AB-3PRGD2
AB-3PRGD2 is a radiotherapeutic agent targeting integrin αvβ3. AB-3PRGD2 shows improved tumor uptake and prolonged tumor retention, leading to significantly enhanced tumor growth suppression. AB-3PRGD2 can remodel the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.
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- CAS. Nr.: 2416165-76-7
- Formel: C137H215IN30O45S
- Molecular Weight:3161.32
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Chemical Information
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CAS. Nr. 2416165-76-7
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Molecular Weight 3161.32
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Formel C137H215IN30O45S
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SMILES
OC(CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(N[C@@H](CSC2C(N(CCCCCC(NCCOCCOCCOCCOCCC(N[C@@H](CCC(NCCOCCOCCOCCOCCC(NCCCC[C@@H]3NC([C@@H](CC4=CC=CC=C4)NC([C@H](CC(O)=O)NC(CNC([C@H](CCCNC(N)=N)NC3=O)=O)=O)=O)=O)=O)=O)C(NCCOCCOCCOCCOCCC(NCCCC[C@@H]5NC([C@@H](CC6=CC=CC=C6)NC([C@H](CC(O)=O)NC(CNC([C@H](CCCNC(N)=N)NC5=O)=O)=O)=O)=O)=O)=O)=O)=O)C(C2)=O)=O)C(N[C@H](CCCCNC(CCCC7=CC=C(I)C=C7)=O)C(O)=O)=O)=O)CC1)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
AB-3PRGD2 Related Classifications
HY-171331 Related Classifications
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