BRD4 Inhibitor-29
BRD4 Inhibitor-29 (SQ-17) is a BRD4 inhibitor, with an IC50 of <100 nM. BRD4 Inhibitor-29 shows antiproliferative effect against prostate cancer cells.
For research use only. We do not sell to patients.
- CAS No.: 902563-50-2
- Formula: C21H28N2O3
- Molecular Weight:356.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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BRD4 <100 nM nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CWR22R | IC50 |
17.48 μM
Compound: SQ-17
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Cytotoxicity against human androgen-independent/androgen-responsive 22Rv1 cells assessed as cell viability incubated for 96 hrs by MTT assay
Cytotoxicity against human androgen-independent/androgen-responsive 22Rv1 cells assessed as cell viability incubated for 96 hrs by MTT assay
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[PMID: 38153295] |
| DU-145 | IC50 |
87.12 μM
Compound: SQ-17
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Cytotoxicity against human DU-145 cells assessed as cell viability incubated for 96 hrs by MTT assay
Cytotoxicity against human DU-145 cells assessed as cell viability incubated for 96 hrs by MTT assay
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[PMID: 38153295] |
| LNCaP | IC50 |
4.03 μM
Compound: SQ-17
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Cytotoxicity against human AR-dependent LNCaP cells assessed as cell viability incubated for 96 hrs by MTT assay
Cytotoxicity against human AR-dependent LNCaP cells assessed as cell viability incubated for 96 hrs by MTT assay
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[PMID: 38153295] |
| PC-3 | IC50 |
28.59 μM
Compound: SQ-17
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Cytotoxicity against human PC-3 cells assessed as cell viability incubated for 96 hrs by MTT assay
Cytotoxicity against human PC-3 cells assessed as cell viability incubated for 96 hrs by MTT assay
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[PMID: 38153295] |
Chemical Information
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CAS No. 902563-50-2
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Molecular Weight 356.46
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Formula C21H28N2O3
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SMILES
O=C(NC1CCCCCC1)CCCOC2=CC(N(C)C3=CC=CC=C32)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BRD4 Inhibitor-29 Related Classifications
HY-157460 Related Classifications
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