1347 Results for "

polypeptide

" in MedChemExpress (MCE) Product Catalog:
Products (1347)

1347 Results for "polypeptide" in MCE Product Catalog:

105
105 Publications Verification
Cat. No.: HY-P0035A
CAS No.: 11061-68-0
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Insulin solution (human) is a polypeptide hormone that regulates the level of glucose. Insulin solution (human) can be used for the diabetes mellitus .
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105
105 Publications Verification
Cat. No.: HY-P0035
CAS No.: 11061-68-0
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease Endocrinology

Insulin (human) is a polypeptide hormone that regulates the level of glucose. Insulin (human) can be used for the diabetes mellitus .
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48
48 Cited Publications
Cat. No.: HY-10465
CAS No.: 1009119-65-6
Purity:  99.68%
Synonyms: BMS-790052 dihydrochloride; EBP 883 dihydrochloride
Target:  

HCV

Research Areas:  

Infection

Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir dihydrochloride is also an organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 μM and 3.27 μM, respectively .
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48
48 Cited Publications
Cat. No.: HY-10466
CAS No.: 1009119-64-5
Purity:  98.68%
Synonyms: BMS-790052; EBP 883
Target:  

HCV

Research Areas:  

Infection

Daclatasvir (BMS-790052) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 µM and 3.27 µM, respectively .
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31
31 Cited Publications
Cat. No.: HY-113678
CAS No.: 1066-17-7
Synonyms: Polymyxin E
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Colistin is an orally active polypeptide antibiotic. Colistin has excellent activity against various Gram-negative rod-shaped bacteria, including multidrug-resistant Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumoniae. Colistin is associated with nephrotoxicity. Colistin can be used for the research of infections caused by Gram-negative bacilli .
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31
31 Cited Publications
Cat. No.: HY-A0089
CAS No.: 1264-72-8
Synonyms: Polymyxin E sulfate
Colistin sulfate is a polypeptide antibiotic which inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria.
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29
29 Cited Publications
Cat. No.: HY-P7055
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDGFB; Platelet-Derived Growth Factor 2; Prev. SIS; PDGF Subunit B; Platelet-Derived Growth Factor Beta polypeptide; PDGF2; Platelet-Derived Growth Factor Subunit B; Platelet-Derived Growth Factor, Beta polypeptide (Oncogene SIS); Platelet-Derived Growth
Species:  
Human
Source:  
E. coli
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26
26 Cited Publications
Cat. No.: HY-13207
CAS No.: 960374-59-8
Purity:  99.72%
Synonyms: PR-957
Target:  

Proteasome Bacterial HIV

Research Areas:  

Infection Inflammation/Immunology

ONX-0914 (PR-957) is a selective inhibitor of low-molecular mass polypeptide-7 (LMP7), the chymotrypsin-like subunit of the immunoproteasome. ONX-0914 blocks cytokine production and attenuates progression of experimental arthritis. ONX-0914 is a noncompetitive irreversible inhibitor of the mycobacterial proteasome (Ki=5.2 μM). ONX-0914 reactivates latent HIV-1 through p-TEFb activation mediated by HSF-1 .
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26
26 Cited Publications
Cat. No.: HY-P1731C
Synonyms: LY3298176 sodium
Tirzepatide sodium (LY3298176 sodium) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. Tirzepatide sodium exerts anti-apoptotic and pro-differentiation effects via the pAkt/CREB/BDNF cascade and miRNA in neurons; in the heart, it promotes BCAA catabolism and inhibits the mTOR pathway by mediating the dephosphorylation of BCKDHA; meanwhile, it effectively reduces insulin and leptin levels and suppresses inflammatory responses at the systemic level. Tirzepatide sodium can be used for research on myocardial infarction, colon cancer, diabetes, diabetic cognitive impairment, neurodegeneration, diabetes-related neuropathy, and obesity .
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26
26 Cited Publications
Cat. No.: HY-13207A
Purity:  98.01%
Synonyms: PR-957 TFA
Target:  

Proteasome Bacterial HIV

Research Areas:  

Infection Inflammation/Immunology

ONX-0914 (PR-957) TFA is a selective inhibitor of low-molecular mass polypeptide-7 (LMP7), the chymotrypsin-like subunit of the immunoproteasome. ONX-0914 TFA blocks cytokine production and attenuates progression of experimental arthritis. ONX-0914 TFA is a noncompetitive irreversible inhibitor of the mycobacterial proteasome (Ki=5.2 μM). ONX-0914 TFA reactivates latent HIV-1 through p-TEFb activation mediated by HSF-1 .
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24
24 Cited Publications
Cat. No.: HY-B0467A
CAS No.: 26787-78-0
Synonyms: Amoxycillin
Target:  

Bacterial Antibiotic

Research Areas:  

Infection Cancer

Amoxicillin (Amoxycillin) is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
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24
24 Cited Publications
Cat. No.: HY-B0467B
CAS No.: 61336-70-7
Synonyms: Amoxycillin trihydrate
Target:  

Bacterial Antibiotic

Research Areas:  

Infection Metabolic Disease Cancer

Amoxicillin (Amoxycillin) trihydrateis an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin trihydrateis inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
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24
24 Cited Publications
Cat. No.: HY-B0467
CAS No.: 34642-77-8
Synonyms: Amoxycillin sodium
Target:  

Bacterial Antibiotic

Research Areas:  

Infection Cancer

Amoxicillin (Amoxycillin) sodium is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin sodium inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
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24
24 Cited Publications
Cat. No.: HY-D0802
CAS No.: 35013-72-0
Synonyms: Biotin N-hydroxysuccinimide ester; NHS-Biotin
Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.
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19
19 Cited Publications
Cat. No.: HY-P0118
CAS No.: 272105-42-7
Synonyms: P144
Research Areas:  

Cancer

Disitertide (P144) is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide (P144) is also a PI3K inhibitor and an apoptosis inducer .
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19
19 Cited Publications
Cat. No.: HY-P0118B
Synonyms: P144 diammonium
Research Areas:  

Cancer

Disitertide (P144) diammonium is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide diammonium is also a PI3K inhibitor and an apoptosis inducer .
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17
17 Cited Publications
Cat. No.: HY-P1156
CAS No.: 11070-73-8
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease Endocrinology

Insulin cattle is a two-chain polypeptide hormone produced in vivo in the pancreatic β cells. Insulin cattle has often been used as growth supplement in culturing cells.
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13
13 Cited Publications
Cat. No.: HY-P7278
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDGFB; Platelet-Derived Growth Factor 2; Prev. SIS; PDGF Subunit B; Platelet-Derived Growth Factor Beta polypeptide; PDGF2; Platelet-Derived Growth Factor Subunit B; Platelet-Derived Growth Factor, Beta polypeptide (Oncogene SIS); Platelet-Derived Growth
Species:  
Rat
Source:  
E. coli
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10
10 Cited Publications
Cat. No.: HY-P7087
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDGFB; Platelet-Derived Growth Factor 2; Prev. SIS; PDGF Subunit B; Platelet-Derived Growth Factor Beta polypeptide; PDGF2; Platelet-Derived Growth Factor Subunit B; Platelet-Derived Growth Factor, Beta polypeptide (Oncogene SIS); Platelet-Derived Growth
Species:  
Mouse
Source:  
E. coli
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9
9 Cited Publications
Cat. No.: HY-78695
CAS No.: 202592-23-2
JQ-1 carboxylic acid, a (+)-JQ-1 (HY-13030) derivative, is a potent BET bromodomain inhibitor. JQ-1 carboxylic acid can be used to synthesize PROTAC, which can target the degradation of BRD4.
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