TAT-327
TAT-327 is cell-penetrating peptide. TAT-327 selectively inserts into cancer cell membranes and shows potent antitumor activity. TAT-327 effectively inhibits cancer cells proliferation, induces apoptosis and disrupts EGFR signal pathway by inhibiting downstream signals (such as IL-2, TNF-α and IFN-γ) expression and the Eps8/EGFR interaction. TAT-327 significantly inhibits tumor growth in HT-29 xenograft mcie models.
For research use only. We do not sell to patients.
- Formula: C109H181N41O25S
- Molecular Weight:2497.93
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Biological Activity
Description
Chemical Information
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Molecular Weight 2497.93
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Formula C109H181N41O25S
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Sequence
Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Glu-Phe-Leu-Asp-Cys-Phe-Gln-Lys-Phe
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Sequence Shortening
RKKRRQRRREFLDCFQKF
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TAT-327 Related Classifications
HY-P10995 Related Classifications
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Keywords
- TAT-327
- TAT327
- TAT 327
- EGFR
- IFNAR
- Interleukin Related
- TNF Receptor
- Complement System
- Apoptosis
- Epidermal growth factor receptor
- ErbB-1
- HER1
- Interferon-α/β receptor
- Interferon-alpha/beta receptor
- IL
- Tumor Necrosis Factor Receptor
- TNFR
- Cell-penetrating peptide
- Antitumor
- A549 cells
- Colo320 cells
- HepG2 cells
- HT-29 cells
- HT-29 xenograft mcie models
- Inhibitor
- inhibitor
- inhibit