i) pyrene is a polycyclic aromatic hydrocarbon and also a carcinogenic ligand of the TCDD (Ah) receptor. Dibenzo (a,i) pyrene binds to the TCDD (Ah) receptor in rat liver. Dibenzo (a,i) pyrene induces DNA adduct formation and upregulates the protein levels of p53 and p21 WAF1 in diploid lung fibroblasts. Dibenzo (a,i) pyrene alters the cell cycle distribution of diploid lung fibroblasts, increasing the proportion of cells in the S phase, decreasing the proportions of cells in the G0/G1 and G2/M phases, and causing S phase delay/arrest. Dibenzo (a,i) pyrene is applicable for cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
