Lupalbigenin
Based on 1 Customer Validation
Lupalbigenin is an isoflavonoid compound that can be isolated and extracted from Licorice and Derris scandens. Lupalbigenin exhibits anti-inflammatory, anti-tumor, anti-oxidative stress, anti-metastatic, and anti-dermatophyte effects. Lupalbigenin significantly downregulates key survival factors such as pAKT/AKT, pERK/ERK, and the anti-apoptotic protein BCL-2 in cancer cells, thereby promoting apoptosis. Lupalbigenin is also an insect antifeedant and is toxic to chewing and piercing-sucking insects. Lupalbigenin can be used in cancer and fungal infection research.
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- Reinheit : 98%
- CAS. Nr.: 76754-24-0
- Formel: C25H26O5
- Molecular Weight:406.47
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Speicherung:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
Bcl-2 |
ERK |
Akt |
In Vitro
Lupalbigenin promotes detachment-induced cell death and downregulates pAKT/AKT, pERK/ERK, and BCL-2 proteins in human lung cancer cells[1].
Lupalbigenin has antifungal activity in dermatophytes[1].
Lupalbigenin has antifeedant and toxic effects in chewing and sucking insects[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 76754-24-0
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Appearance Solid
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Molecular Weight 406.47
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Formel C25H26O5
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Color White to off-white
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SMILES
O=C1C2=C(O)C(C/C=C(C)/C)=C(O)C=C2OC=C1C3=CC(C/C=C(C)/C)=C(O)C=C3
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Structure Classification
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Reinheit & Dokumentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
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