SET-12
SET-12 is an antiparasitic agent with high activity and selectivity against the Leishmania amazonensis. SET-12 exhibits excellent activity against the pre-flagellated form of the Leishmania amazonensis, with an IC₅₀ of 10.89 μM and a selectivity index (SI) of up to 12.1. SET-12 is also effective against the non-flagellated form within cells, with an IC₅₀ of 3.81 μM and a further increased selectivity index (SI) to 34.5. SET-12 causes signs of parasite cell apoptosis, including mitochondrial damage and accumulation of ROS.
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- CAS No.: 2241572-39-2
- Formule: C21H29NO4
- Masse moléculaire:359.46
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Chemical Information
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CAS No. 2241572-39-2
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Masse moléculaire 359.46
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Formule C21H29NO4
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SMILES
O=C1OC[C@H](C(C)C)N1C([C@H]([C@H](O)CCC2=CC=CC=C2)/C=C/CC)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SET-12 Related Classifications
HY-179710 Related Classifications
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