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Cat. No.: HY-145356

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HbF inducer-1

HbF inducer-1 is an orally bioavailable fetal hemoglobin inducer.

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CAS No.: 2987004-95-3
Formule: C₁₈H₁₉N₃O₃
Masse moléculaire:325.36

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

HbF inducer-1 Chemical Structure

CAS No.: 2987004-95-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

HbF inducer-1 is an orally bioavailable fetal hemoglobin inducer.

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Cellular Effect

Cell Line	Type	Value	Description	References
CD34-positive (myeloid/lymphoid) cell	EC₅₀	2.8 μM Compound: 18	Induction of fetal hemoglobin in human bone marrow derived CD34+ cells incubated for 5 days by FITC staining based flow cytometry analysis Induction of fetal hemoglobin in human bone marrow derived CD34+ cells incubated for 5 days by FITC staining based flow cytometry analysis	[PMID: 32717372]

Chemical Information

CAS No. 2987004-95-3
Masse moléculaire 325.36
Formule C₁₈H₁₉N₃O₃
SMILES

CC(N1CC2(C1)CC(C2)NC(C3=CC(C4=CC=CC=C4)=NO3)=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Katayama K, et al. Design, synthesis, and optimization of a series of 2-azaspiro[3.3]heptane derivatives as orally bioavailable fetal hemoglobin inducers. Bioorg Med Chem Lett. 2020 Oct 1;30(19):127425. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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Activité biologique
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Chemical Information
Pureté et documentation
Références

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HbF inducer-1

Voir tous les produits spécifiques à Isoform Histone Methyltransferase