PF-06465603
PF-06465603 is a highly potent and selective ATP-competitive kinase inhibitor and a class 1 PI3K and mTOR inhibitor. PF-06465603 is a metabolite of PF-04691502 with a terminal carboxylic acid structure.
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- CAS. Nr.: 1431626-44-6
- Formel: C22H25N5O5
- Molecular Weight:439.46
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BT-20 | IC50 |
2070 nM
Compound: 10, PF-06465603
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Inhibition of AKT phosphorylation at Ser 473 in human BT20 cells
Inhibition of AKT phosphorylation at Ser 473 in human BT20 cells
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[PMID: 23506825] |
Chemical Information
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CAS. Nr. 1431626-44-6
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Molecular Weight 439.46
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Formel C22H25N5O5
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SMILES
O=C(O)CO[C@@H]1CC[C@@H](N(C2=NC(N)=NC(C)=C2C=C3C4=CC=C(OC)N=C4)C3=O)CC1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
PF-06465603 Related Classifications
HY-117923 Related Classifications
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