Prostaglandin Receptor
Prostaglandin receptor, a sub-family of cell surface seven-transmembrane receptors, are the G-protein-coupled receptors. There are currently ten known prostaglandin receptors on various cell types. Prostaglandins bind to a subfamily of cell surface seven-transmembrane receptors, G-protein-coupled receptors. These receptors are named: DP1-2-DP1, DP2 receptors, EP1-4-EP1, EP2, EP3, EP4 receptors, FP-FP, IP1-2-IP1, IP2 receptors, TP-TP receptor. The prostaglandins are a group of hormone-like lipid compounds that are derived enzymatically from fatty acids and have important functions in the animalbody. There are currently ten known prostaglandin receptors on various cell types.
Prostaglandin Receptor Isoform Specific Products
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Prostaglandin Receptor Inhibitors
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Prostaglandin Receptor Agonists
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Prostaglandin Receptor Antagonists
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Prostaglandin Receptor Activators
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Prostaglandin Receptor Modulators
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Prostaglandin Receptor Inducers
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Prostaglandin Receptor Degrader
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Prostaglandin Receptor Controls
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Prostaglandin Receptor Ligands
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Prostaglandin Receptor Related Products (767)
Related Products (767)
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Antibodies (2)
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Prostaglandin Receptor Isoform Comparison
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16-Phenyl tetranor Prostaglandin F2α
0 ImagesCat. No.: HY-137544CAS No.: 38315-48-9Synonyms: 16-Phenyl tetranor PGF2α16-phenyl tetranor Prostaglandin F2α (16-phenyl tetranor PGF2α) is a metabolically stable analog of PGF2α. The affinity of 16-phenyl tetranor PGF2α at the FP receptor of ovine luteal cells is poor (8.7%) compared to PGF2α.
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Samixogrel
0 ImagesCat. No.: HY-123400CAS No.: 133276-80-9Synonyms: DTTX30; DT-TX 30 SESamixogrel is an inhibitor of thromboxane A2 receptor and thromboxane synthesis.
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Bimatoprost-d5
0 ImagesCat. No.: HY-B0191SPurity: 98.24%Synonyms: AGN 192024 d5Bimatoprost-d5 is a deuterium labeled Bimatoprost. Bimatoprost is a prostaglandin analog and is a topical hypotensive agent frequently used for treating ocular hypertension and glaucoma. Bimatoprost also has an antiadipogenic effect.
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CRTh2 antagonist 3
0 ImagesCat. No.: HY-135773CAS No.: 312928-72-6CRTh2 antagonist 3 is a potent chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTh2) antagonist. CRTh2 antagonist 3 enhances the activity of PDK1 toward a short peptide substrate, with an EC50 of 2 μM and a Kd of 8.4 μM. CRTh2 antagonist 3 has the potential for cardiovascular inflammation.
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Triflusal-d3
0 ImagesCat. No.: HY-B0531SCAS No.: 2748541-63-9Triflusal-d3 is deuterium labeled Triflusal (HY-B0531). Triflusal is an orally bioavailable, blood-brain barrier-permeable dual Cyclooxygenase-1 (COX-1)/cAMP phosphodiesterase inhibitor. Triflusal inhibits platelet aggregation, NF-κB activation, iNOS activity, and prostaglandin synthesis in ischaemic tissue. Triflusal stimulates neutrophil nitric oxide production, eNOS protein expression, and cNOS activity. Triflusal alleviates cerebral ischemic injury in rats and ameliorates pathological lesions and related gene expression in transgenic Alzheimer’s disease models. Triflusal can be used for the research of thromboembolic/ischemic cardiovascular and cerebrovascular diseases, and Alzheimer’s disease.
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Meteneprost potassium
0 ImagesCat. No.: HY-106077ACAS No.: 122576-55-0Synonyms: U 46785 potassiumMeteneprost (U 46785) potassium is a cervical dilator that stimulates uterine contractions and dilates the cervical canal.
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EP2 receptor agonist 2
0 ImagesCat. No.: HY-128496CAS No.: 1807780-00-2EP2 receptor agonist 2 (compound 18a) is a potent and selective G protein-biased EP2 receptor agonist (hEP2G protein EC50 = 13 nM, hEP2β arrestin EC50 > 10000 nM). EP2 receptor agonist 2 exhibits excellent selectivity over hEP1/3/4, hIP and hFP (EC50s > 10000 nM).
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IP receptor agonist 1
0 ImagesCat. No.: HY-175986CAS No.: 3029113-61-6IP receptor agonist 1 (compound 6c-14S) is an orally active I prostanoid receptor agonist, with an IC50 of 0.15 μM for inhibiting platelet aggregation induced by ADP (HY-W010918,300 μM) in rabbit platelet-rich plasma. IP receptor agonist 1 can be used for study of Pulmonary arterial hypertension.
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Prostaglandin F2α ethyl amide
0 ImagesCat. No.: HY-118599CAS No.: 54130-36-8Prostaglandin F2α ethyl amide is an analog of Prostaglandin F2α (HY-12956). Prostaglandin F2α ethyl amide is supposed to be potent lowering intraocular pressure (IOP) for its N-ethyl amide group, like Bimatoprost (HY-B0191).
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8-iso-15-keto Prostaglandin F2α
0 ImagesCat. No.: HY-125626CAS No.: 191919-01-4Synonyms: 8-iso-15-keto PGF2α8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a partial agonist for Thromboxane receptor (TP), which exhibits a vasoconstrictor efficacy with a pD2 of 5.8. 8-iso-15-keto Prostaglandin F2α mediates a weak relaxation of rats aorta rings at high concentration.
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Nileprost
0 ImagesCat. No.: HY-106790CAS No.: 71097-83-1Nileprost is a prostacyclin analogue. Nileprost is a mixed type PGI2/PGE2 agonist. Nileprost can be studied in research on acute myocardial ischemia.
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Diftalone
0 ImagesCat. No.: HY-107340CAS No.: 21626-89-1Synonyms: Aladione; L 5418Diftalone (Aladione) is an anti-inflammatory agent. Diftalone can be used for research of inflammatory disease, such as rheumatoid arthritis.
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11-Deoxy-16,16-dimethyl-PGE2
0 ImagesCat. No.: HY-136696CAS No.: 53658-98-311-Deoxy-16,16-dimethyl-PGE2, a Prostaglandin E2 analog, is a EP2 and EP3 receptors agonist. 11-Deoxy-16,16-dimethyl-PGE2 protects proximal renal tubular epithelial cells from potent nephrotoxicity-induced cell damage by exerting anti-oxidative stress.
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Prostaglandin F2α dimethyl amide
0 ImagesCat. No.: HY-139119CAS No.: 68192-15-4Prostaglandin F2α dimethyl amide is an antagonist for Prostaglandin F2α (HY-12956), which blocks 50% contraction on gerbilMeriones unguiculatus colon induced by PGF2α at 3.2 μg/mL.
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ONO-8130
0 ImagesCat. No.: HY-110198CAS No.: 459841-96-4
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GW 848687X
0 ImagesCat. No.: HY-14466CAS No.: 612831-24-0GW 848687X is a selective, orally active prostaglandin EP1 receptor antagonist for the inhibition of inflammatory pain. The oral bioavailability of GW 848687X was 54% in rats and 53% in dogs. GW 848687X has a half-life of 2 hours and has inhibitory potential for both acute and chronic pain.
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11-Deoxy-11-methylene PGD2
0 ImagesCat. No.: HY-112533CAS No.: 100648-29-1Synonyms: 11d-11m-PGD2; 11-Deoxy-11-Methylene prostaglandin D211-Deoxy-11-methylene PGD2 (11d-11m-PGD2) is a chemically stable, isosteric analogue of Prostaglandin 2 in which the 11-keto group is replaced by an exocyclic methylene. 11-Deoxy-11-methylene PGD2 is significantly stimulating the storage of fats suppressed in the presence of Indomethacin.
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15(R)-15-Methyl prostaglandin F2α methyl ester
0 ImagesCat. No.: HY-158937CAS No.: 35700-22-2Synonyms: 15(R)-Methyl carboprost; 15(R)-15-Methyl PGF2α methyl ester15(R)-15-Methyl prostaglandin F2α methyl ester (15(R)-Methyl carboprost) (compound 15R) is a 15-methyl substituted prostaglandin analog, a member of the prostaglandin family, with potential biological activities in a variety of biological systems, but its specific activity mechanism and application details are not described in detail from the existing information.
