Ceftibuten
Based on 2 publication(s) in Google Scholar
Ceftibuten (Sch39720), an antibiotic, is an orally active cephalosporin, possesses potent activity in vitro against a wide range of gram-negative and certain gram-positive pathogens.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 97519-39-6
- Formule: C15H14N4O6S2
- Masse moléculaire:410.42
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Ceftibuten
MoreVoir tous les produits spécifiques à Isoform Beta-lactamase
MoreVoir tous les produits spécifiques à Isoform Antibiotic
More
Activité biologique
|
β-lactam |
Ceftibuten (Sch39720) is highly active against Haemophilus influenza, Escherichia coli, Klebsiella sp., and Proteus sp. and moderately active against Serratia sp. and Streptococcus pyogenes. Ceftibuten is relatively inactive against enterococci and staphylococci and is only weakly active against Pseudomonas aeruginosa and obligate anaerobes. It is also stable in the presence of most β-lactamase-producing organisms except βBacteroides fragilis. Ceftibuten is very active against strains of the family Enterobacteriaceae (mean MIC for 90% of strains=0.25 μg/ml) but less active against Campylobacterjejuni (mean MIC for 90% of strains=16.0 μg/ml)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 97519-39-6
-
Masse moléculaire 410.42
-
Formule C15H14N4O6S2
-
SMILES
O=C(C(N12)=CCS[C@]2([H])[C@H](NC(/C(C3=CSC(N)=N3)=C\CC(O)=O)=O)C1=O)O
-
Synonyms
Sch 39720
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
-
Journal Impact Factor
-
Most Recent
-
SLAS Discov
2020 Sep;25(8):895-905. PMID: 32567455 -
Pureté et documentation
Références
[1]. Kearns GL, et al. Single-dose pharmacokinetics of ceftibuten (SCH 39720) in infants and children. Antimicrob Agents Chemother. 1991;35(10):2078-2084. [Content Brief]
[2]. Shawar R, et al. Comparative in vitro activity of ceftibuten (Sch 39720) against bacterial enteropathogens. Antimicrob Agents Chemother. 1989;33(5):781-784. [Content Brief]
[3]. Tamai I, et al. Functional expression of intestinal dipeptide/beta-lactam antibiotic transporter in Xenopus laevis oocytes. Biochem Pharmacol. 1994;48(5):881-888. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ceftibuten Related Classifications
HY-B0698 Related Classifications
Powered by Bioz