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Art. -Nr.: HY-118299

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JYL 1511

JYL 1511 is a partial agonist of vanilloid receptor VR1.

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CAS. Nr.: 623166-14-3
Formel: C₂₁H₂₉N₃O₃S₂
Molecular Weight:435.60

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

JYL 1511 Chemical Structure

CAS. Nr.: 623166-14-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

JYL 1511 is a partial agonist of vanilloid receptor VR1^[1].

Alle TRP Channel Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	EC₅₀	32.4 nM Compound: 3	Agonist activity at rat TRPV1 expressed in CHO cells by 45Ca2+ uptake assay Agonist activity at rat TRPV1 expressed in CHO cells by 45Ca2+ uptake assay	[PMID: 18406014]

In Vitro

JYL 1511 inhibits ^[3H]Resiniferatoxin binding to rat VR1 with a K_i of 50.4 nM^[1].
JYL 1511 inhibits Capsaicin induction of ⁴⁵Ca²⁺ uptake in CHO cells overexpressing rat VR1 (IC₅₀: 3.4 nM)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 623166-14-3
Molecular Weight 435.60
Formel C₂₁H₂₉N₃O₃S₂
SMILES

CS(=O)(NC1=CC=C(C=C1OC)CNC(NCC2=CC=C(C=C2)C(C)(C)C)=S)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Wang Y, et al. High-affinity partial agonists of the vanilloid receptor. Mol Pharmacol. 2003 Aug;64(2):325-33. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

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100 mg

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise

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JYL 1511

Alle TRP Channel Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

JYL 1511 Related Classifications

HY-118299 Related Classifications