Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2569)
Related Products (2569)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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Aspyrone
0 ImagesCat. No.: HY-121003CAS No.: 17398-00-4Aspyrone is a polyketide fungal metabolite that has been found in Aspergillus and has diverse biological activities. It is active against a panel of 13 fungi when used at a concentration of 20 μg/mL and a panel of 21 bacteria in a disc assay when used at a concentration of 100 μg per disc.1 Aspyrone (10-1,000 mg/L) is nematocidal against P. penetrans.
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LASSBio-1736
0 ImagesCat. No.: HY-184205CAS No.: 1554691-37-0LASSBio-1736 is a Cysteine protease inhibitor and antimalarial agent. LASSBio-1736 targets the promastigote form of Leishmania major. LASSBio-1736 can be used in the research of leishmaniasis.
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Azadirone
0 ImagesCat. No.: HY-121200CAS No.: 25279-67-8Azadirone sensitized cancer cells to TNF-related apoptosis-inducing ligand (TRAIL) through ROS-ERK-CHOP-mediated up-regulation of DR5 and DR4 expression, down-regulation of cell survival proteins, and up-regulation of proapoptotic proteins (Bid). Azadirone has antiplasmodial activity.
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Antileishmanial agent-30
0 ImagesCat. No.: HY-162833Antileishmanial agent-30 (compound 17k) is a potent inhibitor of leishmania, with the IC50, CC50, and SI of 0.2 μM, >100 μM and >500 for L. donovani.
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Z-Antiepilepsirine
0 ImagesCat. No.: HY-N11031CAS No.: 111479-04-0Z-Antiepilepsirine is an amide alkaloid that can be found in Piper capense L.f. Z-Antiepilepsirine shows antiplasmodial activity with an IC50 value of 27 µM for W2 strain of Plasmodium falciparum.
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Betulonaldehyde
0 ImagesBetulonaldehyde is a pentacyclic triterpenoid that can be isolated from Diospyros filipendula. Betulonaldehyde has antiplasmodial activity (IC50: 3.36 µg/mL). Betulonaldehyde has cytotoxic to NCI H187 lung cancer cells and non-cancerous Vero cells (IC50s: 19.23 and 17.09 µg/mL, respectively). Betulonaldehyde inhibits Phorbol 12-myristate 13-acetate (HY-18739) induced inflammation in mice.
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Fenazaquin-d13
0 ImagesCat. No.: HY-W739267Synonyms: XDE-436-d13; EL-436-d13Fenazaquin-d13 (XDE-436-d13) is the deuterium labeled Fenazaquin (HY-117397). Fenazaquin (XDE-436; EL-436) is a quinazoline acaricide.
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Oltipraz (GMP)
0 ImagesCat. No.: HY-12519GCAS No.: 64224-21-1Synonyms: RP 35972 (GMP); NSC 347901 (GMP)
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Myricitrin (Standard)
0 ImagesMyricitrin (Standard) is the analytical standard of Myricitrin. This product is intended for research and analytical applications. Myricitrin, a naturally occurring flavonoid, is an orally active nitric oxide (NO) and PKC inhibitor. Myricitrin has central nervous system activity, including anxiolytic-like action. Myricitrin possesses antioxidant, anti-inflammatory, antifibrotic and anti-malarial effects.
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KAI-407
0 ImagesCat. No.: HY-18746CAS No.: 1513879-18-9KAI-407 is an orally active inhibitor of Plasmodium PI4K kinase, which can broadly inhibit multiple stages of the parasite lifecycle. KAI-407 exhibits EC50s of for the blood stage of malignant Plasmodium of 81 nM; for the liver schizonts of P. yoelii of 88 nM; and IC50s for the liver schizonts and dormant bodies of P. cynomolgi of 0.64 μM and 0.69 μM respectively. KAI-407 can prevent Plasmodium berghei infection 100%. KAI-407 can be used for the study of vivax malaria.
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Hexamidine-d12
0 ImagesCat. No.: HY-W740485CAS No.: 1286461-12-8Hexamidine-d12 is the deuterium labeled Hexamidine. Hexamidine has amoebicidal effect that can be used for the research of Acanthamoeba keratitis.
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MMV665916
0 ImagesCat. No.: HY-W026467CAS No.: 896356-25-5MMV665916, a quinazolinedione derivative, is an antimalarial agent. MMV665916 displays antiplasmodial activity against P. falciparum FcB1 strain with EC50 value of 0.4 μM and presents the high selectivity index (SI>250).
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Amphotericin B trihydrate
0 ImagesCat. No.: HY-B0221ACAS No.: 1202017-46-6Amphotericin B trihydrate, a polyene antibiotic, is first isolated from fermenter cultures of Streptomyces nodosus. Amphotericin B trihydrate also possesses antileishmanial activity.
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Antitrypanosomal agent 15
0 ImagesCat. No.: HY-155103CAS No.: 2961381-94-0Antitrypanosomal agent 15 (compound 26) is an orally active, brain-penetrant, selective inhibitor against Trypanosoma cruzi proteasome, with an pIC50 of 7.4 and <4 for T. cruzi and human proteasome, respectively. Antitrypanosomal agent 15 has favorable ADME properties and can be used for Chagas disease study.
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Ethopabate-d5
0 ImagesCat. No.: HY-W702966CAS No.: 2469244-16-2Synonyms: Ethyl pabate-d5Ethopabate-d5 (Ethyl pabate-d5) is the deuterium labeled Ethopabate (HY-B2138). Ethopabate (Ethyl pabate) is an orally active antiparasitic agent. Ethopabate is often used in combination with Amprolium hydrochloride (HY-B0937A) and others to prevent and treat poultry coccidiosis, leucosis, and other diseases.
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(R)-Hydroxychloroquine phosphate
0 ImagesCat. No.: HY-B1370ECAS No.: 2488706-20-1Synonyms: (R)-HCQ phosphate(R)-Hydroxychloroquine ((R)-HCQ) phosphate is a (R)-isomer of Hydroxychloroquine (HY-W031727). (R)-Hydroxychloroquine inhibits the insulin metabolizing enzyme of cytosolic fraction of liver homogenates in healthy and diabetic rats.
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α-Artemether
0 ImagesCat. No.: HY-137217CAS No.: 71939-51-0Synonyms: Methoxyα-Artemether is an antimalarial compound.
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8-Acetonyldihydrochelerythrine
0 ImagesCat. No.: HY-N18179CAS No.: 15575-49-28-Acetonylidihydrochelerythrine is a benzophenanthridine alkaloid found in the stem bark of Zanthoxylum gilletii. 8-Acetonylidihydrochelerythrine inhibits growth of Chloroquine (HY-17589A)-resistant and Chloroquine-sensitive Plasmodium falciparum strains. 8-Acetonylidihydrochelerythrine can be used for the research of malaria.
