1. Epigenetics
  2. Histone Methyltransferase
  3. BIX-01338 hydrate

BIX-01338 hydrate is a histone lysine methyltransferase inhibitor.

For research use only. We do not sell to patients.

BIX-01338 hydrate Chemical Structure

BIX-01338 hydrate Chemical Structure

CAS No. : 1228184-65-3

Size Price Stock Quantity
5 mg USD 500 In-stock
10 mg USD 850 In-stock
25 mg USD 1800 In-stock
50 mg USD 3000 In-stock
100 mg USD 4600 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

BIX-01338 hydrate is a histone lysine methyltransferase inhibitor.

IC50 & Target

Histone lysine methyltransferase[1]

Molecular Weight

621.56

Formula

C32H26F3N3O7

CAS No.
Appearance

Solid

Color

Light blue to blue

SMILES

O=C(C1=CC=C2C(N=C(NC(C3=CC=C(C(F)(F)F)C=C3)=O)N2CCC4=CC=C(OC(C5=CC=C(OC)C=C5)=O)C=C4)=C1)O.O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (321.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6089 mL 8.0443 mL 16.0886 mL
5 mM 0.3218 mL 1.6089 mL 3.2177 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6089 mL 8.0443 mL 16.0886 mL 40.2214 mL
5 mM 0.3218 mL 1.6089 mL 3.2177 mL 8.0443 mL
10 mM 0.1609 mL 0.8044 mL 1.6089 mL 4.0221 mL
15 mM 0.1073 mL 0.5363 mL 1.0726 mL 2.6814 mL
20 mM 0.0804 mL 0.4022 mL 0.8044 mL 2.0111 mL
25 mM 0.0644 mL 0.3218 mL 0.6435 mL 1.6089 mL
30 mM 0.0536 mL 0.2681 mL 0.5363 mL 1.3407 mL
40 mM 0.0402 mL 0.2011 mL 0.4022 mL 1.0055 mL
50 mM 0.0322 mL 0.1609 mL 0.3218 mL 0.8044 mL
60 mM 0.0268 mL 0.1341 mL 0.2681 mL 0.6704 mL
80 mM 0.0201 mL 0.1006 mL 0.2011 mL 0.5028 mL
100 mM 0.0161 mL 0.0804 mL 0.1609 mL 0.4022 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

BIX-01338 hydrate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
BIX-01338 hydrate
Cat. No.:
HY-12991A
Quantity:
MCE Japan Authorized Agent: