Free Radical Scavengers
Free radical scavengers are bioactive substances that eliminate reactive free radicals. Free radicals with unpaired electrons easily damage lipids, proteins and DNA, causing oxidative stress and cell aging.
Free radical scavengers neutralize radicals by donating electrons or hydrogen atoms to form stable inert compounds. Their scavenging capacity is measured by in vitro assays including DPPH and ABTS tests.
Common natural scavengers are polyphenols, flavonoids, vitamin C and vitamin E. They are widely studied for food preservation, cosmetic anti-oxidation and treatments for oxidative damage-related diseases.
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Free Radical Scavengers Produits associés (379)
Produits associés (379)
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Gaultherin
0 ImagesGaultherin is an orally active non-steroidal anti-inflammatory agent. Gaultherin selectively inhibits NF-κB, MAPK, COX-2 (IC50 = 0.35 mg/mL), LOX (IC50 = 0.56 mg/mL) and HYAL (IC50 = 28.58 μg/mL) to exert anti-inflammatory, antipyretic and analgesic effects. Gaultherin exhibits modest direct antioxidant capacity, greater in cell-based models. Gaultherin does not affect COX-1 so that avoids the common gastrointestinal side effects of Aspirin (HY-14654).
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Kaempferol 3,7,4'-trimethyl ether
0 ImagesKaempferol 3,7,4'-trimethyl ether is an O-methylated kaempferol flavonol aglycone distributed in Siparuna gigantotepala, Aframomum arundinaceum and Siparuna guianensis. Kaempferol 3,7,4'-trimethyl ether exhibits antioxidant activity. Kaempferol 3,7,4'-trimethyl ether suppresses the proliferation of leukemia cells and exerts selective cytotoxicity against both drug‑sensitive and multi‑factorial drug‑resistant cancer cells. Kaempferol 3,7,4'-trimethyl ether can be applied in the research of multidrug‑resistant cancers.
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Matairesinoside
0 ImagesMatairesinoside is a lignan with antibacterial and antioxidant activities. Matairesinoside also shows virus-cell fusion inhibitory activity.
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Erigeside I
0 ImagesErigeside I is a free radical scavenger isolated from Erigeron breviscapus.
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Lyoniresinol
0 ImagesLyoniresinol is a lignan isolated from the Tarenna attenuata with antioxidant activities. Lyoniresinol has radical scavenging activities against DPPH with an IC50 of 82.4 μM.
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MAO-B-IN-64
0 ImagesCat. No.: HY-189245MAO-B-IN-64 is an orally active, blood-brain barrier-permeable reversible competitive inhibitor of monoamine oxidase B, with an IC50 of 0.35 nM against human MAO-B and a Ki of 0.22 nM for human MAO-B. MAO-B-IN-64 exhibits antioxidant effects by scavenging free radicals. MAO-B-IN-64 exerts anti-neuroinflammatory effects by inhibiting the release of pro-inflammatory factors. MAO-B-IN-64 acts as an H2S donor by releasing hydrogen sulfide. MAO-B-IN-64 can be applied in the research of Parkinson's disease.
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Edaravone solution
0 ImagesCat. No.: HY-FLB0099CAS No.: 89-25-8Synonyms: MCI-186 solutionEdaravone solution is mainly composed of Edaravone (HY-B0099). Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Edaravone can improve the neurological symptoms, daily living activities and functional impairments caused by acute cerebral infarction.
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Pyruvic acid-13C2-1 sodium
0 ImagesSynonyms: Sodium 2-oxopropanoate-13C2; Acetylformic acid-13C2-1 sodium2-Oxopropanoate-13C2 (sodium) is the 13C labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS.
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Homovanillyl alcohol (Standard)
0 ImagesHomovanillyl alcohol (Standard) is the analytical standard of Homovanillyl alcohol (HY-N7513). This product is intended for research and analytical applications. Homovanillyl alcohol is a biological metabolite of Hydroxytyrosol, and belongs to the class of phenolic organic compounds. Homovanillyl alcohol alleviates cellular oxidative stress and inflammatory responses by scavenging free radicals, inhibiting the phosphorylation of the p38 and JNK MAP kinase pathways, as well as suppressing NF-κB-driven transcription and nuclear translocation. It can be used in studies related to cardiovascular diseases and allergic asthma.
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Orthosporin
0 ImagesCat. No.: HY-W751002CAS No.: 118063-79-9Synonyms: (+)-OrthosporinOrthosporin ((+)-Orthosporin), a phytotoxic isocoumarin compound, is a microbial secondary metabolite. Orthosporin can be isolated from the endophytic fungus Lasiodiplodia tbeobromae. Orthosporin has potent antibacterial activity against B. subtilis, E. coli and P. aeruginosa. Orthosporin also has antioxidant activity against DPPH radical and antiviral activities with inhibition of HIV-1 reverse transcriptase activity.
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Xanthone V1a
0 ImagesCat. No.: HY-N10985CAS No.: 103450-96-0Xanthone V1a, a derivative of Xanthone (HY-N0126), is an antioxidant that can be found in the roots of Cudrania tricuspidata and twig extracts of Maclura fruticosa. Xanthone V1a exerts cytotoxic effects against colon, hepatocellular, and gastric carcinoma cells. Xanthone V1a exhibits scavenging activitys against DPPH and ABTS. Xanthone V1a can be used for the research of colon carcinoma, hepatocellular carcinoma, and gastric carcinoma.
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Demethyltorosaflavone C
0 ImagesCat. No.: HY-N21616CAS No.: 145194-15-6Demethyltorosaflavone C is a Free Radical Scavenger, with DPPH• scavenging IC50 values of 47.7 μM and 1.36 mM in different experimental systems. The catechol group on the B ring of Demethyltorosaflavone C promotes hydrogen donation and resonance stabilization of the phenoxyl radical, thereby exerting its free radical scavenging effect. Demethyltorosaflavone C can be used in studies on oxidative stress and natural product flavonoids.
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Sigma-1 receptor modulator-1
0 ImagesSigma-1 receptor modulator-1 is a sigma-1 receptor modulator and acetylcholinesterase (AChE) inhibitor. Sigma-1 receptor modulator-1 binds to sigma-1 receptors in guinea pigs with a Ki of 1.8 nM. Sigma-1 receptor modulator-1 modulates chaperone proteins, restores calcium homeostasis, and controls ROS production. Sigma-1 receptor modulator-1 inhibits AChE activity and scavenges free radicals. Sigma-1 receptor modulator-1 can be used for research on neurodegenerative diseases.
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Tyrosinase-IN-49
0 ImagesCat. No.: HY-181029Tyrosinase-IN-49 (Compound 12) is a potent and mixed-type chalcone-based tyrosinase inhibitor with an IC50 of 0.19 μM. Tyrosinase-IN-49 has potent antioxidant potential with significant DPPH and ABTS radical scavenging capacity. Tyrosinase-IN-49 can chelate the binuclear copper ions in the active center of tyrosinase and reduce Cu2+ to Cu+, thereby reducing the catalytic activity of the enzyme. Tyrosinase-IN-49 has low cytotoxicity for HEK293 cells and zebrafish embryo. Tyrosinase-IN-49 shows antibrowning effects to improve food quality and can be used for research of food preservation.
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Loddigesiinol A
0 ImagesCat. No.: HY-N17891CAS No.: 1252577-62-0Loddigesiinol A is a phenanthrene compound found in Dendrobium loddigesii. Loddigesiinol A acts as a DPPH radical scavenger with an IC50 of 26.1 μM. Loddigesiinol A also inhibits nitric oxide production. Loddigesiinol A is applicable to inflammation-related research.
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4,5-O-Dicaffeoylquinic acid ethyl ester
0 ImagesCat. No.: HY-N17733CAS No.: 1632482-02-04,5-O-Dicaffeoylquinic acid ethyl ester is an ABTS free radical scavenger with an IC50 of 5.95 μM. 4,5-O-Dicaffeoylquinic acid ethyl ester shows no antibacterial activity against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. 4,5-O-Dicaffeoylquinic acid ethyl ester can be used in liver injury protection studies.
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(E/Z)-erythro-Guaiacylglycerol β-coniferyl ether
0 ImagesCat. No.: HY-N3864ACAS No.: 117703-33-0(E/Z)-erythro-Guaiacylglycerol β-coniferyl ether is a lignan compound found in Canadian maple syrup. (E/Z)-erythro-Guaiacylglycerol β-coniferyl ether exerts antioxidant acyivity and can scavenge DPPH radica. (E/Z)-erythro-Guaiacylglycerol β-coniferyl ether can be used for the research of inflammation.
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6-Prenylquercetin-3-Me ether
0 ImagesCat. No.: HY-N9051CAS No.: 151649-34-26-Prenylquercetin-3-Me ether is a natural product that can be extracted from G. uralensis leaves. 6-Prenylquercetin-3-Me ether has radical scavenging activity toward DPPH. 6-Prenylquercetin-3-Me ether also has inhibitory activity against α-glucosidase.
