CDK9-IN-34
Based on 1 Customer Validation
CDK9-IN-34 (Compound 1b) is an inhibitor for CDK9 with an IC50 of 0.25 μM. CDK9-IN-34 exhibits cytotoxicity to cancer cell HCT116, MCF7 and K652 with IC50s of 1.43, 3.01 and 50.27 μM, respectively. CDK9-IN-34 exhibits antiviral activity against coronavirus 229E with an IC50 of 145.92 μM.
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- CAS No.: 252725-86-3
- Formule: C18H20N4
- Masse moléculaire:292.38
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
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CDK9 0.25 μM (IC50) |
Chemical Information
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CAS No. 252725-86-3
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Appearance Solid
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Masse moléculaire 292.38
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Formule C18H20N4
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SMILES
N12C=CN=CC1=NC(C3=CC=CC=C3)=C2NC4CCCCC4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 12.5 mg/mL (42.75 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (277 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4202 mL | 17.1010 mL | 34.2021 mL | 85.5052 mL |
| 5 mM | 0.6840 mL | 3.4202 mL | 6.8404 mL | 17.1010 mL | |
| 10 mM | 0.3420 mL | 1.7101 mL | 3.4202 mL | 8.5505 mL | |
| 15 mM | 0.2280 mL | 1.1401 mL | 2.2801 mL | 5.7003 mL | |
| 20 mM | 0.1710 mL | 0.8551 mL | 1.7101 mL | 4.2753 mL | |
| 25 mM | 0.1368 mL | 0.6840 mL | 1.3681 mL | 3.4202 mL | |
| 30 mM | 0.1140 mL | 0.5700 mL | 1.1401 mL | 2.8502 mL | |
| 40 mM | 0.0855 mL | 0.4275 mL | 0.8551 mL | 2.1376 mL |
CDK9-IN-34 Related Classifications
HY-164619 Related Classifications
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