CD40
CD40 (TNFRSF5) is a co-stimulatory receptor of the TNF receptor superfamily and the central orchestrator of humoral and cellular immunity. CD40 is a 45-50 kDa type I transmembrane protein with four extracellular cysteine-rich domains, expressed on B cells, dendritic cells, macrophages, monocytes, epithelial and endothelial cells, fibroblasts and various carcinomas. Its ligand CD40L (CD154), transiently expressed on activated CD4+ T cells and platelets, triggers receptor trimerization and recruitment of TRAF2/3/5/6, activating canonical and non-canonical NF-κB, MAPK, JAK3-STAT3 and PI3K pathways. In B cells, CD40 signaling drives germinal center formation, immunoglobulin class switching, somatic hypermutation, memory B-cell and plasma-cell differentiation; in dendritic cells, it licenses antigen presentation and interleukin-12 production. CD40-CD40L defects cause X-linked hyper-IgM immunodeficiency, whereas sustained CD40 signaling contributes to atherosclerosis, autoimmune inflammation and B-cell lymphomas; agonistic CD40 antibodies and CD40L blockers are both therapeutic development tracks in cancer and autoimmunity.
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CD40 Recombinant Proteins (18)
CD40 Protein, Human (HEK293, His)
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Art. -Nr.: HY-P73499A
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily Member 5; CD40 Molecule; Tumor Necrosis Factor Receptor Superfamily, Member 5
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CD40 Protein, Human (Biotinylated, HEK293, His-Avi)
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Art. -Nr.: HY-P78091
Reinheit: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
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CD40 Protein, Mouse (HEK293, Fc)
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Art. -Nr.: HY-P72911
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
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CD40 Protein, Human (HEK293, Fc)
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Art. -Nr.: HY-P72910
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
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CD40 Protein, Mouse (HEK293, His)
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Art. -Nr.: HY-P72724
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
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CD40 Protein, Cynomolgus (HEK293, His)
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Art. -Nr.: HY-P72725
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
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CD40 Protein, Cynomolgus (HEK293, Fc)
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Art. -Nr.: HY-P7837
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
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CD40 Protein, Rat (HEK293, His)
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Art. -Nr.: HY-P74295
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
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CD40 Protein, Rhesus Macaque (HEK293, His)
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Art. -Nr.: HY-P75408
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
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CD40 Protein, Canine (HEK293, His)
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Art. -Nr.: HY-P75411
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
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CD40 Protein, Human (Biotinylated, HEK293, Fc-Avi)
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Art. -Nr.: HY-P72909
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
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CD40 Protein, Rabbit (HEK293, His)
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Art. -Nr.: HY-P78612
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
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CD40 Protein, Mouse (Biotinylated , HEK293, His-Avi)
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Art. -Nr.: HY-P74298
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
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CD40 Protein, Rat (HEK293, Fc)
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Art. -Nr.: HY-P74296
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
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CD40 Protein, Rhesus Macaque (HEK293, Fc)
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Art. -Nr.: HY-P75409
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
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CD40 Protein, Canine (HEK293, Fc)
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Art. -Nr.: HY-P75412
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
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CD40 Protein, Canine (HEK293)
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Art. -Nr.: HY-P75413
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
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CD40 Protein, Mouse (Biotinylated , HEK293, Fc-Avi)
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Art. -Nr.: HY-P704999
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily Member 5; CD40 Molecule; Tumor Necrosis Factor Receptor Superfamily, Member 5
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
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Capetin (28-54), human
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Synonyms: Serpin B6; Cytoplasmic Antiproteinase; cap; Peptidase Inhibitor
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
