Prostaglandin Receptor
Prostaglandin receptor, a sub-family of cell surface seven-transmembrane receptors, are the G-protein-coupled receptors. There are currently ten known prostaglandin receptors on various cell types. Prostaglandins bind to a subfamily of cell surface seven-transmembrane receptors, G-protein-coupled receptors. These receptors are named: DP1-2-DP1, DP2 receptors, EP1-4-EP1, EP2, EP3, EP4 receptors, FP-FP, IP1-2-IP1, IP2 receptors, TP-TP receptor. The prostaglandins are a group of hormone-like lipid compounds that are derived enzymatically from fatty acids and have important functions in the animalbody. There are currently ten known prostaglandin receptors on various cell types.
Prostaglandin Receptor Isoform Specific Products
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Prostaglandin Receptor Inhibitors
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Prostaglandin Receptor Agonists
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Prostaglandin Receptor Antagonists
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Prostaglandin Receptor Activators
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Prostaglandin Receptor Modulators
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Prostaglandin Receptor Inducers
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Prostaglandin Receptor Degrader
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Prostaglandin Receptor Controls
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Prostaglandin Receptor Ligands
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Prostaglandin Receptor Related Products (766)
Related Products (766)
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Antibodies (2)
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Prostaglandin Receptor Isoform Comparison
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8-iso Prostaglandin E1
0 ImagesCat. No.: HY-118094CAS No.: 21003-46-3Synonyms: Ovinonic acid; 8-iso-PGE18-iso Prostaglandin E1 (Ovinonic acid; 8-iso-PGE1) is a spasmodic agent in canine pulmonary veins and can also cause vasodilation.
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Ciprostene calcium
0 ImagesCat. No.: HY-122499CAS No.: 81703-55-1Ciprostene calcium is a prostacyclin analogue.Ciprostene calcium inhibits adenosine diphosphate-induced platelet aggregation. Ciprostene calcium can be used for research of peripheral vascular disease.
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BGC-20-1531 hydrochloride
0 ImagesCat. No.: HY-110351CAS No.: 1962928-26-2Synonyms: PGN 1531 hydrochloride
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PF-04475270
0 ImagesCat. No.: HY-185643CAS No.: 1201925-19-0PF-04475270 is a prodrug of CP-734432 (HY-119236), as well as an agonist of the EP4 prostaglandin receptor, with IC50 values of 2 nM and 8 nM against human and canine sources, respectively. PF-04475270 is rapidly hydrolyzed into its active metabolite CP-734432 by ocular esterases or corneal homogenate, stimulates cAMP production, and activates cAMP response element-mediated β-lactamase activity in cells expressing EP4. PF-04475270 can be used in research related to glaucoma.
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AGN192093
0 ImagesCat. No.: HY-123613CAS No.: 159359-95-2AGN192093 is a thromboxane A2 receptor (TP) agonist (EC50 = 1.3 nM). AGN192093 exhibits potent and selective thromboxane analog activity in rat blood vessels.
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AL-3138
0 ImagesCat. No.: HY-125150CAS No.: 64603-03-8Synonyms: 11-Deoxy-16-fluoro PGF2α
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Tranilast (Standard)
0 ImagesSynonyms: MK-341 (Standard); SB 252218 (Standard)Tranilast (Standard) is the analytical standard of Tranilast. This product is intended for research and analytical applications. Tranilast (MK-341) acts as an anti-atopic agent. Tranilast suppresses production of prostaglandin D2 (PGD2, IC50= 0.1 mM). Tranilast sodium exhibits anti-inflammatory and immunomodulatory effects. Tranilast sodium antagonizes angiotensin II and inhibits its biological effects in vascular smooth muscle cells.
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Latanoprost amide
0 ImagesCat. No.: HY-156101CAS No.: 919281-21-3Latanoprost amide is a derivative of the F-prostaglandin (FP) receptor agonist Latanoprost (HY-B0577).
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17-Phenyl trinor prostaglandin F2α glycinamide methyl ester
0 ImagesCat. No.: HY-176011Synonyms: 17-Phenyl trinor PGF2α glycinamide methyl ester17-Phenyl trinor prostaglandin F2α glycinamide methyl ester is a derivative of Bimatoprost (HY-B0191) and a prostaglandin analog. 17-Phenyl trinor prostaglandin F2α glycinamide methyl ester is a human prostaglandin FP receptor agonist. 17-Phenyl trinor prostaglandin F2α glycinamide methyl ester has an ocular hypotensive effect and can be used in the study of ocular hypertension and glaucoma.
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8-Iso-16-cyclohexyl-tetranor prostaglandin E2
0 ImagesCat. No.: HY-118681CAS No.: 53319-30-58-Iso-16-cyclohexyl-tetranor prostaglandin E2 is an analog of Prostaglandin E2 (HY-101952).
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Etersalate
0 ImagesCat. No.: HY-101606CAS No.: 62992-61-4Synonyms: Eterylate; EtherylateEtersalate inhibits platelet function and decreases thromboxane A2 (TXA2) levels.
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Terbogrel
0 ImagesCat. No.: HY-19189CAS No.: 149979-74-8Synonyms: BIBV 308SETerbogrel is an orally available thromboxane A2 receptor antagonist and a thromboxane A2 synthase inhibitor, with both IC50s of about 10 nM.
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Aligeron
0 ImagesCat. No.: HY-101602CAS No.: 70713-45-0Aligeron is a non-selective prostaglandin (PG) antagonist, and has vasodilatory properties.
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AZ-1355
0 ImagesAZ-1355 is an orally active and effctive lipid-lowering agent. AZ-1355 inhibits platelet aggregation in vivo and elevates the prostaglandin I2/thromboxane A2 ratio in vitro.
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MTPPA
0 ImagesSynonyms: (Rac)-M-5011MTPPA ((Rac)-M-5011) is an orally active anti-inflammatory, analgesic and anti-rheumatic compound. MTPPA mediates the inhibition of prostaglandin biosynthesis. MTPPA acts as a four-point tetrahedral organophosphonate bridging ligand. MTPPA can be used in research related to inflammation, pain and adjuvant arthritis.
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16-Phenoxy tetranor prostaglandin F2α
0 ImagesCat. No.: HY-139063CAS No.: 51705-19-2Synonyms: 16-Phenoxy tetranor PGF2α16-phenoxy tetranor Prostaglandin F2α (16-phenoxy tetranor PGF2α) is a metabolically stable analog of PGF2α. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α.
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BM567
0 ImagesCat. No.: HY-124150CAS No.: 284464-77-3BM567 is a sulfonylurea compound (compound 1), which exhibits antithrombogenic efficacy as thromboxane A2 receptor (TXR) antagonists and thromboxane A2 synthase (TXS) inhibitors, with IC50s of 1.1 and 12 nM, respectively.
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FR-181877
0 ImagesCat. No.: HY-116613CAS No.: 172936-99-1FR-181877 (compound 4) is a non-prostaglandin PGI2 agonist. FR-181877 inhibits ADP (HY-W010918)-induced human platelet aggregation with an IC50 value of 0.081 μM.
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13(R),14(R)-epoxy Fluprostenol isopropyl ester
0 ImagesCat. No.: HY-158550CAS No.: 2557329-36-7Synonyms: 13(R),14(R)-epoxy Travoprost13(R),14(R)-epoxy Fluprostenol isopropyl ester is a Prostaglandin derivative.
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(Z)-Isbogrel
0 ImagesCat. No.: HY-119890ACAS No.: 89667-39-0Synonyms: (Z)-CV-4151(Z)-Isbogrel ((Z)-CV-4151) is a potent thromboxane A2 (TxA2) synthase inhibitor with an IC50 of 0.9 nM. (Z)-Isbogrel inhibits serum TxB2 production, with an ED50 of 0.01 mg/kg upon intravenous administration and an ED50 of 0.05 mg/kg upon oral administration in rats, and it exhibits no PAF receptor antagonistic activity. (Z)-Isbogrel can be used in research related to cardiovascular and cerebrovascular diseases.
