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Cat. No.: HY-P3528

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GPR

GPR is a three amino acid peptide. GPR can rescue cultured rat hippocampal neurons from Aβ-induced neuronal death by inhibiting caspase-3/p53 dependent apoptosis. GPR can be used for the research of Alzheimer's disease (AD).

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CAS No.: 47295-77-2
Formule: C₁₃H₂₄N₆O₄
Masse moléculaire:328.37

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Please store the product under the recommended conditions in the Certificate of Analysis.

GPR Chemical Structure

CAS No.: 47295-77-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
- Essai clinique
Chemical Information
Pureté et documentation
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Classifications
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Activité biologique

Description

Voir tous les produits spécifiques à Isoform Caspase :

In Vitro

GPR (1-100 μM; 24 h, 48 h) prevented Aβ-mediated increase in lactate dehydrogenase (LDH) release^[1].
GPR (50 μM; 24 h, 48 h) prevents Ah-mediated inhibition of neuronal MTT reduction^[1].
GPR (50 μM; 3 days) prevents Aβ-mediated increase in p53-positive cells^[1].
GPR (50 μM; 24 h) effectively prevented the Aβ-mediated activation of caspase-3^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis Analysis^[1]

Cell Line:

p53-positive cells
Concentration:

50 μM
Incubation Time:

3 days
Result:

Inhibited Ah-induced increase in numbers of p53-positive neurons.

Related Protocols :

Essai clinique

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 47295-77-2
Masse moléculaire 328.37
Formule C₁₃H₂₄N₆O₄
Sequence Shortening

GPR
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (243 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

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100 mg

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Activité biologique
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- In Vitro
- Essai clinique
Chemical Information
Pureté et documentation

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GPR

Voir tous les produits spécifiques à Isoform Caspase

Activité biologique

Description

In Vitro

Essai clinique

Chemical Information

Pureté et documentation

Calculators

Help & FAQs

GPR Related Classifications

HY-P3528 Related Classifications

Bioz

Keywords

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