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Art. -Nr.: HY-184911

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CDK6 ligand-3

CDK6 ligand-3 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs) that targets CDK6. CDK6 ligand-3 can be used to synthesize the PROTAC JHK-02-108-2 (HY-184910).

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Formel: C₂₆H₂₆F₄N₆O₃
Molecular Weight:546.52

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

CDK6 ligand-3 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target^[1]

CDK6

Alle CDK Isoform-spezifische Produkte anzeigen :

In Vitro

CDK6 ligand-3 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs) that targets CDK6. CDK6 ligand-3 can be used to synthesize the PROTAC JHK-02-108-2 (HY-184910)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 546.52
Formel C₂₆H₂₆F₄N₆O₃
SMILES

FC(F)(F)C(C=C(NC(NC1=C(F)C=C(OC2=CC(C(NC)=O)=NC=C2)C=C1)=O)C=C3)=C3CN4CCNCC4
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Kim JH, et al. A Type II CDK6 Degrader Enables Cellular Targeting beyond the Limits of Type II Inhibition. Journal of the American Chemical Society. 2026 Jul 08;148(26):27951-27964. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
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CDK6 ligand-3

Alle CDK Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

CDK6 ligand-3 Related Classifications

HY-184911 Related Classifications