CDK9-IN-27
CDK9-IN-27 (Compound 6a) is a CDK9 inhibitor (IC50s: 0.424 μM). CDK9-IN-27 induces apoptosis and cell cycle arrest at S stage. CDK9-IN-27 has cytotoxic action against HepG2, HCT-116 and MCF-7 cell lines, with IC50s of 10.31-40.34 μM. CDK9-IN-27 can be used for cancer research.
For research use only. We do not sell to patients.
- Formula: C23H18ClN5O3
- Molecular Weight:447.87
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
0.424 μM (CDK9)[1]
Chemical Information
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Molecular Weight 447.87
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Formula C23H18ClN5O3
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SMILES
ClC(C=C1)=CC=C1C(C(C(OCC)=O)=C(N)N2CC3=NC4=CC=CC=C4N3)=C(C#N)C2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)