SIRT1 activator 2
Based on 1 Customer Validation
SIRT1 activator 2 is a SIRT1 activator with an ED50 value <5 μM. SIRT1 activator 2 modulates SIRT1 deacetylase activity. SIRT1 activator 2 can be used for aging research.
For research use only. We do not sell to patients.
- Purity: 99.28%
- CAS No.: 863589-52-0
- Formula: C20H15N3O2S
- Molecular Weight:361.42
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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SIRT1 <5 μM (ED50) |
SIRT1 activator 2 (compound 212) exhibits an ED50 <5 μM and fold activation <250% to SIRT1 protein in the mass spectrometry based assay[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 863589-52-0
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Appearance Solid
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Molecular Weight 361.42
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Formula C20H15N3O2S
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Color White to off-white
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SMILES
O=C(C1=CC(OC)=CC=C1)NC2=CC=CC(C3=NC4=CC=CN=C4S3)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 5 mg/mL (13.83 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.7669 mL | 13.8343 mL | 27.6686 mL | 69.1716 mL |
| 5 mM | 0.5534 mL | 2.7669 mL | 5.5337 mL | 13.8343 mL | |
| 10 mM | 0.2767 mL | 1.3834 mL | 2.7669 mL | 6.9172 mL |
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