BRD9 Degrader-3
BRD9 Degrader-3 is a selective BRD9 BRD9 molecular glue degrader degrader. BRD9 Degrader-3 consists of a BRD9-binding ligand, a linker, and a warhead that promotes proteasomal degradation of BRD9 via a non-canonical PROTAC mechanism independent of CRBN or VHL E3 ligases. BRD9 Degrader-3 can be used in cancer research, including studies of malignant rhabdoid tumors, specific sarcomas, and acute myeloid leukemia.
For research use only. We do not sell to patients.
- CAS No.: 3033018-77-5
- Formula: C39H46FN5O4
- Molecular Weight:667.81
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
BRD9 ≤ 1.25 nM (DC50) |
In Vitro
Chemical Information
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CAS No. 3033018-77-5
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Molecular Weight 667.81
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Formula C39H46FN5O4
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SMILES
FC1(/C=C(C#N)/C(N2C(C3=C(CC2)C(CN4CCN(CC4)CC5=C(OC)C=C(C(C(C)=C6C)=CN(C)C6=O)C=C5OC)=CC=C3)C)=O)CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BRD9 Degrader-3 Related Classifications
HY-163810 Related Classifications
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