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Cat. No.: HY-119112A

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LY 379196

LY 379196 is a PKC-β inhibitor (IC₅₀: 50 nM and 30 nM for PKC βI and βII respectively). LY 379196 inhibits the VEGF, IGF-1 and bFGF-induced proliferation of bovine retinal microvascular endothelial cells (BREC). LY 379196 is an antiproliferatory agentfor proliferative retinopathy.

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Formule: C₃₀H₃₄N₄O₅S
Masse moléculaire:562.68

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

LY 379196 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Voir tous les produits spécifiques à Isoform PKC :

Chemical Information

Masse moléculaire 562.68
Formule C₃₀H₃₄N₄O₅S
SMILES

O=C1NC(C2=C1C(C3=CC=CC=C34)=CN4CCC[C@H](CN(C)C)CCN5C6=CC=CC=C6C2=C5)=O.O=S(O)(C)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Lin WW, et al. Distinct PKC isoforms mediate the activation of cPLA2 and adenylyl cyclase by phorbol ester in RAW264.7 macrophages. Br J Pharmacol. 1998 Dec;125(7):1601-9. [Content Brief]

[2]. G.E. Lang, et al. Effect of the PKC ß Inhibitor LY 379196 in Combination with Growth Factors on Proliferation of Bovine Retinal Vascular Endothelial Cells. ARVO Annual Meeting Abstract. May 2003

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Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Activité biologique
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Chemical Information
Pureté et documentation
Références

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LY 379196

Voir tous les produits spécifiques à Isoform PKC

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

LY 379196 Related Classifications

HY-119112A Related Classifications