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Abrilumab

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Abrilumab is a fully human monoclonal antibody directed against α4β7. Abrilumab selectively binds the α4β7 integrin heterodimer. Abrilumab can be used for the research of inflammatory bowel disease (IBD).

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  • Pureté: 98.35%
  • CAS No.: 1342290-43-0
  • Masse moléculaire:143.8 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Abrilumab
  • Experimental Validation Results for Abrilumab
  • Experimental Validation Results for Abrilumab
  • Abrilumab Chemical Structure
    Abrilumab Chemical Structure
CAS No.: 1342290-43-0
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Abrilumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG2 kappa

  • 1/16

    Immobilized Human Integrin alpha 4 beta 7 (ITGA4&ITGB7) Heterodimer Protein, His Tag can bind Abrilumab. The EC50 for this effect is 4.74 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 Jurkat cells with Abrilumab (HY-P99184, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa Isotype Control (HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Abrilumab Chemical Structure
    1/16
  • Abrilumab
  • Immobilized Human Integrin alpha 4 beta 7 (ITGA4&ITGB7) Heterodimer Protein, His Tag can bind Abrilumab. The EC50 for this effect is 4.74 ng/mL.
  • Flow cytometric analysis of 1X106 Jurkat cells with Abrilumab (HY-P99184, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa Isotype Control (HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).