SB-773812
SB-773812 is a moderate-affinity antagonist at dopamine receptor 2 (pKi=7.4) and a high-affinity antagonist at the dopamine receptor 3 (pKi=8.5) and at the serotonin 5-hydroxytryptamine receptors 2A (pKi=9.0), 2C (pKi=8.1), and 6 (pKi=8.1). SB-773812 is promising for research of central nervous system disorders.
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- CAS No.: 630407-66-8
- Formule: C25H26ClNO4S
- Masse moléculaire:472.00
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
IC50 & Target
|
D2 Receptor 7.4 (pKi) |
D3 Receptor 8.5 (pKi) |
5-HT2A Receptor 9.0 (pKi) |
5-HT2C Receptor 8.1 (pKi) |
5-HT6 Receptor 8.1 (pKi) |
Essai clinique
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 630407-66-8
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Masse moléculaire 472.00
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Formule C25H26ClNO4S
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SMILES
CN1CCC2=CC(OC)=C(S(=O)(C3=CC=C(OCC4=CC=C(Cl)C=C4)C=C3)=O)C=C2CC1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SB-773812 Related Classifications
HY-13051 Related Classifications
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