BAY-155
BAY-155 is a potent and selective menin-MLL tool inhibitor, with an IC50 of 8 nM. BAY-155 leads to a strong expression down-regulation of the MEIS1 gene and up-regulation of CD11b and MNDA genes. BAY-155 shows anti-proliferative effects in AML/ALL (acute myeloid/lymphoblastic leukemia) models.
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- CAS. Nr.: 2163769-52-4
- Formel: C28H28F3N7OS
- Molecular Weight:567.63
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Chemical Information
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CAS. Nr. 2163769-52-4
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Molecular Weight 567.63
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Formel C28H28F3N7OS
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SMILES
O=C(N)CN1C(C#N)=CC2=C1C=CC(CN(CC3)CCC43CN(C5=C(C=C(CC(F)(F)F)S6)C6=NC=N5)C4)=C2C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
BAY-155 Related Classifications
HY-160018 Related Classifications
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