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Cat. No.: HY-14477

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UPF-1035

UPF-1035 is a selective PARP-2 inhibitor with an IC₅₀ value of 0.15 μM. UPF-1035 increases CA1 pyramidal cell loss in hippocampal and has neuroprotective activity.

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CAS No.: 370872-09-6
Formule: C₁₆H₁₁NO₃
Masse moléculaire:265.26

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

UPF-1035 Chemical Structure

CAS No.: 370872-09-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

UPF-1035 is a selective PARP-2 inhibitor with an IC₅₀ value of 0.15 μM. UPF-1035 increases CA1 pyramidal cell loss in hippocampal and has neuroprotective activity^[1].

IC₅₀ & Target

PARP-1

9 μM (IC₅₀)

PARP-2

0.15 μM (IC₅₀)

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Chemical Information

CAS No. 370872-09-6
Masse moléculaire 265.26
Formule C₁₆H₁₁NO₃
SMILES

O=C1C2=CC=CC(OC(C3=CC=CC=C3)=O)=C2C=CN1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. F Moroni , et al. Selective PARP-2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post-ischaemic brain damage. Br J Pharmacol. 2009 Jul;157(5):854-62. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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UPF-1035

High-Throughput Bioactive Compound Library

Voir tous les produits spécifiques à Isoform PARP

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

UPF-1035 Related Classifications

HY-14477 Related Classifications