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Anti-virus agent 1 

Cat. No.: HY-131233
Handling Instructions

Anti-virus agent 1 (compound 4i), a phosphoramidate prodrug of GS-5734 (HY-104077; Remdesivir), has potent antiviral activity. Anti-virus agent 1 is used for the research of coronavirus and Ebola virus (EBOV).

For research use only. We do not sell to patients.

Anti-virus agent 1 Chemical Structure

Anti-virus agent 1 Chemical Structure

CAS No. : 1911578-83-0

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Description

Anti-virus agent 1 (compound 4i), a phosphoramidate prodrug of GS-5734 (HY-104077; Remdesivir), has potent antiviral activity. Anti-virus agent 1 is used for the research of coronavirus and Ebola virus (EBOV)[1][2].

In Vitro

Anti-virus agent 1 (compound 4i) has antiviral activity for EBOV in HeLa cell (EC50=1845 nM), HMVEC cell (TERT-immortalized human foreskin microvascular endothelial cells; ATCC-4025; EC50=367 nM), human macrophages (EC50=297 nM). Anti-virus agent 1 has a CC50 of 21 μM in MT4 cell (human leukemia T-cell)[1].

Molecular Weight

560.50

Formula

C₂₄H₂₉N₆O₈P

CAS No.

1911578-83-0

SMILES

N#C[[email protected]@]([[email protected]@H]([[email protected]@H]1O)O)(C2=CC=C3N2N=CN=C3N)O[[email protected]@H]1CO[[email protected]](OC4=CC=CC=C4)(N[[email protected]@H](C)C(OC(C)C)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Anti-virus agent 1OthersGS-5734antiviralcoronavirusEbolavirusEBOVRemdesivirInhibitorinhibitorinhibit

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