Free Radical Scavengers
Free radical scavengers are bioactive substances that eliminate reactive free radicals. Free radicals with unpaired electrons easily damage lipids, proteins and DNA, causing oxidative stress and cell aging.
Free radical scavengers neutralize radicals by donating electrons or hydrogen atoms to form stable inert compounds. Their scavenging capacity is measured by in vitro assays including DPPH and ABTS tests.
Common natural scavengers are polyphenols, flavonoids, vitamin C and vitamin E. They are widely studied for food preservation, cosmetic anti-oxidation and treatments for oxidative damage-related diseases.
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Free Radical Scavengers Related Products (379)
Related Products (379)
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(-)-Epiafzelechin
0 Images(−)-Epiafzelechin is a COX-1 inhibitor with an IC50 of approximately 15 μM against COX-1 activity. (−)-Epiafzelechin also exhibits DPPH free radical scavenging activity, with an EC50 of 20.9 μM. (−)-Epiafzelechin promotes osteoblast differentiation by increasing ALP activity, ECM collagen content and Runx2 expression, while reducing the growth of osteoclast precursors and RANKL-induced TRAP activity, thereby regulating the bone remodeling process. (−)-Epiafzelechin alleviates ovariectomy-induced bone loss. (−)-Epiafzelechin can be used in studies related to bone remodeling, postmenopausal osteoporosis, inflammatory responses and oxidative stress.
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4-Methoxyphenyl isothiocyanate
0 ImagesSynonyms: 4-Methylphenyl ITC4-Methoxyphenyl isothiocyanate (4-Methylphenyl ITC) is an antioxidant, with a IC50 value of 1.25 mM for scavenging DPPH radicals. ORAC testing indicates its antioxidant capacity as 11.7 mM TE (indicating that the antioxidant efficacy of this compound is equivalent to 11.7 mmol of Trolox (HY-101445, a standard antioxidant) under the same conditions), and it extends the oxidation process by approximately 9180 seconds in the Briggs–Rauscher reaction. Additionally, 4-Methoxyphenyl isothiocyanate exhibits moderate cholinesterase inhibitory activity, with an inhibition rate of 30.4% against acetylcholinesterase (AChE) and 17.9% against butyrylcholinesterase (BChE). 4-Methoxyphenyl isothiocyanate holds potential for research in the fields of antioxidation and neurological disorders.
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Tripropylammonium hexafluorophosphate
0 ImagesTripropylammonium hexafluorophosphate is a potent, cell-permeable free radical scavenger suitable for the detection of superoxide radicals and peroxynitrite in vitro.
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(±)-Taxifolin-13C3
0 ImagesCat. No.: HY-N0136S1Purity: 99.63%Synonyms: (±)-Dihydroquercetin-13C3(±)-Taxifolin-13C3 ((±)-Dihydroquercetin-13C3) is a derivative of (±)-Taxifolin, labeled with 13C3. (±)-Taxifolin is the racemate of Taxifolin. Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity.
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(±)-Taxifolin
0 ImagesSynonyms: (±)-Dihydroquercetin(±)-Taxifolin ((±)-Dihydroquercetin) is the racemate of Taxifolin (HY-N0136). Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity.
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Maritimetin
0 ImagesMaritimein is an aurone that can be isolated from Coreopsis tinctoria. Maritimein shows strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity with an IC50 value of 4.12 μM. Maritimein can be used for the research of cardiovascular disease.
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Methyl isovanillate
0 ImagesMethyl isovanillate is a secondary metabolite isolated from Vitex agnus-castus. Methyl isovanillate does not exhibit significant activity in the DPPH free radical scavenging experiment.
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Butyl caffeate
0 ImagesSynonyms: Caffeic acid butyl esterButyl caffeate (Caffeic acid butyl ester) is a caffeic acid derivative with antioxidant activity and lipophilicity (DPPH IC50 = 14.1 μM). Butyl caffeate protects neuronal PC12 cells against oxidative stress. Butyl caffeate can be used for oxidative stress related and neurodegenerative diseases research.
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2-Hydroxydocosanoic acid
0 Images2-Hydroxydocosanoic acid has antioxidant, cholinesterase inhibitory, and antimicrobial activities.
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Kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside
0 ImagesKaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside is an antioxidant with an IC50 of 26.6 μM (DPPH assay).
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Nelonemdaz potassium
0 ImagesSynonyms: Salfaprodil; Neu2000 potassiumNelonemdaz (Salfaprodil) potassium is an NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). Nelonemdaz potassium is also a free radical scavenger. Nelonemdaz potassium has excellent neuroprotection against NMDA- and free radical-induced cell death.
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Isoamyl benzoate
0 ImagesSynonyms: Isopentyl benzoateIsoamyl benzoate (Isopentyl benzoate) is a natural aromatic ester compound. Isoamyl benzoate exhibits free radical scavenging capabilities against DPPH and ABTS, with its IC50 values being 9.55 μg/mL and 7455.54 μM TE/g respectively. Isoamyl benzoate can be used in antioxidant research.
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Antioxidant agent-7
0 ImagesAntioxidant agent-7 (SD-7) is a benzodiazepine derivative with antioxidant activity with an IC50 value of 470 nM to scavenge DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical.
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3,5-Dicaffeoyl-epi-quinic acid
0 ImagesCat. No.: HY-N9895CAS No.: 879305-14-33,5-Dicaffeoyl-epi-quinic acid can be extracted from Chrysanthemum morifolium. 3,5-Dicaffeoyl-epi-quinic acid has antioxidant activities. 3,5-Dicaffeoyl-epi-quinic acid can scavenge DPPH radical and superoxide anion radical, with IC50s of 5.6 and 2.9 μg/mL respectively.
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Tyrosinase-IN-18
0 ImagesCat. No.: HY-157123Purity: 99.33%Tyrosinase-IN-18 (compound 6) is a potent tyrosinase inhibitor. Tyrosinase-IN-18 inhibits melanogenesis in B16F10 mammalian cells. Tyrosinase-IN-18 has strong antioxidant activities against ROS, ABTS+, and DPPH radicals.
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Edaravone-d5
0 ImagesSynonyms: MCI-186-d5Edaravone-d5 is a deuterium labeled Edaravone. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator.
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Tetrahydrothiophen-3-one
0 ImagesTetrahydrothiophen-3-one is an endogenous metabolite. Tetrahydrothiophen-3-one scavenges DPPH free radicals. Tetrahydrothiophen-3-one can be used in studies related to Candida infections.
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Gliquidone-d6
0 ImagesCat. No.: HY-B1114SPurity: 99.87%Synonyms: AR-DF 26-d6Gliquidone-d6 (AR-DF 26-d6) is the deuterated-labeled Gliquidone (HY-B1114). Gliquidone can bind to the pancreatic β-cells and increases insulin release to regulate blood glucose levels. Gliquidone significantly decreases LPS (HY-D1056)-induced proinflammatory responses and inhibits ERK/STAT3/NF-κB phosphorylation in BV2 microglial cells. Gliquidone can suppress microgliosis, microglial hypertrophy mediated by LPS, and proinflammatory cytokine COX-2 and IL-6 levels in murine model. Gliquidone also exhibits good anticancer activity in lung carcinoma cells. Gliquidone has antioxidant property. Gliquidone can be studied in research for type 2 diabetes and cancers.
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Norbergenin
0 ImagesNorbergenin is a polyphenolic isocoumarin derivative. Norbergenin acts as a non-competitive inhibitor of bovine adrenal tyrosine hydroxylase (TH) with a Ki value of 69.6 μM. Norbergenin inhibits lipopolysaccharide-induced inflammatory responses in macrophages by suppressing the activation of NF-κB, MAPK and STAT3, as well as blocking metabolic reprogramming. Norbergenin inhibits aluminum chloride-induced oxidative stress and apoptosis and restores neurocognitive parameters. Norbergenin scavenges ROS through multiple mechanisms and protects cell membranes from lipid peroxidation damage. Norbergenin can be used in research related to Alzheimer's disease, peptic ulcer and arthritis.
