Search Result

Results for "

taste

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Taste Receptor (18) 5-HT Receptor (2) Amino Acid Derivatives (3) Apoptosis (3) Autophagy (2) Bacterial (7) Biochemical Assay Reagents (16) Cannabinoid Receptor (1) Caspase (2) Dopamine Receptor (1) Drug Derivative (6) Drug Metabolite (3) EBV (1) Endogenous Metabolite (23) Environmental Pollutants (10) Epigenetic Reader Domain (2) Fatty Acid Synthase (FASN) (1) Fluorescent Dye (1) Fungal (1) Glycosidase (2) HMG-CoA Reductase (HMGCR) (1) Insecticide (3) Isotope-Labeled Compounds (11) Keap1-Nrf2 (2) LDLR (1) mAChR (1) MDM-2/p53 (2) MMP (2) Necroptosis (2) Opioid Receptor (1) P2X Receptor (1) Parasite (3) PARP (2) Reactive Oxygen Species (ROS) (2) Reference Standards (16) TRP Channel (3)
By Research Areas:	Cancer (5) Cardiovascular Disease (1) Endocrinology (1) Infection (8) Inflammation/Immunology (11) Metabolic Disease (25) Neurological Disease (10)
Oligonucleotides:	Preservatives (2) Flavoring Agents (1)

100

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Targets Recommended: Taste Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-41417

Octanoic acid 3 Publications Verification Caprylic acid	Environmental Pollutants Endogenous Metabolite	Metabolic Disease
Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes. Octanoic acid is also a tremor-suppressing agent .

HY-Y1069

(S)-Malic acid 2 Publications Verification (S)-Hydroxybutanedioic acid; (S)-E 296; L-Malic acid	Endogenous Metabolite	Metabolic Disease
(S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive.

HY-W030796A

Lactisole 3 Publications Verification	Taste Receptor	Metabolic Disease
Lactisole is a canonical antagonist of sweet taste receptor, selectively targeting to T1R3 subunit, a glucose-sensing receptor. Lactisole inhibits insulin secretion induced by glucose in mouse islets .

HY-N0466

Rebaudioside A	Glycosidase HMG-CoA Reductase (HMGCR) Fatty Acid Synthase (FASN) LDLR	Others
Rebaudioside A is an orally effective steviol glycoside with high sweetness. Rebaudioside A acts as an inhibitor of α-glucosidase with an IC₅₀ value of 35.01 μg/mL. Rebaudioside A increases the ATP/ADP ratio in β cells in a glucose-dependent manner, thereby inhibiting KATP channels, leading to membrane depolarization, calcium influx, and ultimately stimulating insulin secretion. Rebaudioside A activates the SREBP signaling pathway by inhibiting HMGCR, the rate-limiting enzyme in cholesterol synthesis, resulting in increased expression of LDLR on the cell surface, thus promoting the uptake of LDL-C in the blood. Rebaudioside A can be used for studies on blood glucose and lipid regulation as well as anti-obesity .

HY-100047

Nα,Nα-Bis(carboxymethyl)-L-lysine	Taste Receptor	Others
Nα,Nα-Bis(carboxymethyl)-L-lysine is a competitive inhibitor of *bitter taste* receptor 4, with an IC₅₀** of 59 nM. Nα,Nα-Bis(carboxymethyl)-L-lysine can be used in bitter receptors related study .

HY-W007035

H-Val-Ala-OH 1 Publications Verification Valyl-alanine	Endogenous Metabolite Amino Acid Derivatives	Metabolic Disease
H-Val-Ala-OH (Valyl-alanine) is a dipeptide formed from L-Valine and L-Alanine residues. H-Val-Ala-OH has a role as a metabolite and also has a bitter taste .

HY-W012995

5-Hexen-1-ol	Biochemical Assay Reagents	Others
5-Hexen-1-ol, is an aromatic substance with aromas similar to substances such as herbs, tea and citrus. Therefore, it is usually used in the food, fragrance and perfume industries, and is widely used in the preparation of various food flavors, fragrances, taste flavoring agents, essential oils and cosmetics and other products.

HY-136026

Camlipixant BLU-5937	P2X Receptor	Inflammation/Immunology
Camlipixant (BLU-5937) a potent, selective, non-competitive and orally active P2X3 homotrimeric receptor antagonist with an IC₅₀ of 25 nM against hP2X3 homotrimeric. Camlipixant shows potent anti-tussive effect and no taste alteration. Camlipixant can be used for the research of unexplained, refractory chronic cough .

HY-139338

Erlose 1 Publications Verification	Glycosidase	Others
Erlose is a trisaccharide sucrose derivative and low-calorie sweetener synthesized from glucose and sucrose via an α-glucosidase-mediated transglycosylation reaction. Erlose is often used as a marker to identify whether honey is adulterated with artificial sucrose. Erlose has approximately half the sweetness of sucrose but a similar taste, and it effectively inhibits crystal formation and browning reactions during food heat treatment .

HY-W010607

cis-3-Hexen-1-ol (Z)-3-Hexen-1-ol	Environmental Pollutants	Neurological Disease
cis-3-Hexen-1-ol ((Z)-3-Hexen-1-ol) is a green grassy smelling compound found in many fresh fruits and vegetables with bitter taste enhancement. cis-3-Hexen-1-ol is widely used as an added flavor in processed food to provide a fresh green quality. cis-3-Hexen-1-ol is an attractant to various insects .

HY-N0467

Rebaudioside C Dulcoside B	Endogenous Metabolite	Neurological Disease
Rebaudioside C (Dulcoside B) is an orally effective natural sweetener that cannot pass the blood-brain barrier and selectively binds to human sweet taste receptors (TAS1R2/TAS1R3). The sweetness of Rebaudioside C is about 20-30 times that of sucrose, and its sweetness activity depends on the C-16/C-17 double bond structure and specific aglycones. The glycoside structure in the Rebaudioside C molecule can bind to the sweet taste receptor, activate the taste signal transduction pathway, and produce sweetness perception .

HY-W015339

Octanoate, 99% sodium 3 Publications Verification	Environmental Pollutants Biochemical Assay Reagents	Neurological Disease Metabolic Disease
Octanoate, 99% sodium is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes. Octanoate, 99% sodium is also an orally active tremor-suppressing agent .

HY-D0887

Disodium 5'-inosinate 1 Publications Verification IMP disodium salt; Disodium inosinate	Others	Metabolic Disease
Disodium 5'-inosinate (IMP disodium salt) is a nucleotide-based umami agent. Disodium 5'-inosinate can bind to umami receptors and stimulate taste nerves, allowing the brain to perceive umami. In addition, Disodium 5'-inosinate produces a transient behavioral excitement in mice .

HY-B1146

Denatonium benzoate 1 Publications Verification THS-839	Environmental Pollutants Insecticide	Inflammation/Immunology Endocrinology
Denatonium benzoate (THS-839) is known as the most bitter compound and is commonly used as a deterrent (bittering agent) to activate different types of bitter taste receptors (TAS2Rs) with oral activity. Denatonium benzoate can enhance insulin secretion, has anti-inflammatory effects, and promotes allergy susceptibility .

HY-111664

(R)-(+)-Citronellal (+)-Citronellal	Bacterial Fungal Insecticide Taste Receptor Opioid Receptor	Infection Neurological Disease Inflammation/Immunology
(R)-(+)-Citronellal ((+)-Citronellal) is a monoterpenoid compound and is one of the main components of essential oils from plants such as lemon grass. (R)-(+)-Citronellal has antibacterial, antifungal, and insecticidal activities. (R)-(+)-Citronellal alleviates the bitterness of caffeine by antagonizing the bitter taste receptors Tas2r43 (IC₅₀ = 84 μM) and Tas2R46. (R)-(+)-Citronellal generates analgesic activity by activating the opioid receptor (broad-spectrum opioid receptor) pathway, and its effect is particularly significant for inflammatory pain .

HY-117215

β-Ocimene	Environmental Pollutants Biochemical Assay Reagents	Others
Beta-Ocimene is a naturally occurring organic compound that belongs to the terpene family. It exists as a mixture of three isomers: cis β-Ocimene, trans β-Ocimene and myrcene-like β-Ocimene. It has a pleasant, sweet herbaceous scent and is found in many plants, including mint, basil, parsley, and kumquat. β-Ocimene is widely used in the flavor and fragrance industry due to its characteristic aroma and taste. It also has potential applications in agriculture as natural insect repellants and pheromones that attract beneficial insects. β-Ocimene has potential anti-inflammatory and anticancer activities.

HY-N10319

Artepillin C	Epigenetic Reader Domain Necroptosis TRP Channel	Metabolic Disease Inflammation/Immunology Cancer
Artepillin C is an orally active CREB/CRTC2 inhibitor and TRPA1 covalent agonist (EC₅₀=1.8 μM). Artepillin C inhibits CREB/CRTC2-mediated gene transcription and downregulates BMAL1 expression to regulate glucose and lipid metabolism. Artepillin C can also activate TRPA1 channels to induce spicy taste signals. Artepillin C can inhibit tumor cell proliferation, induce necroptosis, improve insulin resistance and inhibit liver lipid synthesis. Artepillin C can be used in the study of metabolic syndrome, tumor prevention and treatment, and inflammation .

HY-N2084

Perillartine 2 Publications Verification DL-Perillartine	Endogenous Metabolite	Others
Perillartine is a sweetener, which activates the taste receptor type 1 member 2 (Tas1r2) subunit in a species-dependent manner.

HY-N6808

Rebaudioside B	Others	Others
Rebaudioside B is the minor constituent isolated from the leaves of Stevia rebaudiana Bertoni. Rebaudioside B tastes about 150 times sweeter than sucrose. Rebaudioside B can hydrolysis to steviol .

HY-N0917

6''-O-Malonylgenistin 1 Publications Verification Malonylgenistin; Genistin malonate	Drug Metabolite Taste Receptor	Others
6''-O-Malonylgenistin (Malonylgenistin) is a glycosylated isoflavone and metabolite of Genistin (HY-N0595). 6''-O-Malonylgenistin activates hTAS2R39. 6''-O-Malonylgenistin can be used in the research of bitter taste .

HY-P4648

H-Trp-Trp-Trp-OH Trp-Trp-Trp	Bacterial	Infection
H-Trp-Trp-Trp-OH (Trp-Trp-Trp) is a tripeptide consisting of tryptophan. H-Trp-Trp-Trp-OH has antibacterial activity. H-Trp-Trp-Trp-OH is a human bitter taste receptor hTAS2R14 agonist .

HY-136429A

Ethylhydrocupreine hydrochloride Optochin hydrochloride	Bacterial Parasite	Infection
Ethylhydrocupreine hydrochloride (Optochin hydrochloride) is a quinine derivate with antimicrobial activity against *S. pneumoniae. Ethylhydrocupreine hydrochloride also possesses antimalarial activity against Plasmodium falciparum, with an IC₅₀* of 25.75 nM. Ethylhydrocupreine hydrochloride is a Gallus gallus taste 2 receptors (ggTas2r1, ggTas2r2 and ggTas2r7) agonist .

HY-153265

TAS2R14 agonist-2	Taste Receptor	Inflammation/Immunology
TAS2R14 agonist-2 (compound 28.1) is a potent and selective TAS2R14 agonist with an EC₅₀ value of 72 nM. TAS2R14 agonist-2 reveals marked selectivity over a panel of 24 non-bitter taste human G protein-coupled receptors. TAS2R14 agonist-2 can be used for the studies of asthma or chronic obstructive pulmonary disease .

HY-122351A

Advantame	Taste Receptor	Others
Advantame is an N-substituted derivative of aspartame. Advantame is a high-intensity, low calorie sweetener. Advantame can interact with plasma protein. Advantame has the potential to produce hypotension and inhibit hERG K ⁺ channel to produce carditoxicity. Advantame binds to T1R2/T1R3 taste GPCR to form an oligomeric functional selectivity of biased heteromers with NMBR to induce a significant sialidase activity in vitro. Advantame has maternal toxicity (gastrointestinal disturbances) in the prenatal developmental toxicity study in rabbits .

HY-139091

FEMA 4774	Taste Receptor	Others
FEMA 4774 is a positive allosteric modulator of taste receptors T1R2 and T1R3, two subunits of the human sweet taste receptor. FEMA 4774 is also used as a sucrose sweetness enhancer .

HY-N6992

Dulcoside A	Taste Receptor	Inflammation/Immunology
Dulcoside A is a glycoside that can be isolated from Stevia rebaudiana that elicits sweet and bitter taste through activation of TAS1R. Dulcoside A also exhibits anti-inflammatory activity .

HY-41417S4

Octanoic acid-13C4 Caprylic acid-¹³C₄	Endogenous Metabolite	Metabolic Disease
Octanoic acid- ¹³C₄ is the ¹³C labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.

HY-W030796

Lactisole free acid 3 Publications Verification	Taste Receptor	Metabolic Disease
Lactisole free acid is a canonical antagonist of sweet taste receptor, selectively targeting to T1R3 subunit, a glucose-sensing receptor. Lactisole free acid inhibits insulin secretion induced by glucose in mouse islets .

HY-110206

AM6545	Cannabinoid Receptor	Metabolic Disease
AM6545 is a highly selective, brain-free (peripherally active) CB1 receptor antagonist (K_i=1.7 nM). AM6545 inhibits endocannabinoid signaling by competitively antagonizing CB1 receptors, inhibiting CB1-mediated appetite stimulation and inflammatory responses without affecting cAMP levels. AM6545 significantly reduces food intake and body weight in mice, while improving metabolic syndrome-related renal impairment (such as proteinuria, fibrosis) and insulin resistance. AM6545 can be used in the study of obesity and its complications .

HY-N8210

Homoeriodictyol	Drug Metabolite Autophagy Apoptosis Reactive Oxygen Species (ROS) Keap1-Nrf2 MMP Caspase PARP MDM-2/p53	Neurological Disease Inflammation/Immunology Cancer
Homoeriodictyol is an orally active, bitter-tasting flavanone that can penetrate the blood-brain barrier. Homoeriodictyol enhances synaptic-related protein expression through NCOA4-mediated ferritin autophagy. Homoeriodictyol improves memory impairment in mice by inhibiting the NLRP3 inflammasome. Homoeriodictyol protects human endothelial cells from oxidative damage by activating Nrf2 and inhibiting mitochondrial dysfunction. Homoeriodictyol enhances ROS activity and induces apoptosis, exhibiting anticancer effects. Homoeriodictyol inhibits the survival and migration of androgen-resistant prostate cancer cells in vitro. Homoeriodictyol exerts antinociceptive activity in mice in vivo .

HY-106432A

Sabcomeline hydrochloride SB-202026 hydrochloride; Memric hydrochloride	mAChR Dopamine Receptor	Neurological Disease
Sabcomeline (SB-202026; Memric) hydrochloride is a muscarinic receptor agonist capable of crossing the blood-brain barrier. Sabcomeline hydrochloride exhibits affinity for all hM1 to hM5 subtypes (pK_i=6.72-7.23), and shows near-full agonism at the hM3 receptor, inducing extracellular acidification. Sabcomeline hydrochloride alters the binding kinetics of dopamine D2 receptors through neural network regulation. Sabcomeline hydrochloride also causes minimal cardiovascular changes, effectively reverses spatial memory deficits in rodents and induces conditioned taste aversion. Sabcomeline hydrochloride is an important tool compound in studies of Alzheimer's disease and related neurodegenerative diseases .

HY-B1390A

Saccharin sodium	Environmental Pollutants Bacterial	Infection
Saccharin sodium is an orally active, non-caloric artificial sweetener (NAS). Saccharin sodium has bacteriostatic and microbiome-modulating properties. Saccharin binds to and signals via specific taste receptors, not only in the oral cavity but also alongside the gastrointestinal tract. Saccharin has been reported to bind the human and rodent heteromeric guanine nucleotide-binding protein (G protein) coupled sweet taste receptors T1R2/T2R3 as well as the human bitter taste receptor T2R43 and T2R44. Saccharin can inhibit bacterial growth in vitro .

HY-119309

Sucrose octaacetate	Environmental Pollutants Biochemical Assay Reagents	Others
Sucrose octaacetate is an acetylated derivative of sucrose with an intensely bitter tasting and can be used as bitter tasting surrogate. Sucrose octaacetate can be used as food additive and also used as an adhesive and plasticizer. Sucrose octaacetate also used in many pesticides, insecticides, and other toxic products as a deterrent to accidental poisoning. Sucrose octaacetate can also be used as an in situ seed and a soft template to synthesize polyaniline (PANI) nanofibers .

HY-N0742

Absinthin	Others	Others
Absinthin is a structurally unique triterpene, and is responsible for the high bitter value of wormwood. Absinthin is an agonist of the bitter taste receptor hTAS2R46, which reduces cytosolic Ca ²⁺-rises induced by histamine by a receptor-specific mechanism mediated by hTAS2R46 .

HY-W068700

Methyl sorbate	Biochemical Assay Reagents	Others
Methyl sorbate, which is an ester formed by the condensation of methanol and hexa-2,4-dienoic acid, is commonly used as a flavoring agent and fragrance in the food and cosmetic industries due to its fruity, floral, and taste, and in addition , it has also been investigated for its potential use as a starting material in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and polymers.

HY-W076441

Ethyl (S)-3-hydroxybutanoate Ethyl (S)-3-hydroxybutyrate	Biochemical Assay Reagents	Others
Ethyl (S)-3-hydroxybutanoate, also known as (S)-ethyl lactate, which is an ester formed by the condensation of ethanol and (S)-3-hydroxybutanoate, is known for its fruity, sweet smell and taste , which are commonly used as flavoring agents and fragrances in the food and cosmetic industries, and in addition, its potential use as a starting material for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals, has been investigated.

HY-41417R

Octanoic acid (Standard) 3 Publications Verification Caprylic acid (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Octanoic acid (Standard) is the analytical standard of Octanoic acid. This product is intended for research and analytical applications. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.

HY-Y1069S

(S)-Malic acid-d3 1 Publications Verification (S)-Hydroxybutanedioic acid-d₃; (S)-E 296-d₃; L-Malic acid-d₃	Endogenous Metabolite	Metabolic Disease
(S)-Malic acid-d₃ is the deuterium labeled (S)-Malic acid. (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive .

HY-W142618

D-Glucal	Biochemical Assay Reagents	Others
D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.

HY-N7438

Mogroside VI A	Others	Others
Mogroside VI A, an isomer of Mogroside VI isolated from Luo Han Guo, exerts sweetness property. Mogroside VI A can be used for sweetener and/or taste modifier research .

HY-41417S3

Octanoic acid-13C Caprylic acid-¹³C	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Octanoic acid- ¹³C is the ¹³C labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.

HY-41417S

Octanoic acid-d15 Caprylic acid-d₁₅	Endogenous Metabolite	Metabolic Disease
Octanoic acid-d₁₅ is the deuterium labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.

HY-Y1069R

(S)-Malic acid (Standard) 1 Publications Verification (S)-Hydroxybutanedioic acid (Standard); (S)-E 296 (Standard); L-Malic acid (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
(S)-Malic acid (Standard) is the analytical standard of (S)-Malic acid (HY-Y1069). This product is intended for research and analytical applications. (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive.

HY-W012885

(S)-Methyl 3-hydroxybutanoate	Biochemical Assay Reagents	Others
(S)-Methyl 3-hydroxybutanoate consists of a chiral center, resulting in two enantiomers, where (S)-Methyl 3-hydroxybutanoate means that the hydroxyl group is located on the third carbon atom of the S-configuration carboxylic acid group stereoisomers. This compound is often used as a building block for the synthesis of various pharmaceuticals and natural products. Due to its fruity taste, it is also used as a flavor and fragrance ingredient.

HY-N10319R

Artepillin C (Standard)	Reference Standards TRP Channel Necroptosis Epigenetic Reader Domain	Metabolic Disease Inflammation/Immunology Cancer
Artepillin C (Standard) is the analytical standard of Artepillin C (HY-N10319). This product is intended for research and analytical applications. Artepillin C is an orally active CREB/CRTC2 inhibitor and TRPA1 covalent agonist (EC₅₀=1.8 μM). Artepillin C inhibits CREB/CRTC2-mediated gene transcription and downregulates BMAL1 expression to regulate glucose and lipid metabolism. Artepillin C can also activate TRPA1 channels to induce spicy taste signals. Artepillin C can inhibit tumor cell proliferation, induce apoptosis, improve insulin resistance and inhibit liver lipid synthesis. Artepillin C can be used in the study of metabolic syndrome, tumor prevention and treatment, and inflammation .

HY-136429

Ethylhydrocupreine Optochin	Bacterial Parasite	Infection
Ethylhydrocupreine (Optochin) is a quinine derivate with antimicrobial activity against *S. pneumoniae. Ethylhydrocupreine also possesses antimalarial activity against Plasmodium falciparum, with an IC₅₀* of 25.75 nM. Ethylhydrocupreine is a Gallus gallus taste 2 receptors (ggTas2r1, ggTas2r2 and ggTas2r7) agonist .

HY-W016979

δ-Decalactone	Environmental Pollutants	Others
δ-Decalactone is a lactone compound found in nonfat dry milks and fruit. δ-Decalactone has a sweet taste .

HY-41417S1

Octanoic acid-d3 Caprylic acid-d₃	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Octanoic acid-d₃ is the deuterium labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.

HY-W007035R

H-Val-Ala-OH (Standard) Valyl-alanine (Standard)	Reference Standards Endogenous Metabolite Amino Acid Derivatives	Metabolic Disease
H-Val-Ala-OH (Valyl-alanine) is a dipeptide formed from L-Valine and L-Alanine residues. H-Val-Ala-OH has a role as a metabolite and also has a bitter taste .

HY-W017562

γ-Octalactone	Environmental Pollutants Biochemical Assay Reagents	Others
γ-Octalactone is an aromatic lactone compound. γ-Octalactone has a strong fruity (similar to coconut) aroma and a sweet taste, and is commonly used in food, cosmetics and fragrances. γ-Octalactone is highly safe .

Cat. No.	Product Name

HY-L202

Flavor Compound Library

442 compounds

Flavor is an expression of smell and taste that is achieved through a variety of chemical processes triggered by molecules. Food flavor is an important attribute of food quality and in some cases determines consumers' food preferences. In addition to playing a key role in taste and smell, flavor molecules can also be involved in regulating metabolism and have an impact on health. In daily life, flavor molecules have absolute application value in food and spices. In scientific research, the study of flavor molecules is helpful to reveal the relationship between food intake and taste perception. Research on the combination behavior of flavor and food components can explore the retention, release and perception of flavor molecules. Most importantly, while exploring multi-sensory flavor perception, the food industry can fully mobilize the enthusiasm of researching new strategies for delicious and healthy food design.

Based on the FlavorDB database, collects and organizes 442 flavor molecules, which can be used in taste perception and other related studies.

HY-L093

Food Additive Library

454 compounds

Food additives are substances added to food to maintain or improve its safety, freshness, taste, texture, or appearance. All food additives used in food undergo a safety assessment, which includes rigorous testing, before they are approved, so all food additives are generally recognized as safe substances.

MCE supplies 454 approved food additives which are safe substances and can be used for drug discovery and other research.

HY-L242

Flavors and Fragrances Compound Library

500 compounds

Flavors and fragrances serve as indispensable enhancing elements in modern industries, playing multidimensional roles in the fields of food, cosmetics, and pharmaceutical development. In the food industry, flavors and fragrances are not only used to compensate for flavor loss during processing but also to create novel sensory experiences and enhance product appeal. Natural flavors such as vanilla and citrus oils impart rich, layered aromas to foods, while synthetic flavors can precisely replicate specific tastes, meeting the demands of standardized production and extending the flavor stability of food products. In the cosmetics sector, flavors and fragrances are key to emotional design. They enhance product recognition and elevate the pleasure of use through pleasant scents. In pharmaceutical development, the application of flavors and fragrances focuses on improving compliance. Especially in formulations such as oral liquids and chewable tablets, the addition of mint, fruit, and other flavoring components effectively masks the bitter or irritating taste of medications, increasing patient acceptance. Additionally, some natural flavors may themselves possess auxiliary therapeutic benefits.

MCE contains 500 kinds of flavors and fragrances, which can be used in fields such as food, cosmetics and drug development.

Cat. No.	Product Name	Type

HY-W012995

5-Hexen-1-ol	Biochemical Assay Reagents
5-Hexen-1-ol, is an aromatic substance with aromas similar to substances such as herbs, tea and citrus. Therefore, it is usually used in the food, fragrance and perfume industries, and is widely used in the preparation of various food flavors, fragrances, taste flavoring agents, essential oils and cosmetics and other products.

HY-W015339

Octanoate, 99% sodium 3 Publications Verification	Biochemical Assay Reagents
Octanoate, 99% sodium is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes. Octanoate, 99% sodium is also an orally active tremor-suppressing agent .

HY-117215

β-Ocimene

Biochemical Assay Reagents

Beta-Ocimene is a naturally occurring organic compound that belongs to the terpene family. It exists as a mixture of three isomers: cis β-Ocimene, trans β-Ocimene and myrcene-like β-Ocimene. It has a pleasant, sweet herbaceous scent and is found in many plants, including mint, basil, parsley, and kumquat. β-Ocimene is widely used in the flavor and fragrance industry due to its characteristic aroma and taste. It also has potential applications in agriculture as natural insect repellants and pheromones that attract beneficial insects. β-Ocimene has potential anti-inflammatory and anticancer activities.

HY-W068700

Methyl sorbate

Biochemical Assay Reagents

Methyl sorbate, which is an ester formed by the condensation of methanol and hexa-2,4-dienoic acid, is commonly used as a flavoring agent and fragrance in the food and cosmetic industries due to its fruity, floral, and taste, and in addition , it has also been investigated for its potential use as a starting material in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and polymers.

HY-W076441

Ethyl (S)-3-hydroxybutanoate

Ethyl (S)-3-hydroxybutyrate

Biochemical Assay Reagents

Ethyl (S)-3-hydroxybutanoate, also known as (S)-ethyl lactate, which is an ester formed by the condensation of ethanol and (S)-3-hydroxybutanoate, is known for its fruity, sweet smell and taste , which are commonly used as flavoring agents and fragrances in the food and cosmetic industries, and in addition, its potential use as a starting material for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals, has been investigated.

HY-W142618

D-Glucal

Biochemical Assay Reagents

D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.

HY-W012885

(S)-Methyl 3-hydroxybutanoate

Biochemical Assay Reagents

(S)-Methyl 3-hydroxybutanoate consists of a chiral center, resulting in two enantiomers, where (S)-Methyl 3-hydroxybutanoate means that the hydroxyl group is located on the third carbon atom of the S-configuration carboxylic acid group stereoisomers. This compound is often used as a building block for the synthesis of various pharmaceuticals and natural products. Due to its fruity taste, it is also used as a flavor and fragrance ingredient.

HY-W127403

Cholesteryl elaidate

Cholesteryl trans-9-octadecenoate

Biochemical Assay Reagents

Cholesteryl elaidate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and elaidic acid, producing a white crystalline solid with a mildly sweet taste. Cholesteryl elaidate has several applications in the pharmaceutical industry, particularly as a bioactive compound with potential research potential for improving a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.

HY-W099750

Methyl 3-oxoheptanoate Methyl Valerylacetate	Biochemical Assay Reagents
Methyl 3-oxoheptanoate is the methyl ester of the organic compound 3-oxoheptanoate. It has a fruity smell and taste. Methyl 3-oxoheptanoate is widely used as a flavoring agent and fragrance in the food and fragrance industry for its pleasant aroma. It is also used as an intermediate in the synthesis of other organic compounds such as pharmaceuticals, agrochemicals, and polymers.

HY-W068214

Methyl undec-10-enoate Methyl-10-undecenoate	Biochemical Assay Reagents
Methyl undec-10-enoate, which is an ester formed by the condensation of methanol and undec-10-enoic acid, is commonly used as a flavoring and fragrance in the food and cosmetic industries due to its sweet fruity smell and taste , in addition, its potential use in biofuel production and as a starting material for the synthesis of various organic compounds was investigated.

HY-W127447

Maleate trihydrate sodium

Maleic acid sodium

Biochemical Assay Reagents

Maleate trihydrate sodiumIt is an organic compound belonging to the salt class. It is formed from the neutralization reaction between maleic acid and sodium hydroxide and has a slightly bitter taste. Maleate trihydrate sodiumIt has a variety of applications in industrial settings, especially as an intermediate in the synthesis of various chemicals and polymers. Additionally, it is used in the food and beverage industry as a buffer, flavor enhancer and preservative.

Cat. No.	Product Name	Target	Research Area

HY-100047

Nα,Nα-Bis(carboxymethyl)-L-lysine	Taste Receptor	Others
Nα,Nα-Bis(carboxymethyl)-L-lysine is a competitive inhibitor of *bitter taste* receptor 4, with an IC₅₀** of 59 nM. Nα,Nα-Bis(carboxymethyl)-L-lysine can be used in bitter receptors related study .

HY-P4648

H-Trp-Trp-Trp-OH Trp-Trp-Trp	Bacterial	Infection
H-Trp-Trp-Trp-OH (Trp-Trp-Trp) is a tripeptide consisting of tryptophan. H-Trp-Trp-Trp-OH has antibacterial activity. H-Trp-Trp-Trp-OH is a human bitter taste receptor hTAS2R14 agonist .

HY-P2081

Delicious peptide	Peptides	Others
Delicious peptide is a small linear octapeptide with delicious taste, can be isolated from the gravy of beef meat. Delicious peptide has savory flavor, is also described as beefy meaty peptide and a beef flavor enhancer .

HY-P4450

Homoglutathione γ-Glu-Cys-β-Ala; H-γ-Glu-Cys-β-Ala-OH	Peptides	Others
Homoglutathione is a ubiquitous and indispensable tripeptide in eukaryotes with multi-facetted functions, many of which relate to cellular redox regulation. Homoglutathione has taste modifying effect .

HY-P4600

H-Ala-Arg-OH	Peptides	Others
H-Ala-Arg-OH is an L-arginyl dipeptide that can be used as salt taste enhancer .

HY-100047R

Nα,Nα-Bis(carboxymethyl)-L-lysine (Standard)	Taste Receptor Reference Standards	Others
Nα,Nα-Bis(carboxymethyl)-L-lysine (Standard) is the analytical standard of Nα,Nα-Bis(carboxymethyl)-L-lysine (HY-100047). This product is intended for research and analytical applications. Nα,Nα-Bis(carboxymethyl)-L-lysine is a competitive inhibitor of bitter taste receptor 4, with an IC50 of 59 nM. Nα,Nα-Bis(carboxymethyl)-L-lysine can be used in bitter receptors related study .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-41417

Octanoic acid 3 Publications Verification Caprylic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Endogenous Metabolite
Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes. Octanoic acid is also a tremor-suppressing agent .

HY-Y1069

(S)-Malic acid 2 Publications Verification (S)-Hydroxybutanedioic acid; (S)-E 296; L-Malic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
(S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive.

HY-N0466

Rebaudioside A	Structural Classification Classification of Application Fields Plants Compositae Endogenous metabolite Sweeteners Food Research Trifolium hybridum L. Terpenoids Other Diseases Diterpenoids Disease Research Fields Source Classification	Glycosidase HMG-CoA Reductase (HMGCR) Fatty Acid Synthase (FASN) LDLR
Rebaudioside A is an orally effective steviol glycoside with high sweetness. Rebaudioside A acts as an inhibitor of α-glucosidase with an IC₅₀ value of 35.01 μg/mL. Rebaudioside A increases the ATP/ADP ratio in β cells in a glucose-dependent manner, thereby inhibiting KATP channels, leading to membrane depolarization, calcium influx, and ultimately stimulating insulin secretion. Rebaudioside A activates the SREBP signaling pathway by inhibiting HMGCR, the rate-limiting enzyme in cholesterol synthesis, resulting in increased expression of LDLR on the cell surface, thus promoting the uptake of LDL-C in the blood. Rebaudioside A can be used for studies on blood glucose and lipid regulation as well as anti-obesity .

HY-W007035

H-Val-Ala-OH 1 Publications Verification Valyl-alanine	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Amino Acid Derivatives
H-Val-Ala-OH (Valyl-alanine) is a dipeptide formed from L-Valine and L-Alanine residues. H-Val-Ala-OH has a role as a metabolite and also has a bitter taste .

HY-139338

Erlose 1 Publications Verification	Structural Classification Polysaccharides Animals Classification of Application Fields Other Diseases Disease Research Fields Sweeteners Saccharides Source Classification Food Research	Glycosidase
Erlose is a trisaccharide sucrose derivative and low-calorie sweetener synthesized from glucose and sucrose via an α-glucosidase-mediated transglycosylation reaction. Erlose is often used as a marker to identify whether honey is adulterated with artificial sucrose. Erlose has approximately half the sweetness of sucrose but a similar taste, and it effectively inhibits crystal formation and browning reactions during food heat treatment .

HY-W010607

cis-3-Hexen-1-ol (Z)-3-Hexen-1-ol	Structural Classification Natural Products Neurological Disease Classification of Application Fields Leguminosae Plants Phaseolus vulgaris Linn. Disease Research Fields Source Classification Food Research	Environmental Pollutants
cis-3-Hexen-1-ol ((Z)-3-Hexen-1-ol) is a green grassy smelling compound found in many fresh fruits and vegetables with bitter taste enhancement. cis-3-Hexen-1-ol is widely used as an added flavor in processed food to provide a fresh green quality. cis-3-Hexen-1-ol is an attractant to various insects .

HY-N0467

Rebaudioside C Dulcoside B	Trifolium hybridum L. Classification of Application Fields Terpenoids Other Diseases Diterpenoids Plants Compositae Endogenous metabolite Disease Research Fields Sweeteners Source Classification Food Research	Endogenous Metabolite
Rebaudioside C (Dulcoside B) is an orally effective natural sweetener that cannot pass the blood-brain barrier and selectively binds to human sweet taste receptors (TAS1R2/TAS1R3). The sweetness of Rebaudioside C is about 20-30 times that of sucrose, and its sweetness activity depends on the C-16/C-17 double bond structure and specific aglycones. The glycoside structure in the Rebaudioside C molecule can bind to the sweet taste receptor, activate the taste signal transduction pathway, and produce sweetness perception .

HY-D0887

Disodium 5'-inosinate 1 Publications Verification IMP disodium salt; Disodium inosinate	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Disease Research Fields Source Classification Food Research	Others
Disodium 5'-inosinate (IMP disodium salt) is a nucleotide-based umami agent. Disodium 5'-inosinate can bind to umami receptors and stimulate taste nerves, allowing the brain to perceive umami. In addition, Disodium 5'-inosinate produces a transient behavioral excitement in mice .

HY-111664

(R)-(+)-Citronellal (+)-Citronellal	Structural Classification Other Monoterpenes Classification of Application Fields Terpenoids Citrus limon (L.) Burm. F. Rutaceae Metabolic Disease Plants Endogenous metabolite Disease Research Fields Citrus reticulata Blanco Source Classification	Bacterial Fungal Insecticide Taste Receptor Opioid Receptor
(R)-(+)-Citronellal ((+)-Citronellal) is a monoterpenoid compound and is one of the main components of essential oils from plants such as lemon grass. (R)-(+)-Citronellal has antibacterial, antifungal, and insecticidal activities. (R)-(+)-Citronellal alleviates the bitterness of caffeine by antagonizing the bitter taste receptors Tas2r43 (IC₅₀ = 84 μM) and Tas2R46. (R)-(+)-Citronellal generates analgesic activity by activating the opioid receptor (broad-spectrum opioid receptor) pathway, and its effect is particularly significant for inflammatory pain .

HY-N10319

Artepillin C	Ketones, Aldehydes, Acids Plants Compositae Artemisia capillaris Thunb. Source Classification	Epigenetic Reader Domain Necroptosis TRP Channel
Artepillin C is an orally active CREB/CRTC2 inhibitor and TRPA1 covalent agonist (EC₅₀=1.8 μM). Artepillin C inhibits CREB/CRTC2-mediated gene transcription and downregulates BMAL1 expression to regulate glucose and lipid metabolism. Artepillin C can also activate TRPA1 channels to induce spicy taste signals. Artepillin C can inhibit tumor cell proliferation, induce necroptosis, improve insulin resistance and inhibit liver lipid synthesis. Artepillin C can be used in the study of metabolic syndrome, tumor prevention and treatment, and inflammation .

HY-N2084

Perillartine 2 Publications Verification DL-Perillartine	Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Sweeteners Source Classification Food Research	Endogenous Metabolite
Perillartine is a sweetener, which activates the taste receptor type 1 member 2 (Tas1r2) subunit in a species-dependent manner.

HY-N6808

Rebaudioside B	Trifolium hybridum L. other families Classification of Application Fields Terpenoids Other Diseases Diterpenoids Plants Compositae Disease Research Fields Source Classification	Others
Rebaudioside B is the minor constituent isolated from the leaves of Stevia rebaudiana Bertoni. Rebaudioside B tastes about 150 times sweeter than sucrose. Rebaudioside B can hydrolysis to steviol .

HY-N0917

6''-O-Malonylgenistin 1 Publications Verification Malonylgenistin; Genistin malonate	Flavonoids Classification of Application Fields Leguminosae Glycine max (L.) merr Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Isoflavones Source Classification	Drug Metabolite Taste Receptor
6''-O-Malonylgenistin (Malonylgenistin) is a glycosylated isoflavone and metabolite of Genistin (HY-N0595). 6''-O-Malonylgenistin activates hTAS2R39. 6''-O-Malonylgenistin can be used in the research of bitter taste .

HY-N6992

Dulcoside A	other families Classification of Application Fields Terpenoids Metabolic Disease Diterpenoids Plants Disease Research Fields Sweeteners Source Classification Food Research	Taste Receptor
Dulcoside A is a glycoside that can be isolated from Stevia rebaudiana that elicits sweet and bitter taste through activation of TAS1R. Dulcoside A also exhibits anti-inflammatory activity .

HY-N8210

Homoeriodictyol	Flavonoids other families Classification of Application Fields Flavonones Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Drug Metabolite Autophagy Apoptosis Reactive Oxygen Species (ROS) Keap1-Nrf2 MMP Caspase PARP MDM-2/p53
Homoeriodictyol is an orally active, bitter-tasting flavanone that can penetrate the blood-brain barrier. Homoeriodictyol enhances synaptic-related protein expression through NCOA4-mediated ferritin autophagy. Homoeriodictyol improves memory impairment in mice by inhibiting the NLRP3 inflammasome. Homoeriodictyol protects human endothelial cells from oxidative damage by activating Nrf2 and inhibiting mitochondrial dysfunction. Homoeriodictyol enhances ROS activity and induces apoptosis, exhibiting anticancer effects. Homoeriodictyol inhibits the survival and migration of androgen-resistant prostate cancer cells in vitro. Homoeriodictyol exerts antinociceptive activity in mice in vivo .

HY-N0742

Absinthin	Triterpenes Classification of Application Fields Terpenoids Other Diseases Plants Acacia confusa Merr. Compositae Disease Research Fields Source Classification	Others
Absinthin is a structurally unique triterpene, and is responsible for the high bitter value of wormwood. Absinthin is an agonist of the bitter taste receptor hTAS2R46, which reduces cytosolic Ca ²⁺-rises induced by histamine by a receptor-specific mechanism mediated by hTAS2R46 .

HY-41417R

Octanoic acid (Standard) 3 Publications Verification Caprylic acid (Standard)	Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Endocrine diseases Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Reference Standards Endogenous Metabolite
Octanoic acid (Standard) is the analytical standard of Octanoic acid. This product is intended for research and analytical applications. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.

HY-N7438

Mogroside VI A	Triterpenes Classification of Application Fields Terpenoids Cucurbitaceae Other Diseases Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Disease Research Fields Sweeteners Source Classification Food Research	Others
Mogroside VI A, an isomer of Mogroside VI isolated from Luo Han Guo, exerts sweetness property. Mogroside VI A can be used for sweetener and/or taste modifier research .

HY-Y1069R

(S)-Malic acid (Standard) 1 Publications Verification (S)-Hydroxybutanedioic acid (Standard); (S)-E 296 (Standard); L-Malic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
(S)-Malic acid (Standard) is the analytical standard of (S)-Malic acid (HY-Y1069). This product is intended for research and analytical applications. (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive.

HY-N10319R

Artepillin C (Standard)	Ketones, Aldehydes, Acids Plants Compositae Artemisia capillaris Thunb. Source Classification	Reference Standards TRP Channel Necroptosis Epigenetic Reader Domain
Artepillin C (Standard) is the analytical standard of Artepillin C (HY-N10319). This product is intended for research and analytical applications. Artepillin C is an orally active CREB/CRTC2 inhibitor and TRPA1 covalent agonist (EC₅₀=1.8 μM). Artepillin C inhibits CREB/CRTC2-mediated gene transcription and downregulates BMAL1 expression to regulate glucose and lipid metabolism. Artepillin C can also activate TRPA1 channels to induce spicy taste signals. Artepillin C can inhibit tumor cell proliferation, induce apoptosis, improve insulin resistance and inhibit liver lipid synthesis. Artepillin C can be used in the study of metabolic syndrome, tumor prevention and treatment, and inflammation .

HY-W016979

δ-Decalactone	Structural Classification Natural Products Classification of Application Fields Rosaceae Other Diseases Plants Disease Research Fields Amygdalus persica L. Source Classification	Environmental Pollutants
δ-Decalactone is a lactone compound found in nonfat dry milks and fruit. δ-Decalactone has a sweet taste .

HY-W007035R

H-Val-Ala-OH (Standard) Valyl-alanine (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Amino Acid Derivatives
H-Val-Ala-OH (Valyl-alanine) is a dipeptide formed from L-Valine and L-Alanine residues. H-Val-Ala-OH has a role as a metabolite and also has a bitter taste .

HY-W017562

γ-Octalactone	Carica papaya L. Structural Classification Ketones, Aldehydes, Acids Caricaceae Plants Source Classification	Environmental Pollutants Biochemical Assay Reagents
γ-Octalactone is an aromatic lactone compound. γ-Octalactone has a strong fruity (similar to coconut) aroma and a sweet taste, and is commonly used in food, cosmetics and fragrances. γ-Octalactone is highly safe .

HY-W016979R

δ-Decalactone (Standard)	Structural Classification Natural Products Microorganisms Rosaceae Plants Amygdalus persica L. Source Classification	Reference Standards Others
δ-Decalactone (Standard) is the analytical standard of δ-Decalactone. This product is intended for research and analytical applications. δ-Decalactone is a lactone compound found in nonfat dry milks and fruit. δ-Decalactone has a sweet taste .

HY-N6992R

Dulcoside A (Standard)	other families Terpenoids Diterpenoids Plants Source Classification	Reference Standards Taste Receptor
Dulcoside A (Standard) is the analytical standard of Dulcoside A. This product is intended for research and analytical applications. Dulcoside A is a glycoside that can be isolated from Stevia rebaudiana that elicits sweet and bitter taste through activation of TAS1R. Dulcoside A also exhibits anti-inflammatory activity .

HY-N11976

Glycyrrhizin-6′′-methylester	Glycyrrhiza glabra Linn. Leguminosae Ketones, Aldehydes, Acids Plants Source Classification	Others
Glycyrrhizin-6′′-methylester (compound 22) is a glycyrrhizin that can be isolated from licorice root. Glycyrrhizin-6′′-methylester can participate as an aglycone in the formation of methyl glucuronate, producing a sweet and licorice taste, but no bitterness. This reveals the importance of the free carboxyl group on the glycoside cone-bound glucuronic acid for natural sweetness and licorice taste .

HY-N2084R

Perillartine (Standard) DL-Perillartine (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Perillartine is a sweetener, which activates the taste receptor type 1 member 2 (Tas1r2) subunit in a species-dependent manner.

HY-W178699

(±)-Neoisomenthol	Structural Classification Other Monoterpenes Philadelphus coronarius L. Terpenoids Hydrangeaceae Plants Source Classification	Drug Derivative
(±)-Neoisomenthol is a monoterpene. (±)-Neoisomenthol is a volatile constituent of Mentha arvensis with a peppermint odor and taste. (±)-Neoisomenthol is a chiral compound, existing as a racemic mixture of two enantiomers, (+)-Neoisomenthol and (-)-Neoisomenthol .

HY-Y0418R

Dulcite (Standard) Dulcitol (Standard); Melampyrit (Standard); NSC 1944 (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Animals Endogenous metabolite Saccharides Source Classification	Reference Standards Endogenous Metabolite
Dulcite (Standard) is the analytical standard of Dulcite. This product is intended for research and analytical applications. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galactose.

HY-N6808R

Rebaudioside B (Standard)	Structural Classification Trifolium hybridum L. other families Terpenoids Diterpenoids Plants Compositae Source Classification	Reference Standards Others
Rebaudioside B (Standard) is the analytical standard of Rebaudioside B. This product is intended for research and analytical applications. Rebaudioside B is the minor constituent isolated from the leaves of Stevia rebaudiana Bertoni. Rebaudioside B tastes about 150 times sweeter than sucrose .

HY-N1516A

(Z)-Ganoderenic acid D	Triterpenes Microorganisms Terpenoids Source Classification	Apoptosis
(Z)-Ganoderenic acid D is the z-isomer of Ganoderenic acid D (HY-N1516). (Z)-Ganoderenic acid D is the triterpene that can be isolated from Ganoderma, and contributes to the bitter taste of the basidiocarps and extracts of Ganoderma species. Ganoderenic acid D inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis .

HY-N8210R

Homoeriodictyol (Standard)	Structural Classification Flavonoids other families Flavonones Phenols Polyphenols Plants Source Classification	Reference Standards Drug Metabolite Autophagy Apoptosis Reactive Oxygen Species (ROS) Keap1-Nrf2 MMP Caspase PARP MDM-2/p53
Homoeriodictyol (Standard) is the analytical standard of Homoeriodictyol (HY-N8210). This product is intended for research and analytical applications. Homoeriodictyol is an orally active, bitter-tasting flavanone that can penetrate the blood-brain barrier. Homoeriodictyol enhances synaptic-related protein expression through NCOA4-mediated ferritin autophagy. Homoeriodictyol improves memory impairment in mice by inhibiting the NLRP3 inflammasome. Homoeriodictyol protects human endothelial cells from oxidative damage by activating Nrf2 and inhibiting mitochondrial dysfunction. Homoeriodictyol enhances ROS activity and induces apoptosis, exhibiting anticancer effects. Homoeriodictyol inhibits the survival and migration of androgen-resistant prostate cancer cells in vitro. Homoeriodictyol exerts antinociceptive activity in mice in vivo .

HY-N18017

Shinjuglycoside C	Triterpenes Structural Classification Simaroubaceae Ailanthus altissima (Mill.) Swingle Terpenoids Plants Source Classification	Drug Derivative
Shinjuglycoside C (Compound 3) is a quassinoid glycoside that can be isolated from the seeds of Ailanthus altissima. Shinjuglycoside C exhibits a bitter taste .

HY-N13797

1,6,2',6'-O-Tetraacetyl-3-O-trans-p-coumaroylsucrose	Structural Classification Monophenols Rosaceae Phenols Plants Prunus jamasakura (Siebold ex Koidz.) X.R.Wang & C.B.Shang Source Classification	Drug Derivative
1,6,2',6'-O-Tetraacetyl-3-O-trans-p-coumaroylsucrose (Compound 12) is a bitter-tasting compound present in the drupes of Prunus maximowiczii .

HY-W726468

Feruloylaspartic acid	Malvaceae Structural Classification Monophenols Theobroma cacaoL. Phenols Plants Source Classification	Others
Feruloylaspartic acid (Compound 19) is an N-cinnamoyl-L-amino acid, and it is a key astringent compound responsible for the puckering sensation in roasted cocoa beans. Feruloylaspartic acid elicits a puckering, astringent oral sensation without exhibiting a bitter taste .

HY-N18688

Gymnema sylvestre extract	Structural Classification Extract	Others
Gymnema sylvestre extract, derived from the leaves of the Gymnema sylvestre plant, is renowned for its anti-diabetic and blood sugar-regulating properties. The key active compounds in the extract are gymnemic acids, which are responsible for its ability to block the taste of sweetness and reduce sugar absorption in the intestines.

HY-N19793

Derrisaponin B	Triterpenes Structural Classification Leguminosae Terpenoids Brachypterum eriocarpum (F. C. How) Adema & Sirich. Plants Source Classification	Drug Derivative
Derrisaponin B is an oleanane-type triterpenoid saponin and sweetener found in the stems of Derris eriocarpa How, with sweetness intensity approximately 2 times that of Sucrose (HY-B1779) at 1% concentration. Derrisaponin B exhibits sweet taste activity. Derrisaponin B can be used for research on hypertension, hyperglycemia, and obesity .

HY-N15634

Anticopalic acid	Structural Classification Ketones, Aldehydes, Acids Labiatae Petasites hybridus (L.) G.Gaertn., B.Mey. & Schreb. Plants Source Classification	Insecticide
Anticopalic acid is a labdane-type diterpenoid insect antifeedant that exhibits dose-dependent antifeedant activity against the fall armyworm (Spodoptera frugiperda). Anticopalic acid can be isolated from Vitex hemsleyi. Anticopalic acid may be involved in neuroreceptor-mediated insect taste regulation and could be used to develop environmentally friendly antifeedants targeting lepidopteran pests .

HY-N9752

Mogroside II B	Structural Classification Cucurbitaceae Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Steroids Source Classification	EBV
Mogroside II B is a cucurbitane-type glycoside with a sweet taste in water. Mogroside II B inhibits the activation of Epstein Barr virus early antigen (EBV-EA) induced by Phorbol 12-myristate 13-acetate (TPA) (HY-18739). Mogroside II B exerts weak inhibitory effects on the activation of the nitric oxide (NO) donor (NOR1) .

HY-N0742R

Absinthin (Standard)	Triterpenes Structural Classification Terpenoids Plants Acacia confusa Merr. Compositae Source Classification	Reference Standards Others
Absinthin (Standard) is the analytical standard of Absinthin. This product is intended for research and analytical applications. Absinthin is a structurally unique triterpene, and is responsible for the high bitter value of wormwood. Absinthin is an agonist of the bitter taste receptor hTAS2R46, which reduces cytosolic Ca2+-rises induced by histamine by a receptor-specific mechanism mediated by hTAS2R46 .

HY-N12639

β-Sanshool	Zanthoxylum bungeanum Maxim. Structural Classification Natural Products Rutaceae Plants Source Classification	TRP Channel
β-Sanshool is found in Zanthoxylum bungeanum and has a unique pungent taste. β-Sanshool is a TRPV1 activator that activates TRPV1 to increase intracellular calcium concentration. β-Sanshool has antioxidant effects and enhances free radical scavenging activity. β-Sanshool increases the thermal denaturation temperature and stabilizes protein structures. β-Sanshool induces sensory experiences of numbness and bitterness .

Cat. No.	Product Name	Chemical Structure

HY-41417S4

Octanoic acid-13C4
Octanoic acid- ¹³C₄ is the ¹³C labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.

HY-Y1069S

(S)-Malic acid-d3 1 Publications Verification
(S)-Malic acid-d₃ is the deuterium labeled (S)-Malic acid. (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive .

HY-41417S3

Octanoic acid-13C
Octanoic acid- ¹³C is the ¹³C labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.

HY-41417S

Octanoic acid-d15
Octanoic acid-d₁₅ is the deuterium labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.

HY-41417S1

Octanoic acid-d3
Octanoic acid-d₃ is the deuterium labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.

HY-W724355

Denatonium benzoate-d5

Denatonium benzoate-d₅ (THS-839-d₅) is the deuterium labeled Denatonium benzoate (HY-B1146). Denatonium benzoate (THS-839) is known as the most bitter compound and is commonly used as a deterrent (bittering agent) to activate different types of bitter taste receptors (TAS2Rs) with oral activity. Denatonium benzoate can enhance insulin secretion, has anti-inflammatory effects, and promotes allergy susceptibility .

HY-Y0418S4

Dulcite-d2
Dulcite-d₂ is the deuterium labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact .

HY-Y0418S

Dulcite-13C
Dulcite- ¹³C is the ¹³C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact .

HY-Y0418S3

Dulcite-13C-3
Dulcite- ¹³C-3 is the ¹³C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact .

HY-Y0418S1

Dulcite-13C-1
Dulcite- ¹³C-1 is the ¹³C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact .

HY-Y0418S2

Dulcite-13C-2
Dulcite- ¹³C-2 is the ¹³C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact .

HY-41417S6

Octanoic acid-d5
Octanoic acid-d₅ is the deuterium labeled Octanoic acid . Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.

HY-W017562S

γ-Octalactone-d7
γ-Octalactone-d₇ is deuterated labeled γ-Octalactone (HY-W017562). γ-Octalactone is an aromatic lactone compound. γ-Octalactone has a strong fruity (similar to coconut) aroma and a sweet taste, and is commonly used in food, cosmetics and fragrances. γ-Octalactone is highly safe.

HY-W007035S

H-Val-Ala-OH-13C5,15N TFA
H-Val-Ala-OH- ¹³C₅, ¹⁵N (Valyl-alanine- ¹³C₅, ¹⁵N) TFA is the ¹³C- and ¹⁵N-labeled H-Val-Ala-OH (HY-W007035). H-Val-Ala-OH (Valyl-alanine) is a dipeptide formed from L-Valine and L-Alanine residues. H-Val-Ala-OH has a role as a metabolite and also has a bitter taste .

HY-41417S2

Octanoic acid-d2
Octanoic acid-d₂ is the deuterium labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.

Cat. No.	Product Name		Classification

HY-41417

Octanoic acid 3 Publications Verification Caprylic acid		Preservatives
Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes. Octanoic acid is also a tremor-suppressing agent .

HY-Y1069

(S)-Malic acid 2 Publications Verification (S)-Hydroxybutanedioic acid; (S)-E 296; L-Malic acid		Flavoring Agents
(S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive.

HY-W015339

Octanoate, 99% sodium 3 Publications Verification		Preservatives
Octanoate, 99% sodium is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes. Octanoate, 99% sodium is also an orally active tremor-suppressing agent .

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